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INSM1 (insulinoma associated 1)

Identity

Alias_namesinsulinoma-associated 1
insulinoma associated 1
Alias_symbol (synonym)IA-1
IA1
Other alias
HGNC (Hugo) INSM1
LocusID (NCBI) 3642
Atlas_Id 40985
Location 20p11.23  [Link to chromosome band 20p11]
Location_base_pair Starts at 20348765 and ends at 20351592 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INSM1   6090
Cards
Entrez_Gene (NCBI)INSM1  3642  insulinoma associated 1
AliasesIA-1; IA1
GeneCards (Weizmann)INSM1
Ensembl hg19 (Hinxton)ENSG00000173404 [Gene_View]  chr20:20348765-20351592 [Contig_View]  INSM1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173404 [Gene_View]  chr20:20348765-20351592 [Contig_View]  INSM1 [Vega]
ICGC DataPortalENSG00000173404
TCGA cBioPortalINSM1
AceView (NCBI)INSM1
Genatlas (Paris)INSM1
WikiGenes3642
SOURCE (Princeton)INSM1
Genetics Home Reference (NIH)INSM1
Genomic and cartography
GoldenPath hg19 (UCSC)INSM1  -     chr20:20348765-20351592 +  20p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)INSM1  -     20p11.23   [Description]    (hg38-Dec_2013)
EnsemblINSM1 - 20p11.23 [CytoView hg19]  INSM1 - 20p11.23 [CytoView hg38]
Mapping of homologs : NCBIINSM1 [Mapview hg19]  INSM1 [Mapview hg38]
OMIM600010   
Gene and transcription
Genbank (Entrez)BM503821 M93119
RefSeq transcript (Entrez)NM_002196
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)INSM1
Cluster EST : UnigeneHs.89584 [ NCBI ]
CGAP (NCI)Hs.89584
Alternative Splicing GalleryENSG00000173404
Gene ExpressionINSM1 [ NCBI-GEO ]   INSM1 [ EBI - ARRAY_EXPRESS ]   INSM1 [ SEEK ]   INSM1 [ MEM ]
Gene Expression Viewer (FireBrowse)INSM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3642
GTEX Portal (Tissue expression)INSM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01101   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01101  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01101
Splice isoforms : SwissVarQ01101
PhosPhoSitePlusQ01101
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)INSM1
DMDM Disease mutations3642
Blocks (Seattle)INSM1
PDB (SRS)2LV2    3ZMS   
PDB (PDBSum)2LV2    3ZMS   
PDB (IMB)2LV2    3ZMS   
PDB (RSDB)2LV2    3ZMS   
Structural Biology KnowledgeBase2LV2    3ZMS   
SCOP (Structural Classification of Proteins)2LV2    3ZMS   
CATH (Classification of proteins structures)2LV2    3ZMS   
SuperfamilyQ01101
Human Protein AtlasENSG00000173404
Peptide AtlasQ01101
HPRD02480
IPIIPI00005944   
Protein Interaction databases
DIP (DOE-UCLA)Q01101
IntAct (EBI)Q01101
FunCoupENSG00000173404
BioGRIDINSM1
STRING (EMBL)INSM1
ZODIACINSM1
Ontologies - Pathways
QuickGOQ01101
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  negative regulation of protein phosphorylation  type B pancreatic cell differentiation  pancreatic A cell differentiation  type B pancreatic cell development  noradrenergic neuron development  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  transcription, DNA-templated  cell cycle  negative regulation of cell proliferation  regulation of gene expression  transcriptional repressor complex  cyclin binding  positive regulation of cell migration  endocrine pancreas development  chromatin DNA binding  norepinephrine biosynthetic process  histone deacetylase binding  regulation of protein complex assembly  positive regulation of cell differentiation  metal ion binding  transdifferentiation  adrenal chromaffin cell differentiation  sympathetic ganglion development  positive regulation of cell cycle arrest  positive regulation of neural precursor cell proliferation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  negative regulation of protein phosphorylation  type B pancreatic cell differentiation  pancreatic A cell differentiation  type B pancreatic cell development  noradrenergic neuron development  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  transcription, DNA-templated  cell cycle  negative regulation of cell proliferation  regulation of gene expression  transcriptional repressor complex  cyclin binding  positive regulation of cell migration  endocrine pancreas development  chromatin DNA binding  norepinephrine biosynthetic process  histone deacetylase binding  regulation of protein complex assembly  positive regulation of cell differentiation  metal ion binding  transdifferentiation  adrenal chromaffin cell differentiation  sympathetic ganglion development  positive regulation of cell cycle arrest  positive regulation of neural precursor cell proliferation  
NDEx NetworkINSM1
Atlas of Cancer Signalling NetworkINSM1
Wikipedia pathwaysINSM1
Orthology - Evolution
OrthoDB3642
GeneTree (enSembl)ENSG00000173404
Phylogenetic Trees/Animal Genes : TreeFamINSM1
HOVERGENQ01101
HOGENOMQ01101
Homologs : HomoloGeneINSM1
Homology/Alignments : Family Browser (UCSC)INSM1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSM1
dbVarINSM1
ClinVarINSM1
1000_GenomesINSM1 
Exome Variant ServerINSM1
ExAC (Exome Aggregation Consortium)INSM1 (select the gene name)
Genetic variants : HAPMAP3642
Genomic Variants (DGV)INSM1 [DGVbeta]
DECIPHER (Syndromes)20:20348765-20351592  ENSG00000173404
CONAN: Copy Number AnalysisINSM1 
Mutations
ICGC Data PortalINSM1 
TCGA Data PortalINSM1 
Broad Tumor PortalINSM1
OASIS PortalINSM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINSM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINSM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INSM1
DgiDB (Drug Gene Interaction Database)INSM1
DoCM (Curated mutations)INSM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INSM1 (select a term)
intoGenINSM1
Cancer3DINSM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600010   
Orphanet
MedgenINSM1
Genetic Testing Registry INSM1
NextProtQ01101 [Medical]
TSGene3642
GENETestsINSM1
Huge Navigator INSM1 [HugePedia]
snp3D : Map Gene to Disease3642
BioCentury BCIQINSM1
ClinGenINSM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3642
Chemical/Pharm GKB GenePA29897
Clinical trialINSM1
Miscellaneous
canSAR (ICR)INSM1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINSM1
EVEXINSM1
GoPubMedINSM1
iHOPINSM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:10:56 CET 2017

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