INCA1 (inhibitor of CDK, cyclin A1 interacting protein 1)

2012-05-01  

Identity

HGNC
INCA1
LOCATION
17p13.2
LOCUSID
388324
ALIAS
HSD45
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 388324
MIM: 617374
HGNC: 32224
Ensembl: ENSG00000196388

Variants:

dbSNP: 388324
ClinVar: 388324
TCGA: ENSG00000196388
COSMIC: INCA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196388ENST00000355025Q0VD86
ENSG00000196388ENST00000574617Q0VD86
ENSG00000196388ENST00000575780Q0VD86
ENSG00000196388ENST00000576820Q0VD86

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
217507152011The inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effects.15
215401872011Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.0

Citation

Dessen P

INCA1 (inhibitor of CDK, cyclin A1 interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-05-01

Online version: http://atlasgeneticsoncology.org/gene/52715/inca1