INPP5F (inositol polyphosphate-5-phosphatase F)

2006-10-01  

Identity

HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
MSTP007,MSTPO47,SAC2,hSAC2
FUSION GENES

Other Information

Locus ID:

NCBI: 22876
MIM: 609389
HGNC: 17054
Ensembl: ENSG00000198825

Variants:

dbSNP: 22876
ClinVar: 22876
TCGA: ENSG00000198825
COSMIC: INPP5F

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198825ENST00000369081Q9Y2H2
ENSG00000198825ENST00000490818A0A0J9YVW6
ENSG00000198825ENST00000631485A0A0J9YWP2
ENSG00000198825ENST00000631555A0A0J9YYL5
ENSG00000198825ENST00000631572A0A0J9YY79
ENSG00000198825ENST00000637174A0A1B0GUS5
ENSG00000198825ENST00000647699A0A3B3ITL0
ENSG00000198825ENST00000647933A0A3B3ISK0
ENSG00000198825ENST00000648262A0A3B3IRJ9
ENSG00000198825ENST00000648515A0A3B3IRT4
ENSG00000198825ENST00000648621A0A3B3IS29
ENSG00000198825ENST00000648661A0A3B3ISG0
ENSG00000198825ENST00000649251A0A3B3ISI3
ENSG00000198825ENST00000649297A0A3B3IU10
ENSG00000198825ENST00000649454A0A3B3ITL0
ENSG00000198825ENST00000649742A0A3B3ISJ5
ENSG00000198825ENST00000649957A0A3B3ITR9
ENSG00000198825ENST00000650305A0A3B3IS98
ENSG00000198825ENST00000650409Q9Y2H2
ENSG00000198825ENST00000650623Q9Y2H2

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the early endosome membraneREACTOMER-HSA-1660516

References

Pubmed IDYearTitleCitations
358480212022Parkinson's Disease rs117896735 Variant Regulates INPP5F Expression in Brain Tissues and Increases Risk of Alzheimer's Disease.2
358480212022Parkinson's Disease rs117896735 Variant Regulates INPP5F Expression in Brain Tissues and Increases Risk of Alzheimer's Disease.2
326934312020Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations.7
326934312020Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations.7
258696692015Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling.35
264307242015Gene expression of INPP5F as an independent prognostic marker in fludarabine-based therapy of chronic lymphocytic leukemia.5
258696692015Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling.35
264307242015Gene expression of INPP5F as an independent prognostic marker in fludarabine-based therapy of chronic lymphocytic leukemia.5
254764552014Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.13
254764552014Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.13
198757262009Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness.38
198757262009Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness.38
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

INPP5F (inositol polyphosphate-5-phosphatase F)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43324/inpp5f