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INO80 (INO80 complex subunit)

Identity

Alias_namesINOC1
INO80 complex homolog 1 (S. cerevisiae)
INO80 homolog (S. cerevisiae)
Alias_symbol (synonym)KIAA1259
Ino80
hINO80
INO80A
Other alias
HGNC (Hugo) INO80
LocusID (NCBI) 54617
Atlas_Id 46976
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 40978881 and ends at 41116246 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
INO80 (15q15.1) / INO80 (15q15.1)INO80 (15q15.1) / PDE6B (4p16.3)INO80 (15q15.1) / PRKCA (17q24.2)
JMJD1C (10q21.3) / INO80 (15q15.1)NXN (17p13.3) / INO80 (15q15.1)PDE6B (4p16.3) / INO80 (15q15.1)
TMBIM4 (12q14.3) / INO80 (15q15.1)INO80 15q15.1 / PRKCA 17q24.2TMBIM4 12q14.3 / INO80 15q15.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INO80   26956
Cards
Entrez_Gene (NCBI)INO80  54617  INO80 complex subunit
AliasesINO80A; INOC1; hINO80
GeneCards (Weizmann)INO80
Ensembl hg19 (Hinxton)ENSG00000128908 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128908 [Gene_View]  chr15:40978881-41116246 [Contig_View]  INO80 [Vega]
ICGC DataPortalENSG00000128908
TCGA cBioPortalINO80
AceView (NCBI)INO80
Genatlas (Paris)INO80
WikiGenes54617
SOURCE (Princeton)INO80
Genetics Home Reference (NIH)INO80
Genomic and cartography
GoldenPath hg38 (UCSC)INO80  -     chr15:40978881-41116246 -  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INO80  -     15q15.1   [Description]    (hg19-Feb_2009)
EnsemblINO80 - 15q15.1 [CytoView hg19]  INO80 - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIINO80 [Mapview hg19]  INO80 [Mapview hg38]
OMIM610169   
Gene and transcription
Genbank (Entrez)AB033085 AK002176 AK024777 AK026050 AK057582
RefSeq transcript (Entrez)NM_017553 NM_032196
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INO80
Cluster EST : UnigeneHs.292949 [ NCBI ]
CGAP (NCI)Hs.292949
Alternative Splicing GalleryENSG00000128908
Gene ExpressionINO80 [ NCBI-GEO ]   INO80 [ EBI - ARRAY_EXPRESS ]   INO80 [ SEEK ]   INO80 [ MEM ]
Gene Expression Viewer (FireBrowse)INO80 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54617
GTEX Portal (Tissue expression)INO80
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULG1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULG1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULG1
Splice isoforms : SwissVarQ9ULG1
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.123.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
PhosPhoSitePlusQ9ULG1
Domaine pattern : Prosite (Expaxy)DBINO (PS51413)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DBINO    Helicase_ATP-bd    Helicase_C    Ino80    P-loop_NTPase    SNF2_N   
Domain families : Pfam (Sanger)DBINO (PF13892)    Helicase_C (PF00271)    SNF2_N (PF00176)   
Domain families : Pfam (NCBI)pfam13892    pfam00271    pfam00176   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)INO80
DMDM Disease mutations54617
Blocks (Seattle)INO80
SuperfamilyQ9ULG1
Human Protein AtlasENSG00000128908
Peptide AtlasQ9ULG1
HPRD10024
IPIIPI00008091   IPI00423412   IPI00470705   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULG1
IntAct (EBI)Q9ULG1
FunCoupENSG00000128908
BioGRIDINO80
STRING (EMBL)INO80
ZODIACINO80
Ontologies - Pathways
QuickGOQ9ULG1
Ontology : AmiGOmitotic sister chromatid segregation  double-strand break repair via homologous recombination  DNA binding  DNA helicase activity  actin binding  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  microtubule  plasma membrane  double-strand break repair  chromatin remodeling  transcription, DNA-templated  positive regulation of nuclear cell cycle DNA replication  protein deubiquitination  nuclear body  ATPase activity  positive regulation of cell growth  Ino80 complex  DNA duplex unwinding  cellular response to UV  alpha-tubulin binding  intermediate filament cytoskeleton  positive regulation of transcription from RNA polymerase II promoter  spindle assembly  cell division  UV-damage excision repair  cellular response to ionizing radiation  regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBImitotic sister chromatid segregation  double-strand break repair via homologous recombination  DNA binding  DNA helicase activity  actin binding  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  microtubule  plasma membrane  double-strand break repair  chromatin remodeling  transcription, DNA-templated  positive regulation of nuclear cell cycle DNA replication  protein deubiquitination  nuclear body  ATPase activity  positive regulation of cell growth  Ino80 complex  DNA duplex unwinding  cellular response to UV  alpha-tubulin binding  intermediate filament cytoskeleton  positive regulation of transcription from RNA polymerase II promoter  spindle assembly  cell division  UV-damage excision repair  cellular response to ionizing radiation  regulation of G1/S transition of mitotic cell cycle  
NDEx NetworkINO80
Atlas of Cancer Signalling NetworkINO80
Wikipedia pathwaysINO80
Orthology - Evolution
OrthoDB54617
GeneTree (enSembl)ENSG00000128908
Phylogenetic Trees/Animal Genes : TreeFamINO80
HOVERGENQ9ULG1
HOGENOMQ9ULG1
Homologs : HomoloGeneINO80
Homology/Alignments : Family Browser (UCSC)INO80
Gene fusions - Rearrangements
Fusion : MitelmanINO80/PRKCA [15q15.1/17q24.2]  
Fusion : MitelmanTMBIM4/INO80 [12q14.3/15q15.1]  [t(12;15)(q14;q15)]  
Fusion: TCGAINO80 15q15.1 PRKCA 17q24.2 BRCA
Fusion: TCGATMBIM4 12q14.3 INO80 15q15.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINO80 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INO80
dbVarINO80
ClinVarINO80
1000_GenomesINO80 
Exome Variant ServerINO80
ExAC (Exome Aggregation Consortium)INO80 (select the gene name)
Genetic variants : HAPMAP54617
Genomic Variants (DGV)INO80 [DGVbeta]
DECIPHERINO80 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINO80 
Mutations
ICGC Data PortalINO80 
TCGA Data PortalINO80 
Broad Tumor PortalINO80
OASIS PortalINO80 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINO80  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINO80
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INO80
DgiDB (Drug Gene Interaction Database)INO80
DoCM (Curated mutations)INO80 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INO80 (select a term)
intoGenINO80
Cancer3DINO80(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610169   
Orphanet
MedgenINO80
Genetic Testing Registry INO80
NextProtQ9ULG1 [Medical]
TSGene54617
GENETestsINO80
Target ValidationINO80
Huge Navigator INO80 [HugePedia]
snp3D : Map Gene to Disease54617
BioCentury BCIQINO80
ClinGenINO80
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54617
Chemical/Pharm GKB GenePA162392040
Clinical trialINO80
Miscellaneous
canSAR (ICR)INO80 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINO80
EVEXINO80
GoPubMedINO80
iHOPINO80
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:13:23 CEST 2017

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