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INTS2 (integrator complex subunit 2)

Identity

Alias_namesKIAA1287
KIAA1287
Alias_symbol (synonym)INT2
Other alias
HGNC (Hugo) INTS2
LocusID (NCBI) 57508
Atlas_Id 54381
Location 17q23.2  [Link to chromosome band 17q23]
Location_base_pair Starts at 61865367 and ends at 61928032 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
INTS2 (17q23.2) / AXIN2 (17q24.1)INTS2 (17q23.2) / LIMD2 (17q23.3)INTS2 (17q23.2) / RPS6KB1 (17q23.1)
INTS2 (17q23.2) / VMP1 (17q23.1)INTS2 (17q23.2) / ZNF652 (17q21.32)INTS2 17q23.2 / AXIN2 17q24.1
INTS2 17q23.2 / LIMD2 17q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTS2   29241
Cards
Entrez_Gene (NCBI)INTS2  57508  integrator complex subunit 2
AliasesINT2; KIAA1287
GeneCards (Weizmann)INTS2
Ensembl hg19 (Hinxton)ENSG00000108506 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108506 [Gene_View]  chr17:61865367-61928032 [Contig_View]  INTS2 [Vega]
ICGC DataPortalENSG00000108506
TCGA cBioPortalINTS2
AceView (NCBI)INTS2
Genatlas (Paris)INTS2
WikiGenes57508
SOURCE (Princeton)INTS2
Genetics Home Reference (NIH)INTS2
Genomic and cartography
GoldenPath hg38 (UCSC)INTS2  -     chr17:61865367-61928032 -  17q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTS2  -     17q23.2   [Description]    (hg19-Feb_2009)
EnsemblINTS2 - 17q23.2 [CytoView hg19]  INTS2 - 17q23.2 [CytoView hg38]
Mapping of homologs : NCBIINTS2 [Mapview hg19]  INTS2 [Mapview hg38]
OMIM611346   
Gene and transcription
Genbank (Entrez)AB033113 AK299032 AK308307 AL136800 AM393379
RefSeq transcript (Entrez)NM_001330417 NM_020748
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INTS2
Cluster EST : UnigeneHs.279646 [ NCBI ]
CGAP (NCI)Hs.279646
Alternative Splicing GalleryENSG00000108506
Gene ExpressionINTS2 [ NCBI-GEO ]   INTS2 [ EBI - ARRAY_EXPRESS ]   INTS2 [ SEEK ]   INTS2 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57508
GTEX Portal (Tissue expression)INTS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0H0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0H0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0H0
Splice isoforms : SwissVarQ9H0H0
PhosPhoSitePlusQ9H0H0
Domains : Interpro (EBI)Int2_metazoa    INTS2   
Domain families : Pfam (Sanger)INTS2 (PF14750)   
Domain families : Pfam (NCBI)pfam14750   
Conserved Domain (NCBI)INTS2
DMDM Disease mutations57508
Blocks (Seattle)INTS2
SuperfamilyQ9H0H0
Human Protein AtlasENSG00000108506
Peptide AtlasQ9H0H0
HPRD11137
IPIIPI00477759   IPI01011030   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0H0
IntAct (EBI)Q9H0H0
FunCoupENSG00000108506
BioGRIDINTS2
STRING (EMBL)INTS2
ZODIACINTS2
Ontologies - Pathways
QuickGOQ9H0H0
Ontology : AmiGOprotein binding  intracellular  nucleoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  snRNA transcription from RNA polymerase II promoter  
Ontology : EGO-EBIprotein binding  intracellular  nucleoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  snRNA transcription from RNA polymerase II promoter  
NDEx NetworkINTS2
Atlas of Cancer Signalling NetworkINTS2
Wikipedia pathwaysINTS2
Orthology - Evolution
OrthoDB57508
GeneTree (enSembl)ENSG00000108506
Phylogenetic Trees/Animal Genes : TreeFamINTS2
HOVERGENQ9H0H0
HOGENOMQ9H0H0
Homologs : HomoloGeneINTS2
Homology/Alignments : Family Browser (UCSC)INTS2
Gene fusions - Rearrangements
Fusion : MitelmanINTS2/AXIN2 [17q23.2/17q24.1]  
Fusion : MitelmanINTS2/LIMD2 [17q23.2/17q23.3]  [t(17;17)(q23;q23)]  
Fusion : MitelmanINTS2/VMP1 [17q23.2/17q23.1]  [t(17;17)(q23;q23)]  
Fusion : MitelmanINTS2/ZNF652 [17q23.2/17q21.32]  [t(17;17)(q21;q23)]  
Fusion: TCGAINTS2 17q23.2 AXIN2 17q24.1 BRCA
Fusion: TCGAINTS2 17q23.2 LIMD2 17q23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS2
dbVarINTS2
ClinVarINTS2
1000_GenomesINTS2 
Exome Variant ServerINTS2
ExAC (Exome Aggregation Consortium)INTS2 (select the gene name)
Genetic variants : HAPMAP57508
Genomic Variants (DGV)INTS2 [DGVbeta]
DECIPHERINTS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTS2 
Mutations
ICGC Data PortalINTS2 
TCGA Data PortalINTS2 
Broad Tumor PortalINTS2
OASIS PortalINTS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINTS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTS2
DgiDB (Drug Gene Interaction Database)INTS2
DoCM (Curated mutations)INTS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTS2 (select a term)
intoGenINTS2
Cancer3DINTS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611346   
Orphanet
MedgenINTS2
Genetic Testing Registry INTS2
NextProtQ9H0H0 [Medical]
TSGene57508
GENETestsINTS2
Target ValidationINTS2
Huge Navigator INTS2 [HugePedia]
snp3D : Map Gene to Disease57508
BioCentury BCIQINTS2
ClinGenINTS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57508
Chemical/Pharm GKB GenePA142671605
Clinical trialINTS2
Miscellaneous
canSAR (ICR)INTS2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTS2
EVEXINTS2
GoPubMedINTS2
iHOPINTS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:04:07 CEST 2017

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