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INPP4B (inositol polyphosphate-4-phosphatase, type II, 105kDa)

Identity

Other names-
HGNC (Hugo) INPP4B
LocusID (NCBI) 8821
Location 4q31.21
Location_base_pair Starts at 142949182 and ends at 143767604 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)INPP4B   6075
Entrez_Gene (NCBI)INPP4B  8821  inositol polyphosphate-4-phosphatase, type II, 105kDa
Cards
GeneCards (Weizmann)INPP4B
Ensembl (Hinxton)ENSG00000109452 [Gene_View]  chr4:142949182-143767604 [Contig_View]  INPP4B [Vega]
AceView (NCBI)INPP4B
Genatlas (Paris)INPP4B
SOURCE (Stanford)NM_001101669 NM_003866
Genomic and cartography
GoldenPath (UCSC)INPP4B  -  4q31.21   chr4:142949182-143767604 -  4q31.21   [Description]    (hg19-Feb_2009)
EnsemblINPP4B - 4q31.21 [CytoView]
Mapping of homologs : NCBIINPP4B [Mapview]
OMIM607494   
Gene and transcription
Genbank (Entrez)AK298118 AK300891 AK302936 AY753912 BC005273
RefSeq transcript (SRS)NM_001101669 NM_003866
RefSeq transcript (Entrez)NM_001101669 NM_003866
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838921 NW_004078021
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838921 NW_004078021
Consensus coding sequences : CCDS (NCBI)INPP4B
Cluster EST : UnigeneHs.531403 [ SRS ] Hs.531403 [ NCBI ]
CGAP (NCI)Hs.531403
Alternative Splicing : Fast-db (Paris)GSHG0023553
Alternative Splicing GalleryENSG00000109452
Gene ExpressionINPP4B [ NCBI-GEO ]   INPP4B [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15327 (SRS) O15327 (Uniprot)
NextProtO15327
With graphics : InterProO15327
Splice isoforms : SwissVarO15327(Swissvar)
Domaine pattern : Prosite (SRS)C2 (PS50004)   
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (SRS)C2_Ca/lipid-bd_dom_CaLB   
Domains : Interpro (EBI)C2_Ca/lipid-bd_dom_CaLB   
Related proteins : CluSTrO15327
Domain families : Pfam (SRS)
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM8821
Blocks (Seattle)O15327
Human Protein AtlasENSG00000109452
HPRD06322
IPIIPI00022020   IPI00963837   IPI00922726   IPI00965101   IPI00964458   IPI00968221   IPI00029309   IPI00963881   IPI00966726   IPI00967550   IPI00968243   IPI00965363   IPI00965796   
Protein Interaction databases
DIP (DOE-UCLA)O15327
IntAct (EBI)O15327
FunCoupENSG00000109452
REACTOMEINPP4B
Protein Interaction Database8821
BioGRIDINPP4B
InParanoidO15327
Interologous Interaction database O15327
IntegromeDBINPP4B
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)INPP4B
SNP (GeneSNP Utah)INPP4B
SNP : HGBaseINPP4B
Genetic variants : HAPMAPINPP4B
Somatic Mutations in Cancer : COSMICINPP4B 
CONAN: Copy Number AnalysisINPP4B 
Mutations and Diseases : HGMDINPP4B
OMIM607494   
GENETests607494   
Disease Genetic AssociationINPP4B
Huge Navigator INPP4B [HugePedia]  INPP4B [HugeCancerGEM]
Genomic VariantsINPP4B  INPP4B [DGVbeta]
snp3D : Map Gene to Disease8821
General knowledge
Homologs : HomoloGeneINPP4B
Homology/Alignments : Family Browser (UCSC)INPP4B
Phylogenetic Trees/Animal Genes : TreeFamINPP4B
Catalytic activity : Enzyme3.1.3.66 [ Enzyme-Expasy ]   3.1.3.66 [ Enzyme-SRS ]   3.1.3.66 [ IntEnz-EBI ]   3.1.3.66 [ BRENDA ]   3.1.3.66 [ KEGG ]   
Chemical/Protein Interactions : CTD8821
Chemical/Pharm GKB GenePA29883
Clinical trialINPP4B
Cancer Resource (Charite)ENSG00000109452
Ontology : AmiGOcytosol  phospholipid metabolic process  phosphatidylinositol biosynthetic process  signal transduction  phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity  phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity  phosphatidylinositol-3-phosphate biosynthetic process  small molecule metabolic process  
Ontology : EGO-EBIcytosol  phospholipid metabolic process  phosphatidylinositol biosynthetic process  signal transduction  phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity  phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity  phosphatidylinositol-3-phosphate biosynthetic process  small molecule metabolic process  
Pathways : KEGGInositol phosphate metabolismPhosphatidylinositol signaling system
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
PubGeneINPP4B
iHOPINPP4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:47:53 CEST 2013

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