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INS (insulin)

Identity

Other names-
HGNC INS
Location 11p15.5
Location_base_pair Starts at 2137585 and ends at 2139015 bp from pter ( according to hg18-March_2006).
Note

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNCINS   6081
Entrez_GeneINS  3630  insulin
Cards
GeneCardsINS
EnsemblINS [Search_View]   ENSG00000129965 [Gene_View]
GenatlasINS
GeneLynxINS
eGenomeINS
euGene3630
Genomic and cartography
GoldenPathINS  -  11p15.5   chr11:2137585-2139015 -  11p15.5   [Description]    (hg18-March_2006)
EnsemblINS - 11p15.5 [CytoView]
NCBIMapview
OMIMDisease map [OMIM]
HomoloGeneINS
Gene and transcription
GenbankAY899304 [ ENTREZ ]
GenbankBC005255 [ ENTREZ ]
GenbankBM510748 [ ENTREZ ]
GenbankBT006808 [ ENTREZ ]
GenbankDQ893040 [ ENTREZ ]
RefSeqNM_000207 [ SRS ]    NM_000207 [ ENTREZ ]
RefSeqAC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeqAC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeqNC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeqNG_007114 [ SRS ]    NG_007114 [ ENTREZ ]
RefSeqNT_009237 [ SRS ]    NT_009237 [ ENTREZ ]
RefSeqNW_001838018 [ SRS ]    NW_001838018 [ ENTREZ ]
RefSeqNW_924962 [ SRS ]    NW_924962 [ ENTREZ ]
AceViewINS AceView - NCBI
UnigeneHs.523414 [ SRS ]    Hs.523414 [ NCBI ]     HS523414 [ spliceNest ]
Fast-db846 (alternative variants)
Protein : pattern, domain, 3D structure
SwissProtP01308 [ SRS]    P01308 [ EXPASY ]     P01308 [ INTERPRO ]     P01308 [ UNIPROT ]
PrositePS00262 INSULIN [ SRS ]    PS00262 INSULIN [ Expasy ]
InterproIPR004825 Ins/IGF/relaxin [ SRS ]    IPR004825 Ins/IGF/relaxin [ EBI ]
CluSTrP01308
PfamPF00049 Insulin [ SRS ]    PF00049 Insulin [ Sanger ]    pfam00049 [ NCBI-CDD ]
SmartSM00078 IlGF [EMBL]
ProdomPD015667 Mollusc_ins[INRA-Toulouse]
ProdomP01308 INS_HUMAN [ Domain structure ]   P01308 INS_HUMAN  [ sequences sharing at least 1 domain ]
BlocksP01308
PDB1A7F [ SRS ]    1A7F [ PdbSum ],   1A7F [ IMB ]   1A7F [ RSDB ]
PDB1AI0 [ SRS ]    1AI0 [ PdbSum ],   1AI0 [ IMB ]   1AI0 [ RSDB ]
PDB1AIY [ SRS ]    1AIY [ PdbSum ],   1AIY [ IMB ]   1AIY [ RSDB ]
PDB1B9E [ SRS ]    1B9E [ PdbSum ],   1B9E [ IMB ]   1B9E [ RSDB ]
PDB1BEN [ SRS ]    1BEN [ PdbSum ],   1BEN [ IMB ]   1BEN [ RSDB ]
PDB1EFE [ SRS ]    1EFE [ PdbSum ],   1EFE [ IMB ]   1EFE [ RSDB ]
PDB1EV3 [ SRS ]    1EV3 [ PdbSum ],   1EV3 [ IMB ]   1EV3 [ RSDB ]
PDB1EV6 [ SRS ]    1EV6 [ PdbSum ],   1EV6 [ IMB ]   1EV6 [ RSDB ]
PDB1EVR [ SRS ]    1EVR [ PdbSum ],   1EVR [ IMB ]   1EVR [ RSDB ]
PDB1FU2 [ SRS ]    1FU2 [ PdbSum ],   1FU2 [ IMB ]   1FU2 [ RSDB ]
PDB1FUB [ SRS ]    1FUB [ PdbSum ],   1FUB [ IMB ]   1FUB [ RSDB ]
PDB1G7A [ SRS ]    1G7A [ PdbSum ],   1G7A [ IMB ]   1G7A [ RSDB ]
PDB1G7B [ SRS ]    1G7B [ PdbSum ],   1G7B [ IMB ]   1G7B [ RSDB ]
PDB1GUJ [ SRS ]    1GUJ [ PdbSum ],   1GUJ [ IMB ]   1GUJ [ RSDB ]
PDB1HIQ [ SRS ]    1HIQ [ PdbSum ],   1HIQ [ IMB ]   1HIQ [ RSDB ]
PDB1HIS [ SRS ]    1HIS [ PdbSum ],   1HIS [ IMB ]   1HIS [ RSDB ]
