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INPP5F (inositol polyphosphate-5-phosphatase F)

Identity

Alias (NCBI)MSTP007
MSTPO47
SAC2
hSAC2
HGNC (Hugo) INPP5F
HGNC Alias symbSAC2
KIAA0966
hSac2
LocusID (NCBI) 22876
Atlas_Id 43324
Location 10q26.11  [Link to chromosome band 10q26]
Location_base_pair Starts at 119726050 and ends at 119829147 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
INPP5F (10q26.11) / INPP5F (10q26.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)INPP5F   17054
LRG (Locus Reference Genomic)LRG_1061
Cards
Entrez_Gene (NCBI)INPP5F    inositol polyphosphate-5-phosphatase F
AliasesMSTP007; MSTPO47; SAC2; hSAC2
GeneCards (Weizmann)INPP5F
Ensembl hg19 (Hinxton)ENSG00000198825 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198825 [Gene_View]  ENSG00000198825 [Sequence]  chr10:119726050-119829147 [Contig_View]  INPP5F [Vega]
ICGC DataPortalENSG00000198825
TCGA cBioPortalINPP5F
AceView (NCBI)INPP5F
Genatlas (Paris)INPP5F
SOURCE (Princeton)INPP5F
Genetics Home Reference (NIH)INPP5F
Genomic and cartography
GoldenPath hg38 (UCSC)INPP5F  -     chr10:119726050-119829147 +  10q26.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INPP5F  -     10q26.11   [Description]    (hg19-Feb_2009)
GoldenPathINPP5F - 10q26.11 [CytoView hg19]  INPP5F - 10q26.11 [CytoView hg38]
ImmunoBaseENSG00000198825
genome Data Viewer NCBIINPP5F [Mapview hg19]  
OMIM609389   
Gene and transcription
Genbank (Entrez)AB023183 AF109361 AF113227 AI492073 AI783668
RefSeq transcript (Entrez)NM_001243194 NM_001243195 NM_014937
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INPP5F
Alternative Splicing GalleryENSG00000198825
Gene ExpressionINPP5F [ NCBI-GEO ]   INPP5F [ EBI - ARRAY_EXPRESS ]   INPP5F [ SEEK ]   INPP5F [ MEM ]
Gene Expression Viewer (FireBrowse)INPP5F [ Firebrowse - Broad ]
GenevisibleExpression of INPP5F in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22876
GTEX Portal (Tissue expression)INPP5F
Human Protein AtlasENSG00000198825-INPP5F [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2H2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2H2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2H2
Splice isoforms : SwissVarQ9Y2H2
PhosPhoSitePlusQ9Y2H2
Domaine pattern : Prosite (Expaxy)HSAC2 (PS51791)    SAC (PS50275)   
Domains : Interpro (EBI)hSac2    Inositol_phosphatase    SAC_dom   
Domain families : Pfam (Sanger)hSac2 (PF12456)    Syja_N (PF02383)   
Domain families : Pfam (NCBI)pfam12456    pfam02383   
Conserved Domain (NCBI)INPP5F
Blocks (Seattle)INPP5F
PDB (RSDB)4XUU   
PDB Europe4XUU   
PDB (PDBSum)4XUU   
PDB (IMB)4XUU   
Structural Biology KnowledgeBase4XUU   
SCOP (Structural Classification of Proteins)4XUU   
CATH (Classification of proteins structures)4XUU   
SuperfamilyQ9Y2H2
Human Protein Atlas [tissue]ENSG00000198825-INPP5F [tissue]
Peptide AtlasQ9Y2H2
HPRD11048
IPIIPI00480159   IPI00890685   IPI00890735   IPI00383580   IPI00384184   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2H2
IntAct (EBI)Q9Y2H2
BioGRIDINPP5F
STRING (EMBL)INPP5F
ZODIACINPP5F
Ontologies - Pathways
QuickGOQ9Y2H2
Ontology : AmiGOpositive regulation of receptor recycling  protein binding  early endosome  early endosome  clathrin-coated pit  phosphatidylinositol biosynthetic process  adult locomotory behavior  inositol monophosphate 1-phosphatase activity  cardiac muscle hypertrophy in response to stress  axon  dendrite  phosphatidylinositol catabolic process  early endosome membrane  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol phosphate 5-phosphatase activity  phosphatidylinositol phosphate 5-phosphatase activity  phosphatidylinositol phosphate 4-phosphatase activity  phosphatidylinositol phosphate 4-phosphatase activity  negative regulation of tyrosine phosphorylation of STAT protein  protein homodimerization