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INCENP (inner centromere protein)

Identity

Alias (NCBI)-
HGNC (Hugo) INCENP
HGNC Alias symbFLJ31633
HGNC Previous nameinner centromere protein antigens (135kD, 155kD)
 inner centromere protein antigens 135/155kDa
LocusID (NCBI) 3619
Atlas_Id 43317
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62124011 and ends at 62153166 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)INCENP   6058
Cards
Entrez_Gene (NCBI)INCENP    inner centromere protein
Aliases
GeneCards (Weizmann)INCENP
Ensembl hg19 (Hinxton)ENSG00000149503 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149503 [Gene_View]  ENSG00000149503 [Sequence]  chr11:62124011-62153166 [Contig_View]  INCENP [Vega]
ICGC DataPortalENSG00000149503
TCGA cBioPortalINCENP
AceView (NCBI)INCENP
Genatlas (Paris)INCENP
SOURCE (Princeton)INCENP
Genetics Home Reference (NIH)INCENP
Genomic and cartography
GoldenPath hg38 (UCSC)INCENP  -     chr11:62124011-62153166 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INCENP  -     11q12.3   [Description]    (hg19-Feb_2009)
GoldenPathINCENP - 11q12.3 [CytoView hg19]  INCENP - 11q12.3 [CytoView hg38]
ImmunoBaseENSG00000149503
genome Data Viewer NCBIINCENP [Mapview hg19]  
OMIM604411   
Gene and transcription
Genbank (Entrez)AF282265 AK056195 AK307633 AK310714 AW839685
RefSeq transcript (Entrez)NM_001040694 NM_020238
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INCENP
Alternative Splicing GalleryENSG00000149503
Gene ExpressionINCENP [ NCBI-GEO ]   INCENP [ EBI - ARRAY_EXPRESS ]   INCENP [ SEEK ]   INCENP [ MEM ]
Gene Expression Viewer (FireBrowse)INCENP [ Firebrowse - Broad ]
GenevisibleExpression of INCENP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3619
GTEX Portal (Tissue expression)INCENP
Human Protein AtlasENSG00000149503-INCENP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQS7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQS7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQS7
Splice isoforms : SwissVarQ9NQS7
PhosPhoSitePlusQ9NQS7
Domains : Interpro (EBI)INCENP    INCENP_N    Inner_centromere_prot_ARK-bd   
Domain families : Pfam (Sanger)INCENP_ARK-bind (PF03941)    INCENP_N (PF12178)   
Domain families : Pfam (NCBI)pfam03941    pfam12178   
Conserved Domain (NCBI)INCENP
Blocks (Seattle)INCENP
PDB (RSDB)2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
PDB Europe2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
PDB (PDBSum)2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
PDB (IMB)2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
Structural Biology KnowledgeBase2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
SCOP (Structural Classification of Proteins)2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
CATH (Classification of proteins structures)2QFA    4AF3    5IEH    5IEK    6GR8    6GR9   
SuperfamilyQ9NQS7
Human Protein Atlas [tissue]ENSG00000149503-INCENP [tissue]
Peptide AtlasQ9NQS7
HPRD05103
IPIIPI00876972   IPI00759472   IPI00983394   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQS7
IntAct (EBI)Q9NQS7
BioGRIDINCENP
STRING (EMBL)INCENP
ZODIACINCENP
Ontologies - Pathways
QuickGOQ9NQS7
Ontology : AmiGOmitotic sister chromatid segregation  mitotic cytokinesis  mitotic cytokinesis  chromosome, centromeric region  kinetochore  kinetochore  condensed chromosome kinetochore  condensed chromosome  lateral element  central element  protein binding  nucleus  nucleoplasm  nucleoplasm  pericentric heterochromatin  spindle  cytosol  cytosol  microtubule  chromosome segregation  meiotic chromosome condensation  chromocenter  histone phosphorylation  nuclear body  midbody  midbody  chromosome passenger complex  protein-containing complex  protein serine/threonine kinase activator activity  meiotic spindle midzone assembly  metaphase plate congression  positive regulation of protein serine/threonine kinase activity  regulation of mitotic cytokinesis  meiotic spindle midzone  
Ontology : EGO-EBImitotic sister chromatid segregation  mitotic cytokinesis  mitotic cytokinesis  chromosome, centromeric region  kinetochore  kinetochore  condensed chromosome kinetochore  condensed chromosome  lateral element  central element  protein binding  nucleus  nucleoplasm  nucleoplasm  pericentric heterochromatin  spindle  cytosol  cytosol  microtubule  chromosome segregation  meiotic chromosome condensation  chromocenter  histone phosphorylation  nuclear body  midbody  midbody  chromosome passenger complex  protein-containing complex  protein serine/threonine kinase activator activity  meiotic spindle midzone assembly  metaphase plate congression  positive regulation of protein serine/threonine kinase activity  regulation of mitotic cytokinesis  meiotic spindle midzone  
NDEx NetworkINCENP
Atlas of Cancer Signalling NetworkINCENP
Wikipedia pathwaysINCENP
Orthology - Evolution
OrthoDB3619
GeneTree (enSembl)ENSG00000149503
Phylogenetic Trees/Animal Genes : TreeFamINCENP
HOGENOMQ9NQS7
Homologs : HomoloGeneINCENP
Homology/Alignments : Family Browser (UCSC)INCENP
Gene fusions - Rearrangements
Fusion : QuiverINCENP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINCENP [hg38]
dbVarINCENP
ClinVarINCENP
MonarchINCENP
1000_GenomesINCENP 
Exome Variant ServerINCENP
GNOMAD BrowserENSG00000149503
Varsome BrowserINCENP
Genomic Variants (DGV)INCENP [DGVbeta]
DECIPHERINCENP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINCENP 
Mutations
ICGC Data PortalINCENP 
TCGA Data PortalINCENP 
Broad Tumor PortalINCENP
OASIS PortalINCENP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINCENP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DINCENP
Mutations and Diseases : HGMDINCENP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INCENP
DgiDB (Drug Gene Interaction Database)INCENP
DoCM (Curated mutations)INCENP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INCENP (select a term)
intoGenINCENP
Cancer3DINCENP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604411   
Orphanet
DisGeNETINCENP
MedgenINCENP
Genetic Testing Registry INCENP
NextProtQ9NQS7 [Medical]
GENETestsINCENP
Target ValidationINCENP
Huge Navigator INCENP [HugePedia]
ClinGenINCENP
Clinical trials, drugs, therapy
MyCancerGenomeINCENP
Protein Interactions : CTD
Pharm GKB GenePA29868
PharosQ9NQS7
Clinical trialINCENP
Miscellaneous
canSAR (ICR)INCENP (select the gene name)
HarmonizomeINCENP
DataMed IndexINCENP
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXINCENP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:20:19 CET 2021

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