PDB1HIT [ SRS ]    1HIT [ PdbSum ],   1HIT [ IMB ]   1HIT [ RSDB ]
PDB1HLS [ SRS ]    1HLS [ PdbSum ],   1HLS [ IMB ]   1HLS [ RSDB ]
PDB1HTV [ SRS ]    1HTV [ PdbSum ],   1HTV [ IMB ]   1HTV [ RSDB ]
PDB1HUI [ SRS ]    1HUI [ PdbSum ],   1HUI [ IMB ]   1HUI [ RSDB ]
PDB1IOG [ SRS ]    1IOG [ PdbSum ],   1IOG [ IMB ]   1IOG [ RSDB ]
PDB1IOH [ SRS ]    1IOH [ PdbSum ],   1IOH [ IMB ]   1IOH [ RSDB ]
PDB1J73 [ SRS ]    1J73 [ PdbSum ],   1J73 [ IMB ]   1J73 [ RSDB ]
PDB1JCA [ SRS ]    1JCA [ PdbSum ],   1JCA [ IMB ]   1JCA [ RSDB ]
PDB1JCO [ SRS ]    1JCO [ PdbSum ],   1JCO [ IMB ]   1JCO [ RSDB ]
PDB1K3M [ SRS ]    1K3M [ PdbSum ],   1K3M [ IMB ]   1K3M [ RSDB ]
PDB1KMF [ SRS ]    1KMF [ PdbSum ],   1KMF [ IMB ]   1KMF [ RSDB ]
PDB1LKQ [ SRS ]    1LKQ [ PdbSum ],   1LKQ [ IMB ]   1LKQ [ RSDB ]
PDB1LPH [ SRS ]    1LPH [ PdbSum ],   1LPH [ IMB ]   1LPH [ RSDB ]
PDB1MHI [ SRS ]    1MHI [ PdbSum ],   1MHI [ IMB ]   1MHI [ RSDB ]
PDB1MHJ [ SRS ]    1MHJ [ PdbSum ],   1MHJ [ IMB ]   1MHJ [ RSDB ]
PDB1MSO [ SRS ]    1MSO [ PdbSum ],   1MSO [ IMB ]   1MSO [ RSDB ]
PDB1OS3 [ SRS ]    1OS3 [ PdbSum ],   1OS3 [ IMB ]   1OS3 [ RSDB ]
PDB1OS4 [ SRS ]    1OS4 [ PdbSum ],   1OS4 [ IMB ]   1OS4 [ RSDB ]
PDB1QIY [ SRS ]    1QIY [ PdbSum ],   1QIY [ IMB ]   1QIY [ RSDB ]
PDB1QIZ [ SRS ]    1QIZ [ PdbSum ],   1QIZ [ IMB ]   1QIZ [ RSDB ]
PDB1QJ0 [ SRS ]    1QJ0 [ PdbSum ],   1QJ0 [ IMB ]   1QJ0 [ RSDB ]
PDB1RWE [ SRS ]    1RWE [ PdbSum ],   1RWE [ IMB ]   1RWE [ RSDB ]
PDB1SF1 [ SRS ]    1SF1 [ PdbSum ],   1SF1 [ IMB ]   1SF1 [ RSDB ]
PDB1SJT [ SRS ]    1SJT [ PdbSum ],   1SJT [ IMB ]   1SJT [ RSDB ]
PDB1SJU [ SRS ]    1SJU [ PdbSum ],   1SJU [ IMB ]   1SJU [ RSDB ]
PDB1T0C [ SRS ]    1T0C [ PdbSum ],   1T0C [ IMB ]   1T0C [ RSDB ]
PDB1T1K [ SRS ]    1T1K [ PdbSum ],   1T1K [ IMB ]   1T1K [ RSDB ]
PDB1T1P [ SRS ]    1T1P [ PdbSum ],   1T1P [ IMB ]   1T1P [ RSDB ]
PDB1T1Q [ SRS ]    1T1Q [ PdbSum ],   1T1Q [ IMB ]   1T1Q [ RSDB ]
PDB1TRZ [ SRS ]    1TRZ [ PdbSum ],   1TRZ [ IMB ]   1TRZ [ RSDB ]
PDB1TYL [ SRS ]    1TYL [ PdbSum ],   1TYL [ IMB ]   1TYL [ RSDB ]
PDB1TYM [ SRS ]    1TYM [ PdbSum ],   1TYM [ IMB ]   1TYM [ RSDB ]
PDB1UZ9 [ SRS ]    1UZ9 [ PdbSum ],   1UZ9 [ IMB ]   1UZ9 [ RSDB ]
PDB1VKT [ SRS ]    1VKT [ PdbSum ],   1VKT [ IMB ]   1VKT [ RSDB ]
PDB1W8P [ SRS ]    1W8P [ PdbSum ],   1W8P [ IMB ]   1W8P [ RSDB ]
PDB1XDA [ SRS ]    1XDA [ PdbSum ],   1XDA [ IMB ]   1XDA [ RSDB ]
PDB1XGL [ SRS ]    1XGL [ PdbSum ],   1XGL [ IMB ]   1XGL [ RSDB ]
PDB1XW7 [ SRS ]    1XW7 [ PdbSum ],   1XW7 [ IMB ]   1XW7 [ RSDB ]
PDB1ZEG [ SRS ]    1ZEG [ PdbSum ],   1ZEG [ IMB ]   1ZEG [ RSDB ]
PDB1ZEH [ SRS ]    1ZEH [ PdbSum ],   1ZEH [ IMB ]   1ZEH [ RSDB ]
PDB1ZNJ [ SRS ]    1ZNJ [ PdbSum ],   1ZNJ [ IMB ]   1ZNJ [ RSDB ]
PDB2AIY [ SRS ]    2AIY [ PdbSum ],   2AIY [ IMB ]   2AIY [ RSDB ]
PDB2C8Q [ SRS ]    2C8Q [ PdbSum ],   2C8Q [ IMB ]   2C8Q [ RSDB ]
PDB2C8R [ SRS ]    2C8R [ PdbSum ],   2C8R [ IMB ]   2C8R [ RSDB ]
PDB2CEU [ SRS ]    2CEU [ PdbSum ],   2CEU [ IMB ]   2CEU [ RSDB ]
