INHBC (inhibin subunit beta C)

2003-12-01  

Identity

HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
IHBC

Other Information

Locus ID:

NCBI: 3626
MIM: 601233
HGNC: 6068
Ensembl: ENSG00000175189

Variants:

dbSNP: 3626
ClinVar: 3626
TCGA: ENSG00000175189
COSMIC: INHBC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175189ENST00000309668P55103

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
TGF-beta signaling pathwayKEGGko04350
Cytokine-cytokine receptor interactionKEGGhsa04060
TGF-beta signaling pathwayKEGGhsa04350
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Activin signalingKEGGhsa_M00681
Activin signalingKEGGM00681
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Peptide hormone biosynthesisREACTOMER-HSA-209952
Glycoprotein hormonesREACTOMER-HSA-209822

References

Pubmed IDYearTitleCitations
281166722017Over-Expression of Activin-β(C) Is Associated with Murine and Human Prostate Disease.3
281166722017Over-Expression of Activin-β(C) Is Associated with Murine and Human Prostate Disease.3
245992872014Serum inhibin A and inhibin B levels in epithelial ovarian cancer patients.13
250624512014Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.18
245992872014Serum inhibin A and inhibin B levels in epithelial ovarian cancer patients.13
250624512014Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.18
231802942013Activin-β(c) reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice.9
235800132013The inhibin-βC subunit is down-regulated, while inhibin-βE is up-regulated by interferon-β1a in Ishikawa carcinoma cell line.4
231802942013Activin-β(c) reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice.9
235800132013The inhibin-βC subunit is down-regulated, while inhibin-βE is up-regulated by interferon-β1a in Ishikawa carcinoma cell line.4
232847512012SNPs in the TGF-β signaling pathway are associated with increased risk of brain metastasis in patients with non-small-cell lung cancer.15
232847512012SNPs in the TGF-β signaling pathway are associated with increased risk of brain metastasis in patients with non-small-cell lung cancer.15
206836032011Inhibin/activin-betaC subunit does not represent a prognostic parameter in human endometrial cancer.2
210634442011Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene.19
211178332011Inhibin-betaC subunit expression in normal and pathological human placental tissues.2

Citation

Dessen P

INHBC (inhibin subunit beta C)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40982/inhbc