activity  neuronal cell body  intracellular membrane-bounded organelle  phosphatidylinositol-4-phosphate phosphatase activity  clathrin-coated endocytic vesicle  clathrin-coated endocytic vesicle  phosphatidylinositol dephosphorylation  phosphatidylinositol dephosphorylation  phosphatidylinositol-mediated signaling  negative regulation of axon regeneration  regulation of protein kinase B signaling  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  recycling endosome  clathrin-dependent endocytosis  regulation of cell motility  regulation of endocytic recycling  regulation of endocytic recycling  
Ontology : EGO-EBIpositive regulation of receptor recycling  protein binding  early endosome  early endosome  clathrin-coated pit  phosphatidylinositol biosynthetic process  adult locomotory behavior  inositol monophosphate 1-phosphatase activity  cardiac muscle hypertrophy in response to stress  axon  dendrite  phosphatidylinositol catabolic process  early endosome membrane  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol phosphate 5-phosphatase activity  phosphatidylinositol phosphate 5-phosphatase activity  phosphatidylinositol phosphate 4-phosphatase activity  phosphatidylinositol phosphate 4-phosphatase activity  negative regulation of tyrosine phosphorylation of STAT protein  protein homodimerization activity  neuronal cell body  intracellular membrane-bounded organelle  phosphatidylinositol-4-phosphate phosphatase activity  clathrin-coated endocytic vesicle  clathrin-coated endocytic vesicle  phosphatidylinositol dephosphorylation  phosphatidylinositol dephosphorylation  phosphatidylinositol-mediated signaling  negative regulation of axon regeneration  regulation of protein kinase B signaling  inositol monophosphate 3-phosphatase activity  inositol monophosphate 4-phosphatase activity  recycling endosome  clathrin-dependent endocytosis  regulation of cell motility  regulation of endocytic recycling  regulation of endocytic recycling  
NDEx NetworkINPP5F
Atlas of Cancer Signalling NetworkINPP5F
Wikipedia pathwaysINPP5F
Orthology - Evolution
OrthoDB22876
GeneTree (enSembl)ENSG00000198825
Phylogenetic Trees/Animal Genes : TreeFamINPP5F
HOGENOMQ9Y2H2
Homologs : HomoloGeneINPP5F
Homology/Alignments : Family Browser (UCSC)INPP5F
Gene fusions - Rearrangements
Fusion : QuiverINPP5F
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINPP5F [hg38]
dbVarINPP5F
ClinVarINPP5F
MonarchINPP5F
1000_GenomesINPP5F 
Exome Variant ServerINPP5F
GNOMAD BrowserENSG00000198825
Varsome BrowserINPP5F
Genomic Variants (DGV)INPP5F [DGVbeta]
DECIPHERINPP5F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINPP5F 
Mutations
ICGC Data PortalINPP5F 
TCGA Data PortalINPP5F 
Broad Tumor PortalINPP5F
OASIS PortalINPP5F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINPP5F  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DINPP5F
Mutations and Diseases : HGMDINPP5F
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INPP5F
DgiDB (Drug Gene Interaction Database)INPP5F
DoCM (Curated mutations)INPP5F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INPP5F (select a term)
intoGenINPP5F
Cancer3DINPP5F(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609389   
Orphanet
DisGeNETINPP5F
MedgenINPP5F
Genetic Testing Registry INPP5F
NextProtQ9Y2H2 [Medical]
GENETestsINPP5F
Target ValidationINPP5F
Huge Navigator INPP5F [HugePedia]
ClinGenINPP5F
Clinical trials, drugs, therapy
MyCancerGenomeINPP5F
Protein Interactions : CTD
Pharm GKB GenePA134927878
PharosQ9Y2H2
Clinical trialINPP5F
Miscellaneous
canSAR (ICR)INPP5F (select the gene name)
HarmonizomeINPP5F
DataMed IndexINPP5F
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXINPP5F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:20:23 CET 2021

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