INAVA (innate immunity activator)

2018-11-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
C1orf106

Other Information

Locus ID:

NCBI: 55765
MIM: 618051
HGNC: 25599
Ensembl: ENSG00000163362

Variants:

dbSNP: 55765
ClinVar: 55765
TCGA: ENSG00000163362
COSMIC: INAVA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163362ENST00000367342Q3KP66
ENSG00000163362ENST00000413687Q3KP66
ENSG00000163362ENST00000451872C9JAT8
ENSG00000163362ENST00000532631E9PK29

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
294202622018C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.23
279806952016Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.4
284369392017An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes.2
303554482018INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling.2
310226982018Inflammatory Bowel Disease Susceptibility Gene C1ORF106 Regulates Intestinal Epithelial Permeability.1

Citation

Dessen P

INAVA (innate immunity activator)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80641/inava