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ING5 (inhibitor of growth family member 5)

Identity

Alias_symbol (synonym)FLJ23842
p28ING5
Other alias
HGNC (Hugo) ING5
LocusID (NCBI) 84289
Atlas_Id 40979
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 241687012 and ends at 241721807 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(2;8)(p23;p11) KAT6A/ASXL2
t(9;22)(p13;q13) PAX5/BRD1


External links

Nomenclature
HGNC (Hugo)ING5   19421
Cards
Entrez_Gene (NCBI)ING5  84289  inhibitor of growth family member 5
Aliasesp28ING5
GeneCards (Weizmann)ING5
Ensembl hg19 (Hinxton)ENSG00000168395 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168395 [Gene_View]  chr2:241687012-241721807 [Contig_View]  ING5 [Vega]
ICGC DataPortalENSG00000168395
TCGA cBioPortalING5
AceView (NCBI)ING5
Genatlas (Paris)ING5
WikiGenes84289
SOURCE (Princeton)ING5
Genetics Home Reference (NIH)ING5
Genomic and cartography
GoldenPath hg38 (UCSC)ING5  -     chr2:241687012-241721807 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ING5  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblING5 - 2q37.3 [CytoView hg19]  ING5 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBIING5 [Mapview hg19]  ING5 [Mapview hg38]
OMIM608525   
Gene and transcription
Genbank (Entrez)AF189286 AI701412 AK074422 AK128322 AK289958
RefSeq transcript (Entrez)NM_001330161 NM_001330162 NM_032329
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ING5
Cluster EST : UnigeneHs.529172 [ NCBI ]
CGAP (NCI)Hs.529172
Alternative Splicing GalleryENSG00000168395
Gene ExpressionING5 [ NCBI-GEO ]   ING5 [ EBI - ARRAY_EXPRESS ]   ING5 [ SEEK ]   ING5 [ MEM ]
Gene Expression Viewer (FireBrowse)ING5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84289
GTEX Portal (Tissue expression)ING5
Human Protein AtlasENSG00000168395-ING5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WYH8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WYH8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WYH8
Splice isoforms : SwissVarQ8WYH8
PhosPhoSitePlusQ8WYH8
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)   
Domains : Interpro (EBI)ING5    ING_fam    ING_N_histone_binding    Zinc_finger_PHD-type_CS    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)ING (PF12998)   
Domain families : Pfam (NCBI)pfam12998   
Domain families : Smart (EMBL)ING (SM01408)  PHD (SM00249)  
Conserved Domain (NCBI)ING5
DMDM Disease mutations84289
Blocks (Seattle)ING5
PDB (SRS)3C6W   
PDB (PDBSum)3C6W   
PDB (IMB)3C6W   
PDB (RSDB)3C6W   
Structural Biology KnowledgeBase3C6W   
SCOP (Structural Classification of Proteins)3C6W   
CATH (Classification of proteins structures)3C6W   
SuperfamilyQ8WYH8
Human Protein Atlas [tissue]ENSG00000168395-ING5 [tissue]
Peptide AtlasQ8WYH8
HPRD16348
IPIIPI00782935   IPI00513864   IPI00894159   
Protein Interaction databases
DIP (DOE-UCLA)Q8WYH8
IntAct (EBI)Q8WYH8
FunCoupENSG00000168395
BioGRIDING5
STRING (EMBL)ING5
ZODIACING5
Ontologies - Pathways
QuickGOQ8WYH8
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  DNA replication  transcription, DNA-templated  protein acetylation  zinc ion binding  negative regulation of cell proliferation  negative regulation of cell proliferation  methylated histone binding  positive regulation of apoptotic process  histone H3 acetylation  positive regulation of transcription, DNA-templated  negative regulation of growth  MOZ/MORF histone acetyltransferase complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  DNA replication  transcription, DNA-templated  protein acetylation  zinc ion binding  negative regulation of cell proliferation  negative regulation of cell proliferation  methylated histone binding  positive regulation of apoptotic process  histone H3 acetylation  positive regulation of transcription, DNA-templated  negative regulation of growth  MOZ/MORF histone acetyltransferase complex  regulation of signal transduction by p53 class mediator  
NDEx NetworkING5
Atlas of Cancer Signalling NetworkING5
Wikipedia pathwaysING5
Orthology - Evolution
OrthoDB84289
GeneTree (enSembl)ENSG00000168395
Phylogenetic Trees/Animal Genes : TreeFamING5
HOVERGENQ8WYH8
HOGENOMQ8WYH8
Homologs : HomoloGeneING5
Homology/Alignments : Family Browser (UCSC)ING5
Gene fusions - Rearrangements
Tumor Fusion PortalING5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerING5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ING5
dbVarING5
ClinVarING5
1000_GenomesING5 
Exome Variant ServerING5
ExAC (Exome Aggregation Consortium)ENSG00000168395
GNOMAD BrowserENSG00000168395
Genetic variants : HAPMAP84289
Genomic Variants (DGV)ING5 [DGVbeta]
DECIPHERING5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisING5 
Mutations
ICGC Data PortalING5 
TCGA Data PortalING5 
Broad Tumor PortalING5
OASIS PortalING5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICING5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDING5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ING5
DgiDB (Drug Gene Interaction Database)ING5
DoCM (Curated mutations)ING5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ING5 (select a term)
intoGenING5
Cancer3DING5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608525   
Orphanet
DisGeNETING5
MedgenING5
Genetic Testing Registry ING5
NextProtQ8WYH8 [Medical]
TSGene84289
GENETestsING5
Target ValidationING5
Huge Navigator ING5 [HugePedia]
snp3D : Map Gene to Disease84289
BioCentury BCIQING5
ClinGenING5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84289
Chemical/Pharm GKB GenePA134935441
Clinical trialING5
Miscellaneous
canSAR (ICR)ING5 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineING5
EVEXING5
GoPubMedING5
iHOPING5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:51 CET 2017

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