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INPP1 (inositol polyphosphate-1-phosphatase)

Identity

Other alias-
HGNC (Hugo) INPP1
LocusID (NCBI) 3628
Atlas_Id 43318
Location 2q32.2  [Link to chromosome band 2q32]
Location_base_pair Starts at 190343470 and ends at 190371665 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MFSD6 (2q32.2) / INPP1 (2q32.2)PSMD2 (3q27.1) / INPP1 (2q32.2)TMBIM6 (12q13.12) / INPP1 (2q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INPP1   6071
Cards
Entrez_Gene (NCBI)INPP1  3628  inositol polyphosphate-1-phosphatase
Aliases
GeneCards (Weizmann)INPP1
Ensembl hg19 (Hinxton)ENSG00000151689 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151689 [Gene_View]  chr2:190343470-190371665 [Contig_View]  INPP1 [Vega]
ICGC DataPortalENSG00000151689
TCGA cBioPortalINPP1
AceView (NCBI)INPP1
Genatlas (Paris)INPP1
WikiGenes3628
SOURCE (Princeton)INPP1
Genetics Home Reference (NIH)INPP1
Genomic and cartography
GoldenPath hg38 (UCSC)INPP1  -     chr2:190343470-190371665 +  2q32.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INPP1  -     2q32.2   [Description]    (hg19-Feb_2009)
EnsemblINPP1 - 2q32.2 [CytoView hg19]  INPP1 - 2q32.2 [CytoView hg38]
Mapping of homologs : NCBIINPP1 [Mapview hg19]  INPP1 [Mapview hg38]
OMIM147263   
Gene and transcription
Genbank (Entrez)AB451298 AI680695 AK093560 AW015766 BC015496
RefSeq transcript (Entrez)NM_001128928 NM_002194
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INPP1
Cluster EST : UnigeneHs.32309 [ NCBI ]
CGAP (NCI)Hs.32309
Alternative Splicing GalleryENSG00000151689
Gene ExpressionINPP1 [ NCBI-GEO ]   INPP1 [ EBI - ARRAY_EXPRESS ]   INPP1 [ SEEK ]   INPP1 [ MEM ]
Gene Expression Viewer (FireBrowse)INPP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3628
GTEX Portal (Tissue expression)INPP1
Human Protein AtlasENSG00000151689-INPP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49441   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49441  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49441
Splice isoforms : SwissVarP49441
PhosPhoSitePlusP49441
Domaine pattern : Prosite (Expaxy)IMP_1 (PS00629)    IMP_2 (PS00630)   
Domains : Interpro (EBI)Inositol_monoP_metal-BS    Inositol_monophosphatase-like    Inositol_monophosphatase_CS   
Domain families : Pfam (Sanger)Inositol_P (PF00459)   
Domain families : Pfam (NCBI)pfam00459   
Conserved Domain (NCBI)INPP1
DMDM Disease mutations3628
Blocks (Seattle)INPP1
SuperfamilyP49441
Human Protein Atlas [tissue]ENSG00000151689-INPP1 [tissue]
Peptide AtlasP49441
HPRD00923
IPIIPI00027139   IPI00916305   IPI00916784   IPI00917168   IPI00916959   IPI00917471   IPI00917637   IPI00917527   IPI00917834   IPI00917132   
Protein Interaction databases
DIP (DOE-UCLA)P49441
IntAct (EBI)P49441
FunCoupENSG00000151689
BioGRIDINPP1
STRING (EMBL)INPP1
ZODIACINPP1
Ontologies - Pathways
QuickGOP49441
Ontology : AmiGOinositol-1,4-bisphosphate 1-phosphatase activity  cytosol  phosphate-containing compound metabolic process  signal transduction  dephosphorylation  inositol phosphate metabolic process  phosphatidylinositol phosphorylation  metal ion binding  inositol-1,3,4-trisphosphate 1-phosphatase activity  
Ontology : EGO-EBIinositol-1,4-bisphosphate 1-phosphatase activity  cytosol  phosphate-containing compound metabolic process  signal transduction  dephosphorylation  inositol phosphate metabolic process  phosphatidylinositol phosphorylation  metal ion binding  inositol-1,3,4-trisphosphate 1-phosphatase activity  
Pathways : KEGGInositol phosphate metabolism    Phosphatidylinositol signaling system   
NDEx NetworkINPP1
Atlas of Cancer Signalling NetworkINPP1
Wikipedia pathwaysINPP1
Orthology - Evolution
OrthoDB3628
GeneTree (enSembl)ENSG00000151689
Phylogenetic Trees/Animal Genes : TreeFamINPP1
HOVERGENP49441
HOGENOMP49441
Homologs : HomoloGeneINPP1
Homology/Alignments : Family Browser (UCSC)INPP1
Gene fusions - Rearrangements
Tumor Fusion PortalINPP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINPP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INPP1
dbVarINPP1
ClinVarINPP1
1000_GenomesINPP1 
Exome Variant ServerINPP1
ExAC (Exome Aggregation Consortium)ENSG00000151689
GNOMAD BrowserENSG00000151689
Genetic variants : HAPMAP3628
Genomic Variants (DGV)INPP1 [DGVbeta]
DECIPHERINPP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINPP1 
Mutations
ICGC Data PortalINPP1 
TCGA Data PortalINPP1 
Broad Tumor PortalINPP1
OASIS PortalINPP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINPP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINPP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INPP1
DgiDB (Drug Gene Interaction Database)INPP1
DoCM (Curated mutations)INPP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INPP1 (select a term)
intoGenINPP1
Cancer3DINPP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147263   
Orphanet
DisGeNETINPP1
MedgenINPP1
Genetic Testing Registry INPP1
NextProtP49441 [Medical]
TSGene3628
GENETestsINPP1
Target ValidationINPP1
Huge Navigator INPP1 [HugePedia]
snp3D : Map Gene to Disease3628
BioCentury BCIQINPP1
ClinGenINPP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3628
Chemical/Pharm GKB GenePA29880
Clinical trialINPP1
Miscellaneous
canSAR (ICR)INPP1 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINPP1
EVEXINPP1
GoPubMedINPP1
iHOPINPP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:41:24 CET 2017

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