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INSM2 (INSM transcriptional repressor 2)

Identity

Alias_namesinsulinoma-associated 2
Alias_symbol (synonym)IA-6
Mlt1
Other aliasIA6
mlt1
HGNC (Hugo) INSM2
LocusID (NCBI) 84684
Atlas_Id 64625
Location 14q13.2  [Link to chromosome band 14q13]
Location_base_pair Starts at 35534042 and ends at 35537054 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INSM2   17539
Cards
Entrez_Gene (NCBI)INSM2  84684  INSM transcriptional repressor 2
AliasesIA-6; IA6; mlt1
GeneCards (Weizmann)INSM2
Ensembl hg19 (Hinxton)ENSG00000168348 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168348 [Gene_View]  chr14:35534042-35537054 [Contig_View]  INSM2 [Vega]
ICGC DataPortalENSG00000168348
TCGA cBioPortalINSM2
AceView (NCBI)INSM2
Genatlas (Paris)INSM2
WikiGenes84684
SOURCE (Princeton)INSM2
Genetics Home Reference (NIH)INSM2
Genomic and cartography
GoldenPath hg38 (UCSC)INSM2  -     chr14:35534042-35537054 +  14q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INSM2  -     14q13.2   [Description]    (hg19-Feb_2009)
EnsemblINSM2 - 14q13.2 [CytoView hg19]  INSM2 - 14q13.2 [CytoView hg38]
Mapping of homologs : NCBIINSM2 [Mapview hg19]  INSM2 [Mapview hg38]
OMIM614027   
Gene and transcription
Genbank (Entrez)AB037912 AF260323 AK096639 BC130377 BC130379
RefSeq transcript (Entrez)NM_032594
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INSM2
Cluster EST : UnigeneHs.62813 [ NCBI ]
CGAP (NCI)Hs.62813
Alternative Splicing GalleryENSG00000168348
Gene ExpressionINSM2 [ NCBI-GEO ]   INSM2 [ EBI - ARRAY_EXPRESS ]   INSM2 [ SEEK ]   INSM2 [ MEM ]
Gene Expression Viewer (FireBrowse)INSM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84684
GTEX Portal (Tissue expression)INSM2
Human Protein AtlasENSG00000168348-INSM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96T92   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96T92  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96T92
Splice isoforms : SwissVarQ96T92
PhosPhoSitePlusQ96T92
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)INSM2
DMDM Disease mutations84684
Blocks (Seattle)INSM2
SuperfamilyQ96T92
Human Protein Atlas [tissue]ENSG00000168348-INSM2 [tissue]
Peptide AtlasQ96T92
HPRD17152
IPIIPI00045936   
Protein Interaction databases
DIP (DOE-UCLA)Q96T92
IntAct (EBI)Q96T92
FunCoupENSG00000168348
BioGRIDINSM2
STRING (EMBL)INSM2
ZODIACINSM2
Ontologies - Pathways
QuickGOQ96T92
Ontology : AmiGODNA binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkINSM2
Atlas of Cancer Signalling NetworkINSM2
Wikipedia pathwaysINSM2
Orthology - Evolution
OrthoDB84684
GeneTree (enSembl)ENSG00000168348
Phylogenetic Trees/Animal Genes : TreeFamINSM2
HOVERGENQ96T92
HOGENOMQ96T92
Homologs : HomoloGeneINSM2
Homology/Alignments : Family Browser (UCSC)INSM2
Gene fusions - Rearrangements
Fusion: Tumor Portal INSM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSM2
dbVarINSM2
ClinVarINSM2
1000_GenomesINSM2 
Exome Variant ServerINSM2
ExAC (Exome Aggregation Consortium)ENSG00000168348
GNOMAD BrowserENSG00000168348
Genetic variants : HAPMAP84684
Genomic Variants (DGV)INSM2 [DGVbeta]
DECIPHERINSM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINSM2 
Mutations
ICGC Data PortalINSM2 
TCGA Data PortalINSM2 
Broad Tumor PortalINSM2
OASIS PortalINSM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINSM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINSM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INSM2
DgiDB (Drug Gene Interaction Database)INSM2
DoCM (Curated mutations)INSM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INSM2 (select a term)
intoGenINSM2
Cancer3DINSM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614027   
Orphanet
MedgenINSM2
Genetic Testing Registry INSM2
NextProtQ96T92 [Medical]
TSGene84684
GENETestsINSM2
Target ValidationINSM2
Huge Navigator INSM2 [HugePedia]
snp3D : Map Gene to Disease84684
BioCentury BCIQINSM2
ClinGenINSM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84684
Chemical/Pharm GKB GenePA134899231
Clinical trialINSM2
Miscellaneous
canSAR (ICR)INSM2 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINSM2
EVEXINSM2
GoPubMedINSM2
iHOPINSM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:51:35 CET 2017

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