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INSYN2A (inhibitory synaptic factor 2A)

Identity

Alias (NCBI)C10orf141
FAM196A
INSYN2
HGNC (Hugo) INSYN2A
HGNC Alias symbFLJ45557
HGNC Previous nameC10orf141
HGNC Previous namechromosome 10 open reading frame 141
 family with sequence similarity 196, member A
LocusID (NCBI) 642938
Atlas_Id 63106
Location 10q26.2  [Link to chromosome band 10q26]
Location_base_pair Starts at 127135430 and ends at 127196591 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)INSYN2A   33859
Cards
Entrez_Gene (NCBI)INSYN2A    inhibitory synaptic factor 2A
AliasesC10orf141; FAM196A; INSYN2
GeneCards (Weizmann)INSYN2A
Ensembl hg19 (Hinxton)ENSG00000188916 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188916 [Gene_View]  ENSG00000188916 [Sequence]  chr10:127135430-127196591 [Contig_View]  INSYN2A [Vega]
ICGC DataPortalENSG00000188916
TCGA cBioPortalINSYN2A
AceView (NCBI)INSYN2A
Genatlas (Paris)INSYN2A
SOURCE (Princeton)INSYN2A
Genetics Home Reference (NIH)INSYN2A
Genomic and cartography
GoldenPath hg38 (UCSC)INSYN2A  -     chr10:127135430-127196591 -  10q26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INSYN2A  -     10q26.2   [Description]    (hg19-Feb_2009)
GoldenPathINSYN2A - 10q26.2 [CytoView hg19]  INSYN2A - 10q26.2 [CytoView hg38]
ImmunoBaseENSG00000188916
Genome Data Viewer NCBIINSYN2A [Mapview hg19]  
OMIM617129   
Gene and transcription
Genbank (Entrez)AK127465 BC131825 BC137112 BC144478
RefSeq transcript (Entrez)NM_001039762
Consensus coding sequences : CCDS (NCBI)INSYN2A
Gene ExpressionINSYN2A [ NCBI-GEO ]   INSYN2A [ EBI - ARRAY_EXPRESS ]   INSYN2A [ SEEK ]   INSYN2A [ MEM ]
Gene Expression Viewer (FireBrowse)INSYN2A [ Firebrowse - Broad ]
GenevisibleExpression of INSYN2A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)642938
GTEX Portal (Tissue expression)INSYN2A
Human Protein AtlasENSG00000188916-INSYN2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZSG2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZSG2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZSG2
PhosPhoSitePlusQ6ZSG2
Domains : Interpro (EBI)INSYN2   
Domain families : Pfam (Sanger)FAM196 (PF15265)   
Domain families : Pfam (NCBI)pfam15265   
Conserved Domain (NCBI)INSYN2A
SuperfamilyQ6ZSG2
AlphaFold pdb e-kbQ6ZSG2   
Human Protein Atlas [tissue]ENSG00000188916-INSYN2A [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q6ZSG2
IntAct (EBI)Q6ZSG2
BioGRIDINSYN2A
STRING (EMBL)INSYN2A
ZODIACINSYN2A
Ontologies - Pathways
QuickGOQ6ZSG2
Ontology : AmiGOprotein binding  postsynaptic density  postsynaptic density  inhibitory postsynaptic potential  inhibitory postsynaptic potential  
Ontology : EGO-EBIprotein binding  postsynaptic density  postsynaptic density  inhibitory postsynaptic potential  inhibitory postsynaptic potential  
NDEx NetworkINSYN2A
Atlas of Cancer Signalling NetworkINSYN2A
Wikipedia pathwaysINSYN2A
Orthology - Evolution
OrthoDB642938
GeneTree (enSembl)ENSG00000188916
Phylogenetic Trees/Animal Genes : TreeFamINSYN2A
Homologs : HomoloGeneINSYN2A
Homology/Alignments : Family Browser (UCSC)INSYN2A
Gene fusions - Rearrangements
Fusion : QuiverINSYN2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINSYN2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INSYN2A
dbVarINSYN2A
ClinVarINSYN2A
MonarchINSYN2A
1000_GenomesINSYN2A 
Exome Variant ServerINSYN2A
GNOMAD BrowserENSG00000188916
Varsome BrowserINSYN2A
ACMGINSYN2A variants
VarityQ6ZSG2
Genomic Variants (DGV)INSYN2A [DGVbeta]
DECIPHERINSYN2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINSYN2A 
Mutations
ICGC Data PortalINSYN2A 
TCGA Data PortalINSYN2A 
Broad Tumor PortalINSYN2A
OASIS PortalINSYN2A [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDINSYN2A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaINSYN2A
DgiDB (Drug Gene Interaction Database)INSYN2A
DoCM (Curated mutations)INSYN2A
CIViC (Clinical Interpretations of Variants in Cancer)INSYN2A
Cancer3DINSYN2A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617129   
Orphanet
DisGeNETINSYN2A
MedgenINSYN2A
Genetic Testing Registry INSYN2A
NextProtQ6ZSG2 [Medical]
GENETestsINSYN2A
Target ValidationINSYN2A
Huge Navigator INSYN2A [HugePedia]
ClinGenINSYN2A
Clinical trials, drugs, therapy
MyCancerGenomeINSYN2A
Protein Interactions : CTDINSYN2A
Pharm GKB GenePA165548646
PharosQ6ZSG2
Clinical trialINSYN2A
Miscellaneous
canSAR (ICR)INSYN2A
HarmonizomeINSYN2A
DataMed IndexINSYN2A
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXINSYN2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:53:49 CEST 2021

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