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INTS1 (integrator complex subunit 1)

Identity

Alias_symbol (synonym)DKFZp586J0619
KIAA1440
INT1
NET28
Other alias
HGNC (Hugo) INTS1
LocusID (NCBI) 26173
Atlas_Id 54380
Location 7p22.3  [Link to chromosome band 7p22]
Location_base_pair Starts at 1470277 and ends at 1504382 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARPC4-TTLL3 (3p25.3) / INTS1 (7p22.3)INTS1 (7p22.3) / INTS1 (7p22.3)INTS1 (7p22.3) / PRKAR1B (7p22.3)
INTS1 (7p22.3) / SQSTM1 (5q35.3)INTS1 (7p22.3) / TBRG4 (7p13)INTS1 (7p22.3) / TMC4 (19q13.42)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTS1   24555
Cards
Entrez_Gene (NCBI)INTS1  26173  integrator complex subunit 1
AliasesINT1; NET28
GeneCards (Weizmann)INTS1
Ensembl hg19 (Hinxton)ENSG00000164880 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164880 [Gene_View]  chr7:1470277-1504382 [Contig_View]  INTS1 [Vega]
ICGC DataPortalENSG00000164880
TCGA cBioPortalINTS1
AceView (NCBI)INTS1
Genatlas (Paris)INTS1
WikiGenes26173
SOURCE (Princeton)INTS1
Genetics Home Reference (NIH)INTS1
Genomic and cartography
GoldenPath hg38 (UCSC)INTS1  -     chr7:1470277-1504382 -  7p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTS1  -     7p22.3   [Description]    (hg19-Feb_2009)
EnsemblINTS1 - 7p22.3 [CytoView hg19]  INTS1 - 7p22.3 [CytoView hg38]
Mapping of homologs : NCBIINTS1 [Mapview hg19]  INTS1 [Mapview hg38]
OMIM611345   
Gene and transcription
Genbank (Entrez)AB037861 AI935093 AK128368 AL050110 AL137358
RefSeq transcript (Entrez)NM_001080453
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INTS1
Cluster EST : UnigeneHs.532188 [ NCBI ]
CGAP (NCI)Hs.532188
Alternative Splicing GalleryENSG00000164880
Gene ExpressionINTS1 [ NCBI-GEO ]   INTS1 [ EBI - ARRAY_EXPRESS ]   INTS1 [ SEEK ]   INTS1 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26173
GTEX Portal (Tissue expression)INTS1
Human Protein AtlasENSG00000164880-INTS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N201   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N201  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N201
Splice isoforms : SwissVarQ8N201
PhosPhoSitePlusQ8N201
Domains : Interpro (EBI)ARM-type_fold    DUF3677   
Domain families : Pfam (Sanger)DUF3677 (PF12432)   
Domain families : Pfam (NCBI)pfam12432   
Conserved Domain (NCBI)INTS1
DMDM Disease mutations26173
Blocks (Seattle)INTS1
SuperfamilyQ8N201
Human Protein Atlas [tissue]ENSG00000164880-INTS1 [tissue]
Peptide AtlasQ8N201
IPIIPI00876931   IPI00740961   IPI00946694   
Protein Interaction databases
DIP (DOE-UCLA)Q8N201
IntAct (EBI)Q8N201
FunCoupENSG00000164880
BioGRIDINTS1
STRING (EMBL)INTS1
ZODIACINTS1
Ontologies - Pathways
QuickGOQ8N201
Ontology : AmiGOnucleoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  U2 snRNA 3'-end processing  snRNA transcription from RNA polymerase II promoter  
Ontology : EGO-EBInucleoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  U2 snRNA 3'-end processing  snRNA transcription from RNA polymerase II promoter  
NDEx NetworkINTS1
Atlas of Cancer Signalling NetworkINTS1
Wikipedia pathwaysINTS1
Orthology - Evolution
OrthoDB26173
GeneTree (enSembl)ENSG00000164880
Phylogenetic Trees/Animal Genes : TreeFamINTS1
HOVERGENQ8N201
HOGENOMQ8N201
Homologs : HomoloGeneINTS1
Homology/Alignments : Family Browser (UCSC)INTS1
Gene fusions - Rearrangements
Fusion : MitelmanINTS1/PRKAR1B [7p22.3/7p22.3]  
Tumor Fusion PortalINTS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS1
dbVarINTS1
ClinVarINTS1
1000_GenomesINTS1 
Exome Variant ServerINTS1
ExAC (Exome Aggregation Consortium)ENSG00000164880
GNOMAD BrowserENSG00000164880
Genetic variants : HAPMAP26173
Genomic Variants (DGV)INTS1 [DGVbeta]
DECIPHERINTS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTS1 
Mutations
ICGC Data PortalINTS1 
TCGA Data PortalINTS1 
Broad Tumor PortalINTS1
OASIS PortalINTS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINTS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTS1
DgiDB (Drug Gene Interaction Database)INTS1
DoCM (Curated mutations)INTS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTS1 (select a term)
intoGenINTS1
Cancer3DINTS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611345   
Orphanet
DisGeNETINTS1
MedgenINTS1
Genetic Testing Registry INTS1
NextProtQ8N201 [Medical]
TSGene26173
GENETestsINTS1
Target ValidationINTS1
Huge Navigator INTS1 [HugePedia]
snp3D : Map Gene to Disease26173
BioCentury BCIQINTS1
ClinGenINTS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26173
Chemical/Pharm GKB GenePA144596420
Clinical trialINTS1
Miscellaneous
canSAR (ICR)INTS1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTS1
EVEXINTS1
GoPubMedINTS1
iHOPINTS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:58 CET 2017

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