INSM1 (INSM transcriptional repressor 1)

2003-02-01  

Identity

HGNC
LOCATION
20p11.23
LOCUSID
ALIAS
IA-1,IA1

Other Information

Locus ID:

NCBI: 3642
MIM: 600010
HGNC: 6090
Ensembl: ENSG00000173404

Variants:

dbSNP: 3642
ClinVar: 3642
TCGA: ENSG00000173404
COSMIC: INSM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173404ENST00000310227Q01101

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Regulation of beta-cell developmentREACTOMER-HSA-186712
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cellsREACTOMER-HSA-210746

References

Pubmed IDYearTitleCitations
381710812024INSM1 expression in primary and metastatic neuroendocrine neoplasms at distinct locations.1
381710812024INSM1 expression in primary and metastatic neuroendocrine neoplasms at distinct locations.1
362452222023Immunosensitivity and specificity of insulinoma-associated protein 1 (INSM1) for neuroendocrine neoplasms of the uterine cervix.3
365638842023Extraskeletal myxoid chondrosarcoma: A study of 17 cases focusing on the diagnostic utility of INSM1 expression and presenting rare morphological variants associated with non-EWSR1::NR4A3 fusions.1
362452222023Immunosensitivity and specificity of insulinoma-associated protein 1 (INSM1) for neuroendocrine neoplasms of the uterine cervix.3
365638842023Extraskeletal myxoid chondrosarcoma: A study of 17 cases focusing on the diagnostic utility of INSM1 expression and presenting rare morphological variants associated with non-EWSR1::NR4A3 fusions.1
335156272022Next-generation sequencing analysis suggests varied multistep mutational pathogenesis for endocrine mucin-producing sweat gland carcinoma with comments on INSM1 and MUC2 suggesting a conjunctival origin.3
340866462022Utility of Insulinoma-Associated Protein 1 (INSM1) and Mucin 2 (MUC2) Immunohistochemistry in the Distinction of Endocrine Mucin-Producing Sweat Gland Carcinoma From Morphologic Mimics.3
351473012022Exploration of INSM1 and hASH1 as additional markers in lung cytology samples of high-grade neuroendocrine carcinoma with indeterminate neuroendocrine differentiation.2
363059442022Insulinoma-associated-1 (INSM1) expression in thymic squamous cell carcinoma.3
365316552022INSM1 Expression in Mesenchymal Tumors and Its Clinicopathological Significance.1
335156272022Next-generation sequencing analysis suggests varied multistep mutational pathogenesis for endocrine mucin-producing sweat gland carcinoma with comments on INSM1 and MUC2 suggesting a conjunctival origin.3
340866462022Utility of Insulinoma-Associated Protein 1 (INSM1) and Mucin 2 (MUC2) Immunohistochemistry in the Distinction of Endocrine Mucin-Producing Sweat Gland Carcinoma From Morphologic Mimics.3
351473012022Exploration of INSM1 and hASH1 as additional markers in lung cytology samples of high-grade neuroendocrine carcinoma with indeterminate neuroendocrine differentiation.2
363059442022Insulinoma-associated-1 (INSM1) expression in thymic squamous cell carcinoma.3

Citation

Dessen P

INSM1 (INSM transcriptional repressor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40985/insm1