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INTS11 (integrator complex subunit 11)

Identity

Alias_namesCPSF3L
cleavage and polyadenylation specific factor 3-like
Alias_symbol (synonym)FLJ20542
RC-68
CPSF73L
INT11
Other aliasRC68
HGNC (Hugo) INTS11
LocusID (NCBI) 54973
Atlas_Id 79300
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1311585 and ends at 1324687 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTS11   26052
Cards
Entrez_Gene (NCBI)INTS11  54973  integrator complex subunit 11
AliasesCPSF3L; CPSF73L; INT11; RC-68; 
RC68
GeneCards (Weizmann)INTS11
Ensembl hg19 (Hinxton)ENSG00000127054 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127054 [Gene_View]  chr1:1311585-1324687 [Contig_View]  INTS11 [Vega]
ICGC DataPortalENSG00000127054
TCGA cBioPortalINTS11
AceView (NCBI)INTS11
Genatlas (Paris)INTS11
WikiGenes54973
SOURCE (Princeton)INTS11
Genetics Home Reference (NIH)INTS11
Genomic and cartography
GoldenPath hg38 (UCSC)INTS11  -     chr1:1311585-1324687 -  1p36.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTS11  -     1p36.33   [Description]    (hg19-Feb_2009)
EnsemblINTS11 - 1p36.33 [CytoView hg19]  INTS11 - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBIINTS11 [Mapview hg19]  INTS11 [Mapview hg38]
OMIM611354   
Gene and transcription
Genbank (Entrez)AA687684 AK000549 AK021939 AK022675 AK023356
RefSeq transcript (Entrez)NM_001256456 NM_001256460 NM_001256462 NM_001256463 NM_017871 NM_032179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INTS11
Cluster EST : UnigeneHs.6449 [ NCBI ]
CGAP (NCI)Hs.6449
Alternative Splicing GalleryENSG00000127054
Gene ExpressionINTS11 [ NCBI-GEO ]   INTS11 [ EBI - ARRAY_EXPRESS ]   INTS11 [ SEEK ]   INTS11 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54973
GTEX Portal (Tissue expression)INTS11
Human Protein AtlasENSG00000127054-INTS11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TA45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TA45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TA45
Splice isoforms : SwissVarQ5TA45
Catalytic activity : Enzyme3.1.27.- [ Enzyme-Expasy ]   3.1.27.-3.1.27.- [ IntEnz-EBI ]   3.1.27.- [ BRENDA ]   3.1.27.- [ KEGG ]   
PhosPhoSitePlusQ5TA45
Domains : Interpro (EBI)Beta_Casp    Metallo-B-lactamas    RMMBL   
Domain families : Pfam (Sanger)Beta-Casp (PF10996)    Lactamase_B_6 (PF16661)    RMMBL (PF07521)   
Domain families : Pfam (NCBI)pfam10996    pfam16661    pfam07521   
Domain families : Smart (EMBL)Beta-Casp (SM01027)  Lactamase_B (SM00849)  
Conserved Domain (NCBI)INTS11
DMDM Disease mutations54973
Blocks (Seattle)INTS11
SuperfamilyQ5TA45
Human Protein Atlas [tissue]ENSG00000127054-INTS11 [tissue]
Peptide AtlasQ5TA45
IPIIPI00063404   IPI00306882   IPI00514973   IPI01011963   IPI00976242   IPI00514001   IPI00386782   IPI00513900   IPI00513774   IPI00514808   IPI00985429   IPI00983607   IPI00983072   IPI00982142   IPI00984775   IPI00983750   IPI00985405   IPI00979575   IPI00981641   IPI00977321   IPI00976734   IPI00982774   IPI00975582   
Protein Interaction databases
DIP (DOE-UCLA)Q5TA45
IntAct (EBI)Q5TA45
FunCoupENSG00000127054
BioGRIDINTS11
STRING (EMBL)INTS11
ZODIACINTS11
Ontologies - Pathways
QuickGOQ5TA45
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  snRNA processing  hydrolase activity  integrator complex  snRNA transcription from RNA polymerase II promoter  blood microparticle  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  snRNA processing  hydrolase activity  integrator complex  snRNA transcription from RNA polymerase II promoter  blood microparticle  
NDEx NetworkINTS11
Atlas of Cancer Signalling NetworkINTS11
Wikipedia pathwaysINTS11
Orthology - Evolution
OrthoDB54973
GeneTree (enSembl)ENSG00000127054
Phylogenetic Trees/Animal Genes : TreeFamINTS11
HOVERGENQ5TA45
HOGENOMQ5TA45
Homologs : HomoloGeneINTS11
Homology/Alignments : Family Browser (UCSC)INTS11
Gene fusions - Rearrangements
Tumor Fusion PortalINTS11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS11
dbVarINTS11
ClinVarINTS11
1000_GenomesINTS11 
Exome Variant ServerINTS11
ExAC (Exome Aggregation Consortium)ENSG00000127054
GNOMAD BrowserENSG00000127054
Genetic variants : HAPMAP54973
Genomic Variants (DGV)INTS11 [DGVbeta]
DECIPHERINTS11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTS11 
Mutations
ICGC Data PortalINTS11 
TCGA Data PortalINTS11 
Broad Tumor PortalINTS11
OASIS PortalINTS11 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDINTS11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTS11
DgiDB (Drug Gene Interaction Database)INTS11
DoCM (Curated mutations)INTS11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTS11 (select a term)
intoGenINTS11
Cancer3DINTS11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611354   
Orphanet
DisGeNETINTS11
MedgenINTS11
Genetic Testing Registry INTS11
NextProtQ5TA45 [Medical]
TSGene54973
GENETestsINTS11
Target ValidationINTS11
Huge Navigator INTS11 [HugePedia]
snp3D : Map Gene to Disease54973
BioCentury BCIQINTS11
ClinGenINTS11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54973
Chemical/Pharm GKB GenePA142672080
Clinical trialINTS11
Miscellaneous
canSAR (ICR)INTS11 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTS11
EVEXINTS11
GoPubMedINTS11
iHOPINTS11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:00:30 CET 2017

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