PDB2H67 [ SRS ]    2H67 [ PdbSum ],   2H67 [ IMB ]   2H67 [ RSDB ]
PDB2HH4 [ SRS ]    2HH4 [ PdbSum ],   2HH4 [ IMB ]   2HH4 [ RSDB ]
PDB2HHO [ SRS ]    2HHO [ PdbSum ],   2HHO [ IMB ]   2HHO [ RSDB ]
PDB2HIU [ SRS ]    2HIU [ PdbSum ],   2HIU [ IMB ]   2HIU [ RSDB ]
PDB2JMN [ SRS ]    2JMN [ PdbSum ],   2JMN [ IMB ]   2JMN [ RSDB ]
PDB2JV1 [ SRS ]    2JV1 [ PdbSum ],   2JV1 [ IMB ]   2JV1 [ RSDB ]
PDB2JZQ [ SRS ]    2JZQ [ PdbSum ],   2JZQ [ IMB ]   2JZQ [ RSDB ]
PDB2OLY [ SRS ]    2OLY [ PdbSum ],   2OLY [ IMB ]   2OLY [ RSDB ]
PDB2OLZ [ SRS ]    2OLZ [ PdbSum ],   2OLZ [ IMB ]   2OLZ [ RSDB ]
PDB2OM0 [ SRS ]    2OM0 [ PdbSum ],   2OM0 [ IMB ]   2OM0 [ RSDB ]
PDB2OM1 [ SRS ]    2OM1 [ PdbSum ],   2OM1 [ IMB ]   2OM1 [ RSDB ]
PDB2OMG [ SRS ]    2OMG [ PdbSum ],   2OMG [ IMB ]   2OMG [ RSDB ]
PDB2OMH [ SRS ]    2OMH [ PdbSum ],   2OMH [ IMB ]   2OMH [ RSDB ]
PDB2OMI [ SRS ]    2OMI [ PdbSum ],   2OMI [ IMB ]   2OMI [ RSDB ]
PDB2QIU [ SRS ]    2QIU [ PdbSum ],   2QIU [ IMB ]   2QIU [ RSDB ]
PDB3AIY [ SRS ]    3AIY [ PdbSum ],   3AIY [ IMB ]   3AIY [ RSDB ]
PDB4AIY [ SRS ]    4AIY [ PdbSum ],   4AIY [ IMB ]   4AIY [ RSDB ]
PDB5AIY [ SRS ]    5AIY [ PdbSum ],   5AIY [ IMB ]   5AIY [ RSDB ]
HPRD01455
Protein Interaction databases
DIPP01308
IntActP01308
Polymorphism : SNP, mutations, diseases
OMIM125850;176730    [ map ]   
GENECLINICS125850;176730
SNPINS [dbSNP-NCBI]  
SNPNM_000207 [SNP-NCI]  
SNPINS [GeneSNPs - Utah]  INS] [HGBASE - SRS]
HAPMAPINS [HAPMAP]  
HGMDINS
General knowledge
Family BrowserINS [UCSC Family Browser]
SOURCENM_000207
SMDHs.523414
SAGEHs.523414
GOnegative regulation of acute inflammatory response [Amigo]  negative regulation of acute inflammatory response
GOinsulin receptor binding [Amigo]  insulin receptor binding
GOinsulin-like growth factor receptor binding [Amigo]  insulin-like growth factor receptor binding
GOhormone activity [Amigo]  hormone activity
GOprotein binding [Amigo]  protein binding
GOinsulin-like growth factor binding [Amigo]  insulin-like growth factor binding
GOextracellular region [Amigo]  extracellular region
GOextracellular space [Amigo]  extracellular space
GOcarbohydrate metabolic process [Amigo]  carbohydrate metabolic process
GOglucose metabolic process [Amigo]  glucose metabolic process
GOregulation of amino acid metabolic process [Amigo]  regulation of amino acid metabolic process
GOacute-phase response [Amigo]  acute-phase response
GOG-protein coupled receptor protein signaling pathway [Amigo]  G-protein coupled receptor protein signaling pathway
GOcell-cell signaling [Amigo]  cell-cell signaling
GOcell death [Amigo]  cell death
GOnegative regulation of metabolic process [Amigo]  negative regulation of metabolic process
GOpositive regulation of metabolic process [Amigo]  positive regulation of metabolic process
GOphosphoinositide 3-kinase cascade [Amigo]  phosphoinositide 3-kinase cascade
GOglucose transport [Amigo]  glucose transport
GOregulation of transmembrane transporter activity [Amigo]  regulation of transmembrane transporter activity
