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INF2 (inverted formin, FH2 and WH2 domain containing)

Identity

Alias_namesC14orf151
C14orf173
chromosome 14 open reading frame 151
chromosome 14 open reading frame 173
Alias_symbol (synonym)MGC13251
Other aliasCMTDIE
FSGS5
pp9484
HGNC (Hugo) INF2
LocusID (NCBI) 64423
Atlas_Id 64617
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 104689606 and ends at 104719610 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
INF2 (14q32.33) / INF2 (14q32.33)INF2 (14q32.33) / TGIF2-C20orf24 (20q11.23)INF2 (14q32.33) / VPS13C (15q22.2)
S100A6 (1q21.3) / INF2 (14q32.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INF2   23791
Cards
Entrez_Gene (NCBI)INF2  64423  inverted formin, FH2 and WH2 domain containing
AliasesC14orf151; C14orf173; CMTDIE; FSGS5; 
pp9484
GeneCards (Weizmann)INF2
Ensembl hg19 (Hinxton)ENSG00000203485 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203485 [Gene_View]  chr14:104689606-104719610 [Contig_View]  INF2 [Vega]
ICGC DataPortalENSG00000203485
TCGA cBioPortalINF2
AceView (NCBI)INF2
Genatlas (Paris)INF2
WikiGenes64423
SOURCE (Princeton)INF2
Genetics Home Reference (NIH)INF2
Genomic and cartography
GoldenPath hg38 (UCSC)INF2  -     chr14:104689606-104719610 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INF2  -     14q32.33   [Description]    (hg19-Feb_2009)
EnsemblINF2 - 14q32.33 [CytoView hg19]  INF2 - 14q32.33 [CytoView hg38]
Mapping of homologs : NCBIINF2 [Mapview hg19]  INF2 [Mapview hg38]
OMIM610982   613237   614455   
Gene and transcription
Genbank (Entrez)AF318379 AK025709 AK027105 AK225325 AK290083
RefSeq transcript (Entrez)NM_001031714 NM_022489 NM_032714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INF2
Cluster EST : UnigeneHs.24956 [ NCBI ]
CGAP (NCI)Hs.24956
Alternative Splicing GalleryENSG00000203485
Gene ExpressionINF2 [ NCBI-GEO ]   INF2 [ EBI - ARRAY_EXPRESS ]   INF2 [ SEEK ]   INF2 [ MEM ]
Gene Expression Viewer (FireBrowse)INF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64423
GTEX Portal (Tissue expression)INF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ27J81   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ27J81  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ27J81
Splice isoforms : SwissVarQ27J81
PhosPhoSitePlusQ27J81
Domaine pattern : Prosite (Expaxy)FH2 (PS51444)    GBD_FH3 (PS51232)    WH2 (PS51082)   
Domains : Interpro (EBI)ARM-type_fold    FH2_Formin    FH3_dom    GBD/FH3_dom    GTPase-bd    Inf2    WH2_dom   
Domain families : Pfam (Sanger)Drf_FH3 (PF06367)    Drf_GBD (PF06371)    FH2 (PF02181)    WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam06367    pfam06371    pfam02181    pfam02205   
Domain families : Smart (EMBL)Drf_FH3 (SM01139)  Drf_GBD (SM01140)  FH2 (SM00498)  
Conserved Domain (NCBI)INF2
DMDM Disease mutations64423
Blocks (Seattle)INF2
SuperfamilyQ27J81
Human Protein AtlasENSG00000203485
Peptide AtlasQ27J81
HPRD08648
IPIIPI00895800   IPI00876962   IPI00937711   IPI00759825   IPI00383273   IPI00024577   IPI01024956   IPI01026448   
Protein Interaction databases
DIP (DOE-UCLA)Q27J81
IntAct (EBI)Q27J81
FunCoupENSG00000203485
BioGRIDINF2
STRING (EMBL)INF2
ZODIACINF2
Ontologies - Pathways
QuickGOQ27J81
Ontology : AmiGOactin binding  Rho GTPase binding  actin cytoskeleton organization  perinuclear region of cytoplasm  regulation of mitochondrial fission  
Ontology : EGO-EBIactin binding  Rho GTPase binding  actin cytoskeleton organization  perinuclear region of cytoplasm  regulation of mitochondrial fission  
NDEx NetworkINF2
Atlas of Cancer Signalling NetworkINF2
Wikipedia pathwaysINF2
Orthology - Evolution
OrthoDB64423
GeneTree (enSembl)ENSG00000203485
Phylogenetic Trees/Animal Genes : TreeFamINF2
HOVERGENQ27J81
HOGENOMQ27J81
Homologs : HomoloGeneINF2
Homology/Alignments : Family Browser (UCSC)INF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INF2
dbVarINF2
ClinVarINF2
1000_GenomesINF2 
Exome Variant ServerINF2
ExAC (Exome Aggregation Consortium)INF2 (select the gene name)
Genetic variants : HAPMAP64423
Genomic Variants (DGV)INF2 [DGVbeta]
DECIPHERINF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINF2 
Mutations
ICGC Data PortalINF2 
TCGA Data PortalINF2 
Broad Tumor PortalINF2
OASIS PortalINF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INF2
DgiDB (Drug Gene Interaction Database)INF2
DoCM (Curated mutations)INF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INF2 (select a term)
intoGenINF2
Cancer3DINF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610982    613237    614455   
Orphanet12169    12191   
MedgenINF2
Genetic Testing Registry INF2
NextProtQ27J81 [Medical]
TSGene64423
GENETestsINF2
Target ValidationINF2
Huge Navigator INF2 [HugePedia]
snp3D : Map Gene to Disease64423
BioCentury BCIQINF2
ClinGenINF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64423
Chemical/Pharm GKB GenePA162392025
Clinical trialINF2
Miscellaneous
canSAR (ICR)INF2 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINF2
EVEXINF2
GoPubMedINF2
iHOPINF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:53:29 CEST 2017

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