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INSYN1 (inhibitory synaptic factor 1)

Identity

Alias (NCBI)C15orf59
HGNC (Hugo) INSYN1
LocusID (NCBI) 388135
Atlas_Id 80535
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 73735431 and ends at 73752370 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)INSYN1   33753
Cards
Entrez_Gene (NCBI)INSYN1  388135  inhibitory synaptic factor 1
AliasesC15orf59
GeneCards (Weizmann)INSYN1
Ensembl hg19 (Hinxton)ENSG00000205363 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205363 [Gene_View]  ENSG00000205363 [Sequence]  chr15:73735431-73752370 [Contig_View]  INSYN1 [Vega]
ICGC DataPortalENSG00000205363
TCGA cBioPortalINSYN1
AceView (NCBI)INSYN1
Genatlas (Paris)INSYN1
WikiGenes388135
SOURCE (Princeton)INSYN1
Genetics Home Reference (NIH)INSYN1
Genomic and cartography
GoldenPath hg38 (UCSC)INSYN1  -     chr15:73735431-73752370 -  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INSYN1  -     15q24.1   [Description]    (hg19-Feb_2009)
GoldenPathINSYN1 - 15q24.1 [CytoView hg19]  INSYN1 - 15q24.1 [CytoView hg38]
ImmunoBaseENSG00000205363
genome Data Viewer NCBIINSYN1 [Mapview hg19]  
OMIM617128   
Gene and transcription
Genbank (Entrez)AK124841 AL360257 BC111368 CK823338 DR003635
RefSeq transcript (Entrez)NM_001039614 NM_001303254
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INSYN1
Alternative Splicing GalleryENSG00000205363
Gene ExpressionINSYN1 [ NCBI-GEO ]   INSYN1 [ EBI - ARRAY_EXPRESS ]   INSYN1 [ SEEK ]   INSYN1 [ MEM ]
Gene Expression Viewer (FireBrowse)INSYN1 [ Firebrowse - Broad ]
GenevisibleExpression of INSYN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)388135
GTEX Portal (Tissue expression)INSYN1
Human Protein AtlasENSG00000205363-INSYN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2T9L4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2T9L4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2T9L4
Splice isoforms : SwissVarQ2T9L4
PhosPhoSitePlusQ2T9L4
Domains : Interpro (EBI)Largen/INSYN1   
Domain families : Pfam (Sanger)DUF4589 (PF15252)   
Domain families : Pfam (NCBI)pfam15252   
Conserved Domain (NCBI)INSYN1
DMDM Disease mutations388135
Blocks (Seattle)INSYN1
SuperfamilyQ2T9L4
Human Protein Atlas [tissue]ENSG00000205363-INSYN1 [tissue]
Peptide AtlasQ2T9L4
IPIIPI00376058   
Protein Interaction databases
DIP (DOE-UCLA)Q2T9L4
IntAct (EBI)Q2T9L4
FunCoupENSG00000205363
BioGRIDINSYN1
STRING (EMBL)INSYN1
ZODIACINSYN1
Ontologies - Pathways
QuickGOQ2T9L4
Ontology : AmiGOpostsynaptic density  cell junction  postsynaptic membrane  inhibitory postsynaptic potential  
Ontology : EGO-EBIpostsynaptic density  cell junction  postsynaptic membrane  inhibitory postsynaptic potential  
NDEx NetworkINSYN1
Atlas of Cancer Signalling NetworkINSYN1
Wikipedia pathwaysINSYN1
Orthology - Evolution
OrthoDB388135
GeneTree (enSembl)ENSG00000205363
Phylogenetic Trees/Animal Genes : TreeFamINSYN1
HOGENOMQ2T9L4
Homologs : HomoloGeneINSYN1
Homology/Alignments : Family Browser (UCSC)INSYN1
Gene fusions - Rearrangements
Fusion : QuiverINSYN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSYN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSYN1
dbVarINSYN1
ClinVarINSYN1
1000_GenomesINSYN1 
Exome Variant ServerINSYN1
GNOMAD BrowserENSG00000205363
Varsome BrowserINSYN1
Genetic variants : HAPMAP388135
Genomic Variants (DGV)INSYN1 [DGVbeta]
DECIPHERINSYN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINSYN1 
Mutations
ICGC Data PortalINSYN1 
TCGA Data PortalINSYN1 
Broad Tumor PortalINSYN1
OASIS PortalINSYN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINSYN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DINSYN1
Mutations and Diseases : HGMDINSYN1
BioMutasearch INSYN1
DgiDB (Drug Gene Interaction Database)INSYN1
DoCM (Curated mutations)INSYN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INSYN1 (select a term)
intoGenINSYN1
Cancer3DINSYN1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617128   
Orphanet
DisGeNETINSYN1
MedgenINSYN1
Genetic Testing Registry INSYN1
NextProtQ2T9L4 [Medical]
TSGene388135
GENETestsINSYN1
Target ValidationINSYN1
Huge Navigator INSYN1 [HugePedia]
snp3D : Map Gene to Disease388135
BioCentury BCIQINSYN1
ClinGenINSYN1
Clinical trials, drugs, therapy
Protein Interactions : CTD388135
Pharm GKB GenePA162378260
Clinical trialINSYN1
Miscellaneous
canSAR (ICR)INSYN1 (select the gene name)
HarmonizomeINSYN1
DataMed IndexINSYN1
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINSYN1
EVEXINSYN1
GoPubMedINSYN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:59:10 CEST 2020

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