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INSC (inscuteable homolog (Drosophila))

Identity

Other alias-
HGNC (Hugo) INSC
LocusID (NCBI) 387755
Atlas_Id 64622
Location 11p15.2  [Link to chromosome band 11p15]
Location_base_pair Starts at 15112424 and ends at 15247208 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GLB1 (3p22.3) / INSC (11p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INSC   33116
Cards
Entrez_Gene (NCBI)INSC  387755  inscuteable homolog (Drosophila)
Aliases
GeneCards (Weizmann)INSC
Ensembl hg19 (Hinxton)ENSG00000188487 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188487 [Gene_View]  chr11:15112424-15247208 [Contig_View]  INSC [Vega]
ICGC DataPortalENSG00000188487
TCGA cBioPortalINSC
AceView (NCBI)INSC
Genatlas (Paris)INSC
WikiGenes387755
SOURCE (Princeton)INSC
Genetics Home Reference (NIH)INSC
Genomic and cartography
GoldenPath hg38 (UCSC)INSC  -     chr11:15112424-15247208 +  11p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INSC  -     11p15.2   [Description]    (hg19-Feb_2009)
EnsemblINSC - 11p15.2 [CytoView hg19]  INSC - 11p15.2 [CytoView hg38]
Mapping of homologs : NCBIINSC [Mapview hg19]  INSC [Mapview hg38]
OMIM610668   
Gene and transcription
Genbank (Entrez)AB231744 AB231745 AB231746 AB231747 AB231748
RefSeq transcript (Entrez)NM_001031853 NM_001042536 NM_001278313 NM_001278314 NM_001278315 NM_001278316
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INSC
Cluster EST : UnigeneHs.591997 [ NCBI ]
CGAP (NCI)Hs.591997
Alternative Splicing GalleryENSG00000188487
Gene ExpressionINSC [ NCBI-GEO ]   INSC [ EBI - ARRAY_EXPRESS ]   INSC [ SEEK ]   INSC [ MEM ]
Gene Expression Viewer (FireBrowse)INSC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)387755
GTEX Portal (Tissue expression)INSC
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ1MX18   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ1MX18  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ1MX18
Splice isoforms : SwissVarQ1MX18
PhosPhoSitePlusQ1MX18
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Armadillo    INSC_LBD   
Domain families : Pfam (Sanger)INSC_LBD (PF16748)   
Domain families : Pfam (NCBI)pfam16748   
Domain families : Smart (EMBL)ARM (SM00185)  
Conserved Domain (NCBI)INSC
DMDM Disease mutations387755
Blocks (Seattle)INSC
PDB (SRS)3SF4   
PDB (PDBSum)3SF4   
PDB (IMB)3SF4   
PDB (RSDB)3SF4   
Structural Biology KnowledgeBase3SF4   
SCOP (Structural Classification of Proteins)3SF4   
CATH (Classification of proteins structures)3SF4   
SuperfamilyQ1MX18
Human Protein AtlasENSG00000188487
Peptide AtlasQ1MX18
IPIIPI00398916   IPI00791267   IPI00641941   IPI00642408   IPI00783976   IPI00953239   IPI00815736   IPI00816575   
Protein Interaction databases
DIP (DOE-UCLA)Q1MX18
IntAct (EBI)Q1MX18
FunCoupENSG00000188487
BioGRIDINSC
STRING (EMBL)INSC
ZODIACINSC
Ontologies - Pathways
QuickGOQ1MX18
Ontology : AmiGOcell cortex  nervous system development  cell differentiation  
Ontology : EGO-EBIcell cortex  nervous system development  cell differentiation  
NDEx NetworkINSC
Atlas of Cancer Signalling NetworkINSC
Wikipedia pathwaysINSC
Orthology - Evolution
OrthoDB387755
GeneTree (enSembl)ENSG00000188487
Phylogenetic Trees/Animal Genes : TreeFamINSC
HOVERGENQ1MX18
HOGENOMQ1MX18
Homologs : HomoloGeneINSC
Homology/Alignments : Family Browser (UCSC)INSC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSC
dbVarINSC
ClinVarINSC
1000_GenomesINSC 
Exome Variant ServerINSC
ExAC (Exome Aggregation Consortium)INSC (select the gene name)
Genetic variants : HAPMAP387755
Genomic Variants (DGV)INSC [DGVbeta]
DECIPHERINSC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINSC 
Mutations
ICGC Data PortalINSC 
TCGA Data PortalINSC 
Broad Tumor PortalINSC
OASIS PortalINSC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINSC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINSC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INSC
DgiDB (Drug Gene Interaction Database)INSC
DoCM (Curated mutations)INSC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INSC (select a term)
intoGenINSC
Cancer3DINSC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610668   
Orphanet
MedgenINSC
Genetic Testing Registry INSC
NextProtQ1MX18 [Medical]
TSGene387755
GENETestsINSC
Target ValidationINSC
Huge Navigator INSC [HugePedia]
snp3D : Map Gene to Disease387755
BioCentury BCIQINSC
ClinGenINSC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD387755
Chemical/Pharm GKB GenePA162392191
Clinical trialINSC
Miscellaneous
canSAR (ICR)INSC (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINSC
EVEXINSC
GoPubMedINSC
iHOPINSC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:53:31 CEST 2017

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