Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

INHBB (inhibin beta B)

Identity

Alias_namesinhibin, beta B (activin AB beta polypeptide)
inhibin, beta B
Other alias-
HGNC (Hugo) INHBB
LocusID (NCBI) 3625
Atlas_Id 40981
Location 2q14.2  [Link to chromosome band 2q14]
Location_base_pair Starts at 121103719 and ends at 121109383 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INHBB   6067
Cards
Entrez_Gene (NCBI)INHBB  3625  inhibin beta B
Aliases
GeneCards (Weizmann)INHBB
Ensembl hg19 (Hinxton)ENSG00000163083 [Gene_View]  chr2:121103719-121109383 [Contig_View]  INHBB [Vega]
Ensembl hg38 (Hinxton)ENSG00000163083 [Gene_View]  chr2:121103719-121109383 [Contig_View]  INHBB [Vega]
ICGC DataPortalENSG00000163083
TCGA cBioPortalINHBB
AceView (NCBI)INHBB
Genatlas (Paris)INHBB
WikiGenes3625
SOURCE (Princeton)INHBB
Genetics Home Reference (NIH)INHBB
Genomic and cartography
GoldenPath hg19 (UCSC)INHBB  -     chr2:121103719-121109383 +  2q14.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)INHBB  -     2q14.2   [Description]    (hg38-Dec_2013)
EnsemblINHBB - 2q14.2 [CytoView hg19]  INHBB - 2q14.2 [CytoView hg38]
Mapping of homologs : NCBIINHBB [Mapview hg19]  INHBB [Mapview hg38]
OMIM147390   
Gene and transcription
Genbank (Entrez)AA416873 AI659282 BC030029 BC127815 BF938974
RefSeq transcript (Entrez)NM_002193
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929304
Consensus coding sequences : CCDS (NCBI)INHBB
Cluster EST : UnigeneHs.1735 [ NCBI ]
CGAP (NCI)Hs.1735
Alternative Splicing GalleryENSG00000163083
Gene ExpressionINHBB [ NCBI-GEO ]   INHBB [ EBI - ARRAY_EXPRESS ]   INHBB [ SEEK ]   INHBB [ MEM ]
Gene Expression Viewer (FireBrowse)INHBB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3625
GTEX Portal (Tissue expression)INHBB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09529   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09529  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09529
Splice isoforms : SwissVarP09529
PhosPhoSitePlusP09529
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Inhibin_betaB    TGF-b_C    TGF-b_N    TGF-beta-rel    TGFb_CS   
Domain families : Pfam (Sanger)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (NCBI)pfam00019    pfam00688   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)INHBB
DMDM Disease mutations3625
Blocks (Seattle)INHBB
SuperfamilyP09529
Human Protein AtlasENSG00000163083
Peptide AtlasP09529
HPRD00934
IPIIPI00297026   
Protein Interaction databases
DIP (DOE-UCLA)P09529
IntAct (EBI)P09529
FunCoupENSG00000163083
BioGRIDINHBB
STRING (EMBL)INHBB
ZODIACINHBB
Ontologies - Pathways
QuickGOP09529
Ontology : AmiGOovarian follicle development  cytokine activity  transforming growth factor beta receptor binding  hormone activity  protein binding  extracellular region  extracellular space  defense response  growth factor activity  cellular response to starvation  response to mechanical stimulus  positive regulation of pathway-restricted SMAD protein phosphorylation  cell differentiation  cellular response to insulin stimulus  activin receptor signaling pathway  growth  protein homodimerization activity  regulation of apoptotic process  regulation of MAPK cascade  cellular response to leptin stimulus  fat cell differentiation  negative regulation of insulin secretion  host cell surface receptor binding  positive regulation of follicle-stimulating hormone secretion  negative regulation of follicle-stimulating hormone secretion  negative regulation of hepatocyte growth factor biosynthetic process  cell development  perinuclear region of cytoplasm  oocyte development  positive regulation of ovulation  SMAD protein signal transduction  cell periphery  positive regulation of apoptotic signaling pathway  
Ontology : EGO-EBIovarian follicle development  cytokine activity  transforming growth factor beta receptor binding  hormone activity  protein binding  extracellular region  extracellular space  defense response  growth factor activity  cellular response to starvation  response to mechanical stimulus  positive regulation of pathway-restricted SMAD protein phosphorylation  cell differentiation  cellular response to insulin stimulus  activin receptor signaling pathway  growth  protein homodimerization activity  regulation of apoptotic process  regulation of MAPK cascade  cellular response to leptin stimulus  fat cell differentiation  negative regulation of insulin secretion  host cell surface receptor binding  positive regulation of follicle-stimulating hormone secretion  negative regulation of follicle-stimulating hormone secretion  negative regulation of hepatocyte growth factor biosynthetic process  cell development  perinuclear region of cytoplasm  oocyte development  positive regulation of ovulation  SMAD protein signal transduction  cell periphery  positive regulation of apoptotic signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    TGF-beta signaling pathway   
NDEx NetworkINHBB
Atlas of Cancer Signalling NetworkINHBB
Wikipedia pathwaysINHBB
Orthology - Evolution
OrthoDB3625
GeneTree (enSembl)ENSG00000163083
Phylogenetic Trees/Animal Genes : TreeFamINHBB
HOVERGENP09529
HOGENOMP09529
Homologs : HomoloGeneINHBB
Homology/Alignments : Family Browser (UCSC)INHBB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINHBB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INHBB
dbVarINHBB
ClinVarINHBB
1000_GenomesINHBB 
Exome Variant ServerINHBB
ExAC (Exome Aggregation Consortium)INHBB (select the gene name)
Genetic variants : HAPMAP3625
Genomic Variants (DGV)INHBB [DGVbeta]
DECIPHER (Syndromes)2:121103719-121109383  ENSG00000163083
CONAN: Copy Number AnalysisINHBB 
Mutations
ICGC Data PortalINHBB 
TCGA Data PortalINHBB 
Broad Tumor PortalINHBB
OASIS PortalINHBB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINHBB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINHBB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INHBB
DgiDB (Drug Gene Interaction Database)INHBB
DoCM (Curated mutations)INHBB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INHBB (select a term)
intoGenINHBB
Cancer3DINHBB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147390   
Orphanet
MedgenINHBB
Genetic Testing Registry INHBB
NextProtP09529 [Medical]
TSGene3625
GENETestsINHBB
Huge Navigator INHBB [HugePedia]
snp3D : Map Gene to Disease3625
BioCentury BCIQINHBB
ClinGenINHBB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3625
Chemical/Pharm GKB GenePA29878
Clinical trialINHBB
Miscellaneous
canSAR (ICR)INHBB (select the gene name)
Probes
Litterature
PubMed102 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINHBB
EVEXINHBB
GoPubMedINHBB
iHOPINHBB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:05:15 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.