GOpositive regulation of cellular protein metabolic process [Amigo]  positive regulation of cellular protein metabolic process
GOregulation of gene-specific transcription [Amigo]  regulation of gene-specific transcription
GOregulation of protein localization [Amigo]  regulation of protein localization
GOnegative regulation of NAD(P)H oxidase activity [Amigo]  negative regulation of NAD(P)H oxidase activity
GOwound healing [Amigo]  wound healing
GOnegative regulation of protein catabolic process [Amigo]  negative regulation of protein catabolic process
GOglucose homeostasis [Amigo]  glucose homeostasis
GOpositive regulation of nitric oxide biosynthetic process [Amigo]  positive regulation of nitric oxide biosynthetic process
GOrespiratory burst [Amigo]  respiratory burst
GOpositive regulation of DNA replication [Amigo]  positive regulation of DNA replication
GOnegative regulation of glycogen catabolic process [Amigo]  negative regulation of glycogen catabolic process
GOpositive regulation of glycolysis [Amigo]  positive regulation of glycolysis
GOpositive regulation of glycolysis [Amigo]  positive regulation of glycolysis
GOnegative regulation of proteolysis [Amigo]  negative regulation of proteolysis
GOnegative regulation of vasodilation [Amigo]  negative regulation of vasodilation
GOpositive regulation of vasodilation [Amigo]  positive regulation of vasodilation
GOnegative regulation of fatty acid metabolic process [Amigo]  negative regulation of fatty acid metabolic process
GOpositive regulation of glucose import [Amigo]  positive regulation of glucose import
GOpositive regulation of insulin receptor signaling pathway [Amigo]  positive regulation of insulin receptor signaling pathway
GOalpha-beta T cell activation [Amigo]  alpha-beta T cell activation
GOnegative regulation of protein secretion [Amigo]  negative regulation of protein secretion
GOpositive regulation of cytokine secretion [Amigo]  positive regulation of cytokine secretion
GOpositive regulation of nitric-oxide synthase activity [Amigo]  positive regulation of nitric-oxide synthase activity
GOfatty acid homeostasis [Amigo]  fatty acid homeostasis
BIOCARTAGrowth Hormone Signaling Pathway    [Genes]
BIOCARTAControl of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK)    [Genes]
BIOCARTAInsulin Signaling Pathway    [Genes]
BIOCARTAMechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)    [Genes]
KEGGRegulation of autophagy
KEGGmTOR signaling pathway
KEGGRegulation of actin cytoskeleton
KEGGInsulin signaling pathway
KEGGType II diabetes mellitus
KEGGType I diabetes mellitus
KEGGMaturity onset diabetes of the young
KEGGDentatorubropallidoluysian atrophy (DRPLA)
PubGeneINS
TreeFamINS
CTD3630 [Comparative ToxicoGenomics Database]
Other databases
Probes
ProbeINS Related clones (RZPD - Berlin)
PubMed
PubMed335 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2008Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Oct 18 14:46:46 2008


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