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INHBC (inhibin subunit beta C)

Identity

Alias_namesinhibin
Other aliasIHBC
HGNC (Hugo) INHBC
LocusID (NCBI) 3626
Atlas_Id 40982
Location 12q13.3  [Link to chromosome band 12q13]
Location_base_pair Starts at 57434685 and ends at 57452062 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INHBC   6068
Cards
Entrez_Gene (NCBI)INHBC  3626  inhibin subunit beta C
AliasesIHBC
GeneCards (Weizmann)INHBC
Ensembl hg19 (Hinxton)ENSG00000175189 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175189 [Gene_View]  ENSG00000175189 [Sequence]  chr12:57434685-57452062 [Contig_View]  INHBC [Vega]
ICGC DataPortalENSG00000175189
TCGA cBioPortalINHBC
AceView (NCBI)INHBC
Genatlas (Paris)INHBC
WikiGenes3626
SOURCE (Princeton)INHBC
Genetics Home Reference (NIH)INHBC
Genomic and cartography
GoldenPath hg38 (UCSC)INHBC  -     chr12:57434685-57452062 +  12q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INHBC  -     12q13.3   [Description]    (hg19-Feb_2009)
EnsemblINHBC - 12q13.3 [CytoView hg19]  INHBC - 12q13.3 [CytoView hg38]
Mapping of homologs : NCBIINHBC [Mapview hg19]  INHBC [Mapview hg38]
OMIM601233   
Gene and transcription
Genbank (Entrez)AK314849 BC020693 BC130324 BC130326 BP237373
RefSeq transcript (Entrez)NM_005538
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INHBC
Cluster EST : UnigeneHs.632722 [ NCBI ]
CGAP (NCI)Hs.632722
Alternative Splicing GalleryENSG00000175189
Gene ExpressionINHBC [ NCBI-GEO ]   INHBC [ EBI - ARRAY_EXPRESS ]   INHBC [ SEEK ]   INHBC [ MEM ]
Gene Expression Viewer (FireBrowse)INHBC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3626
GTEX Portal (Tissue expression)INHBC
Human Protein AtlasENSG00000175189-INHBC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55103   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55103  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55103
Splice isoforms : SwissVarP55103
PhosPhoSitePlusP55103
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Inhibin_betaC    TGF-b_C    TGF-beta-rel    TGFb_CS   
Domain families : Pfam (Sanger)TGF_beta (PF00019)   
Domain families : Pfam (NCBI)pfam00019   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)INHBC
DMDM Disease mutations3626
Blocks (Seattle)INHBC
SuperfamilyP55103
Human Protein Atlas [tissue]ENSG00000175189-INHBC [tissue]
Peptide AtlasP55103
HPRD03136
IPIIPI00023314   IPI01022392   
Protein Interaction databases
DIP (DOE-UCLA)P55103
IntAct (EBI)P55103
FunCoupENSG00000175189
BioGRIDINHBC
STRING (EMBL)INHBC
ZODIACINHBC
Ontologies - Pathways
QuickGOP55103
Ontology : AmiGOcytokine activity  transforming growth factor beta receptor binding  hormone activity  extracellular region  extracellular space  growth factor activity  regulation of signaling receptor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  regulation of apoptotic process  regulation of MAPK cascade  cell development  SMAD protein signal transduction  
Ontology : EGO-EBIcytokine activity  transforming growth factor beta receptor binding  hormone activity  extracellular region  extracellular space  growth factor activity  regulation of signaling receptor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  regulation of apoptotic process  regulation of MAPK cascade  cell development  SMAD protein signal transduction  
Pathways : KEGGCytokine-cytokine receptor interaction    TGF-beta signaling pathway   
NDEx NetworkINHBC
Atlas of Cancer Signalling NetworkINHBC
Wikipedia pathwaysINHBC
Orthology - Evolution
OrthoDB3626
GeneTree (enSembl)ENSG00000175189
Phylogenetic Trees/Animal Genes : TreeFamINHBC
HOVERGENP55103
HOGENOMP55103
Homologs : HomoloGeneINHBC
Homology/Alignments : Family Browser (UCSC)INHBC
Gene fusions - Rearrangements
Fusion : QuiverINHBC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINHBC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INHBC
dbVarINHBC
ClinVarINHBC
1000_GenomesINHBC 
Exome Variant ServerINHBC
ExAC (Exome Aggregation Consortium)ENSG00000175189
GNOMAD BrowserENSG00000175189
Varsome BrowserINHBC
Genetic variants : HAPMAP3626
Genomic Variants (DGV)INHBC [DGVbeta]
DECIPHERINHBC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINHBC 
Mutations
ICGC Data PortalINHBC 
TCGA Data PortalINHBC 
Broad Tumor PortalINHBC
OASIS PortalINHBC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINHBC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINHBC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INHBC
DgiDB (Drug Gene Interaction Database)INHBC
DoCM (Curated mutations)INHBC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INHBC (select a term)
intoGenINHBC
Cancer3DINHBC(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601233   
Orphanet
DisGeNETINHBC
MedgenINHBC
Genetic Testing Registry INHBC
NextProtP55103 [Medical]
TSGene3626
GENETestsINHBC
Target ValidationINHBC
Huge Navigator INHBC [HugePedia]
snp3D : Map Gene to Disease3626
BioCentury BCIQINHBC
ClinGenINHBC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3626
Chemical/Pharm GKB GenePA29879
Clinical trialINHBC
Miscellaneous
canSAR (ICR)INHBC (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINHBC
EVEXINHBC
GoPubMedINHBC
iHOPINHBC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:13:32 CET 2018

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