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INSL6 (insulin like 6)

Identity

Alias_namesinsulin-like 6
Alias_symbol (synonym)RIF1
Other alias
HGNC (Hugo) INSL6
LocusID (NCBI) 11172
Atlas_Id 64624
Location 9p24.1  [Link to chromosome band 9p24]
Location_base_pair Starts at 5163863 and ends at 5185618 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INSL6   6089
Cards
Entrez_Gene (NCBI)INSL6  11172  insulin like 6
AliasesRIF1
GeneCards (Weizmann)INSL6
Ensembl hg19 (Hinxton)ENSG00000120210 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120210 [Gene_View]  chr9:5163863-5185618 [Contig_View]  INSL6 [Vega]
ICGC DataPortalENSG00000120210
TCGA cBioPortalINSL6
AceView (NCBI)INSL6
Genatlas (Paris)INSL6
WikiGenes11172
SOURCE (Princeton)INSL6
Genetics Home Reference (NIH)INSL6
Genomic and cartography
GoldenPath hg38 (UCSC)INSL6  -     chr9:5163863-5185618 -  9p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INSL6  -     9p24.1   [Description]    (hg19-Feb_2009)
EnsemblINSL6 - 9p24.1 [CytoView hg19]  INSL6 - 9p24.1 [CytoView hg38]
Mapping of homologs : NCBIINSL6 [Mapview hg19]  INSL6 [Mapview hg38]
OMIM606414   
Gene and transcription
Genbank (Entrez)AF135824 AF156094 AW117587 BC126473 BC126475
RefSeq transcript (Entrez)NM_007179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INSL6
Cluster EST : UnigeneHs.632648 [ NCBI ]
CGAP (NCI)Hs.632648
Alternative Splicing GalleryENSG00000120210
Gene ExpressionINSL6 [ NCBI-GEO ]   INSL6 [ EBI - ARRAY_EXPRESS ]   INSL6 [ SEEK ]   INSL6 [ MEM ]
Gene Expression Viewer (FireBrowse)INSL6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11172
GTEX Portal (Tissue expression)INSL6
Human Protein AtlasENSG00000120210-INSL6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y581   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y581  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y581
Splice isoforms : SwissVarQ9Y581
PhosPhoSitePlusQ9Y581
Domaine pattern : Prosite (Expaxy)INSULIN (PS00262)   
Domains : Interpro (EBI)Insulin-like    Insulin-like_pep_6    Insulin_CS   
Domain families : Pfam (Sanger)Insulin (PF00049)   
Domain families : Pfam (NCBI)pfam00049   
Domain families : Smart (EMBL)IlGF (SM00078)  
Conserved Domain (NCBI)INSL6
DMDM Disease mutations11172
Blocks (Seattle)INSL6
SuperfamilyQ9Y581
Human Protein Atlas [tissue]ENSG00000120210-INSL6 [tissue]
Peptide AtlasQ9Y581
HPRD08401
IPIIPI00294949   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y581
IntAct (EBI)Q9Y581
FunCoupENSG00000120210
BioGRIDINSL6
STRING (EMBL)INSL6
ZODIACINSL6
Ontologies - Pathways
QuickGOQ9Y581
Ontology : AmiGOhormone activity  cellular_component  extracellular region  spermatid development  biological_process  male gonad development  fertilization  flagellated sperm motility  negative regulation of apoptotic process  
Ontology : EGO-EBIhormone activity  cellular_component  extracellular region  spermatid development  biological_process  male gonad development  fertilization  flagellated sperm motility  negative regulation of apoptotic process  
NDEx NetworkINSL6
Atlas of Cancer Signalling NetworkINSL6
Wikipedia pathwaysINSL6
Orthology - Evolution
OrthoDB11172
GeneTree (enSembl)ENSG00000120210
Phylogenetic Trees/Animal Genes : TreeFamINSL6
HOVERGENQ9Y581
HOGENOMQ9Y581
Homologs : HomoloGeneINSL6
Homology/Alignments : Family Browser (UCSC)INSL6
Gene fusions - Rearrangements
Tumor Fusion PortalINSL6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSL6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSL6
dbVarINSL6
ClinVarINSL6
1000_GenomesINSL6 
Exome Variant ServerINSL6
ExAC (Exome Aggregation Consortium)ENSG00000120210
GNOMAD BrowserENSG00000120210
Genetic variants : HAPMAP11172
Genomic Variants (DGV)INSL6 [DGVbeta]
DECIPHERINSL6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINSL6 
Mutations
ICGC Data PortalINSL6 
TCGA Data PortalINSL6 
Broad Tumor PortalINSL6
OASIS PortalINSL6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINSL6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINSL6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INSL6
DgiDB (Drug Gene Interaction Database)INSL6
DoCM (Curated mutations)INSL6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INSL6 (select a term)
intoGenINSL6
Cancer3DINSL6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606414   
Orphanet
DisGeNETINSL6
MedgenINSL6
Genetic Testing Registry INSL6
NextProtQ9Y581 [Medical]
TSGene11172
GENETestsINSL6
Target ValidationINSL6
Huge Navigator INSL6 [HugePedia]
snp3D : Map Gene to Disease11172
BioCentury BCIQINSL6
ClinGenINSL6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11172
Chemical/Pharm GKB GenePA29896
Clinical trialINSL6
Miscellaneous
canSAR (ICR)INSL6 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINSL6
EVEXINSL6
GoPubMedINSL6
iHOPINSL6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:19:54 CET 2017

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