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INTS2 (integrator complex subunit 2)

Identity

Alias (NCBI)INT2
KIAA1287
HGNC (Hugo) INTS2
HGNC Alias symbINT2
HGNC Previous nameKIAA1287
HGNC Previous nameKIAA1287
LocusID (NCBI) 57508
Atlas_Id 54381
Location 17q23.2  [Link to chromosome band 17q23]
Location_base_pair Starts at 61865367 and ends at 61927982 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
INTS2 (17q23.2) / AXIN2 (17q24.1)INTS2 (17q23.2) / LIMD2 (17q23.3)INTS2 (17q23.2) / RPS6KB1 (17q23.1)
INTS2 (17q23.2) / VMP1 (17q23.1)INTS2 (17q23.2) / ZNF652 (17q21.32)INTS2 17q23.2 / AXIN2 17q24.1
INTS2 17q23.2 / LIMD2 17q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)INTS2   29241
Cards
Entrez_Gene (NCBI)INTS2    integrator complex subunit 2
AliasesINT2; KIAA1287
GeneCards (Weizmann)INTS2
Ensembl hg19 (Hinxton)ENSG00000108506 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108506 [Gene_View]  ENSG00000108506 [Sequence]  chr17:61865367-61927982 [Contig_View]  INTS2 [Vega]
ICGC DataPortalENSG00000108506
TCGA cBioPortalINTS2
AceView (NCBI)INTS2
Genatlas (Paris)INTS2
SOURCE (Princeton)INTS2
Genetics Home Reference (NIH)INTS2
Genomic and cartography
GoldenPath hg38 (UCSC)INTS2  -     chr17:61865367-61927982 -  17q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTS2  -     17q23.2   [Description]    (hg19-Feb_2009)
GoldenPathINTS2 - 17q23.2 [CytoView hg19]  INTS2 - 17q23.2 [CytoView hg38]
ImmunoBaseENSG00000108506
Genome Data Viewer NCBIINTS2 [Mapview hg19]  
OMIM611346   
Gene and transcription
Genbank (Entrez)AB033113 AK299032 AK308307 AL136800 BK005721
RefSeq transcript (Entrez)NM_001330417 NM_001351695 NM_020748
Consensus coding sequences : CCDS (NCBI)INTS2
Gene ExpressionINTS2 [ NCBI-GEO ]   INTS2 [ EBI - ARRAY_EXPRESS ]   INTS2 [ SEEK ]   INTS2 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS2 [ Firebrowse - Broad ]
GenevisibleExpression of INTS2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57508
GTEX Portal (Tissue expression)INTS2
Human Protein AtlasENSG00000108506-INTS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0H0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0H0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0H0
PhosPhoSitePlusQ9H0H0
Domains : Interpro (EBI)Int2_metazoa    INTS2   
Domain families : Pfam (Sanger)INTS2 (PF14750)   
Domain families : Pfam (NCBI)pfam14750   
Conserved Domain (NCBI)INTS2
SuperfamilyQ9H0H0
AlphaFold pdb e-kbQ9H0H0   
Human Protein Atlas [tissue]ENSG00000108506-INTS2 [tissue]
HPRD11137
Protein Interaction databases
DIP (DOE-UCLA)Q9H0H0
IntAct (EBI)Q9H0H0
BioGRIDINTS2
STRING (EMBL)INTS2
ZODIACINTS2
Ontologies - Pathways
QuickGOQ9H0H0
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  integrator complex  snRNA 3'-end processing  snRNA transcription by RNA polymerase II  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  membrane  integral component of membrane  snRNA processing  nuclear membrane  integrator complex  integrator complex  snRNA 3'-end processing  snRNA transcription by RNA polymerase II  
NDEx NetworkINTS2
Atlas of Cancer Signalling NetworkINTS2
Wikipedia pathwaysINTS2
Orthology - Evolution
OrthoDB57508
GeneTree (enSembl)ENSG00000108506
Phylogenetic Trees/Animal Genes : TreeFamINTS2
Homologs : HomoloGeneINTS2
Homology/Alignments : Family Browser (UCSC)INTS2
Gene fusions - Rearrangements
Fusion : MitelmanINTS2/AXIN2 [17q23.2/17q24.1]  
Fusion : MitelmanINTS2/LIMD2 [17q23.2/17q23.3]  
Fusion : MitelmanINTS2/VMP1 [17q23.2/17q23.1]  
Fusion : MitelmanINTS2/ZNF652 [17q23.2/17q21.32]  
Fusion : QuiverINTS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS2
dbVarINTS2
ClinVarINTS2
MonarchINTS2
1000_GenomesINTS2 
Exome Variant ServerINTS2
GNOMAD BrowserENSG00000108506
Varsome BrowserINTS2
ACMGINTS2 variants
VarityQ9H0H0
Genomic Variants (DGV)INTS2 [DGVbeta]
DECIPHERINTS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTS2 
Mutations
ICGC Data PortalINTS2 
TCGA Data PortalINTS2 
Broad Tumor PortalINTS2
OASIS PortalINTS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTS2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DINTS2
Mutations and Diseases : HGMDINTS2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaINTS2
DgiDB (Drug Gene Interaction Database)INTS2
DoCM (Curated mutations)INTS2
CIViC (Clinical Interpretations of Variants in Cancer)INTS2
Cancer3DINTS2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611346   
Orphanet
DisGeNETINTS2
MedgenINTS2
Genetic Testing Registry INTS2
NextProtQ9H0H0 [Medical]
GENETestsINTS2
Target ValidationINTS2
Huge Navigator INTS2 [HugePedia]
ClinGenINTS2
Clinical trials, drugs, therapy
MyCancerGenomeINTS2
Protein Interactions : CTDINTS2
Pharm GKB GenePA142671605
PharosQ9H0H0
Clinical trialINTS2
Miscellaneous
canSAR (ICR)INTS2
HarmonizomeINTS2
DataMed IndexINTS2
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXINTS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:14:05 CEST 2021

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