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INPP5A (inositol polyphosphate-5-phosphatase, 40kDa)

Identity

Other names5PTASE
HGNC (Hugo) INPP5A
LocusID (NCBI) 3632
Location 10q26.3
Location_base_pair Starts at 134351353 and ends at 134596984 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)INPP5A   6076
Cards
Entrez_Gene (NCBI)INPP5A  3632  inositol polyphosphate-5-phosphatase, 40kDa
GeneCards (Weizmann)INPP5A
Ensembl (Hinxton)ENSG00000068383 [Gene_View]  chr10:134351353-134596984 [Contig_View]  INPP5A [Vega]
ICGC DataPortalENSG00000068383
cBioPortalINPP5A
AceView (NCBI)INPP5A
Genatlas (Paris)INPP5A
WikiGenes3632
SOURCE (Princeton)NM_005539
Genomic and cartography
GoldenPath (UCSC)INPP5A  -  10q26.3   chr10:134351353-134596984 +  10q26.3   [Description]    (hg19-Feb_2009)
EnsemblINPP5A - 10q26.3 [CytoView]
Mapping of homologs : NCBIINPP5A [Mapview]
OMIM600106   
Gene and transcription
Genbank (Entrez)AF273055 BC052265 BC062300 BC096280 BC096281
RefSeq transcript (Entrez)NM_005539
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838014 NW_004929377
Consensus coding sequences : CCDS (NCBI)INPP5A
Cluster EST : UnigeneHs.715308 [ NCBI ]
CGAP (NCI)Hs.715308
Alternative Splicing : Fast-db (Paris)GSHG0003798
Alternative Splicing GalleryENSG00000068383
Gene ExpressionINPP5A [ NCBI-GEO ]     INPP5A [ SEEK ]   INPP5A [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14642 (Uniprot)
NextProtQ14642  [Medical]
With graphics : InterProQ14642
Splice isoforms : SwissVarQ14642 (Swissvar)
Catalytic activity : Enzyme3.1.3.56 [ Enzyme-Expasy ]   3.1.3.563.1.3.56 [ IntEnz-EBI ]   3.1.3.56 [ BRENDA ]   3.1.3.56 [ KEGG ]   
Domains : Interpro (EBI)Endo/exonuclease/phosphatase [organisation]   IPPc [organisation]  
Related proteins : CluSTrQ14642
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Domain families : Smart (EMBL)IPPc (SM00128)  
DMDM Disease mutations3632
Blocks (Seattle)Q14642
Human Protein AtlasENSG00000068383 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ14642
HPRD02521
IPIIPI00032262   IPI00514660   IPI00384273   IPI00514460   IPI01010770   IPI00413212   IPI00552455   
Protein Interaction databases
DIP (DOE-UCLA)Q14642
IntAct (EBI)Q14642
FunCoupENSG00000068383
BioGRIDINPP5A
InParanoidQ14642
Interologous Interaction database Q14642
IntegromeDBINPP5A
STRING (EMBL)INPP5A
Ontologies - Pathways
Ontology : AmiGOinositol-polyphosphate 5-phosphatase activity  protein binding  plasma membrane  membrane  PH domain binding  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  extracellular vesicular exosome  
Ontology : EGO-EBIinositol-polyphosphate 5-phosphatase activity  protein binding  plasma membrane  membrane  PH domain binding  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  extracellular vesicular exosome  
Pathways : KEGGInositol phosphate metabolism    Phosphatidylinositol signaling system   
Protein Interaction DatabaseINPP5A
Wikipedia pathwaysINPP5A
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)INPP5A
snp3D : Map Gene to Disease3632
SNP (GeneSNP Utah)INPP5A
SNP : HGBaseINPP5A
Genetic variants : HAPMAPINPP5A
Exome VariantINPP5A
1000_GenomesINPP5A 
ICGC programENSG00000068383 
Somatic Mutations in Cancer : COSMICINPP5A 
CONAN: Copy Number AnalysisINPP5A 
Mutations and Diseases : HGMDINPP5A
Genomic VariantsINPP5A  INPP5A [DGVbeta]
dbVarINPP5A
ClinVarINPP5A
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM600106   
MedgenINPP5A
GENETestsINPP5A
Disease Genetic AssociationINPP5A
Huge Navigator INPP5A [HugePedia]  INPP5A [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneINPP5A
Homology/Alignments : Family Browser (UCSC)INPP5A
Phylogenetic Trees/Animal Genes : TreeFamINPP5A
Chemical/Protein Interactions : CTD3632
Chemical/Pharm GKB GenePA29884
Clinical trialINPP5A
Cancer Resource (Charite)ENSG00000068383
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
CoreMineINPP5A
iHOPINPP5A
OncoSearchINPP5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:35:25 CEST 2014

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