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INTS3 (integrator complex subunit 3)

Identity

Alias_namesC1orf60
chromosome 1 open reading frame 60
Alias_symbol (synonym)FLJ21919
INT3
SOSS-A
Other aliasC1orf193
SOSSA
HGNC (Hugo) INTS3
LocusID (NCBI) 65123
Atlas_Id 51127
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 153700567 and ends at 153746555 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
INTS3 (1q21.3) / CHTOP (1q21.3)INTS3 (1q21.3) / GBF1 (10q24.32)INTS3 (1q21.3) / L3MBTL4 (18p11.31)
INTS3 (1q21.3) / SLC27A3 (1q21.3)NBPF9 (1q21.1) / INTS3 (1q21.3)PPP6R2 (22q13.33) / INTS3 (1q21.3)
INTS3 1q21.3 / CHTOP 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTS3   26153
Cards
Entrez_Gene (NCBI)INTS3  65123  integrator complex subunit 3
AliasesC1orf193; C1orf60; INT3; SOSS-A; 
SOSSA
GeneCards (Weizmann)INTS3
Ensembl hg19 (Hinxton)ENSG00000143624 [Gene_View]  chr1:153700567-153746555 [Contig_View]  INTS3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143624 [Gene_View]  chr1:153700567-153746555 [Contig_View]  INTS3 [Vega]
ICGC DataPortalENSG00000143624
TCGA cBioPortalINTS3
AceView (NCBI)INTS3
Genatlas (Paris)INTS3
WikiGenes65123
SOURCE (Princeton)INTS3
Genetics Home Reference (NIH)INTS3
Genomic and cartography
GoldenPath hg19 (UCSC)INTS3  -     chr1:153700567-153746555 +  1q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)INTS3  -     1q21.3   [Description]    (hg38-Dec_2013)
EnsemblINTS3 - 1q21.3 [CytoView hg19]  INTS3 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIINTS3 [Mapview hg19]  INTS3 [Mapview hg38]
OMIM611347   
Gene and transcription
Genbank (Entrez)AF130066 AK025572 AK055174 AK074979 AK091908
RefSeq transcript (Entrez)NM_023015
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_003315905 NW_004929293
Consensus coding sequences : CCDS (NCBI)INTS3
Cluster EST : UnigeneHs.516522 [ NCBI ]
CGAP (NCI)Hs.516522
Alternative Splicing GalleryENSG00000143624
Gene ExpressionINTS3 [ NCBI-GEO ]   INTS3 [ EBI - ARRAY_EXPRESS ]   INTS3 [ SEEK ]   INTS3 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65123
GTEX Portal (Tissue expression)INTS3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68E01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68E01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68E01
Splice isoforms : SwissVarQ68E01
PhosPhoSitePlusQ68E01
Domains : Interpro (EBI)Int_cplx_su3   
Domain families : Pfam (Sanger)DUF2356 (PF10189)   
Domain families : Pfam (NCBI)pfam10189   
Conserved Domain (NCBI)INTS3
DMDM Disease mutations65123
Blocks (Seattle)INTS3
PDB (SRS)4OWT    4OWW    4OWX   
PDB (PDBSum)4OWT    4OWW    4OWX   
PDB (IMB)4OWT    4OWW    4OWX   
PDB (RSDB)4OWT    4OWW    4OWX   
Structural Biology KnowledgeBase4OWT    4OWW    4OWX   
SCOP (Structural Classification of Proteins)4OWT    4OWW    4OWX   
CATH (Classification of proteins structures)4OWT    4OWW    4OWX   
SuperfamilyQ68E01
Human Protein AtlasENSG00000143624
Peptide AtlasQ68E01
HPRD08644
IPIIPI00792312   IPI00418336   IPI00477093   IPI00645811   IPI00023389   IPI00965948   
Protein Interaction databases
DIP (DOE-UCLA)Q68E01
IntAct (EBI)Q68E01
FunCoupENSG00000143624
BioGRIDINTS3
STRING (EMBL)INTS3
ZODIACINTS3
Ontologies - Pathways
QuickGOQ68E01
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  DNA repair  cellular response to DNA damage stimulus  mitotic cell cycle checkpoint  response to ionizing radiation  snRNA processing  integrator complex  snRNA transcription from RNA polymerase II promoter  SOSS complex  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  DNA repair  cellular response to DNA damage stimulus  mitotic cell cycle checkpoint  response to ionizing radiation  snRNA processing  integrator complex  snRNA transcription from RNA polymerase II promoter  SOSS complex  
NDEx NetworkINTS3
Atlas of Cancer Signalling NetworkINTS3
Wikipedia pathwaysINTS3
Orthology - Evolution
OrthoDB65123
GeneTree (enSembl)ENSG00000143624
Phylogenetic Trees/Animal Genes : TreeFamINTS3
HOVERGENQ68E01
HOGENOMQ68E01
Homologs : HomoloGeneINTS3
Homology/Alignments : Family Browser (UCSC)INTS3
Gene fusions - Rearrangements
Fusion : MitelmanINTS3/CHTOP [1q21.3/1q21.3]  
Fusion: TCGAINTS3 1q21.3 CHTOP 1q21.3 THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS3
dbVarINTS3
ClinVarINTS3
1000_GenomesINTS3 
Exome Variant ServerINTS3
ExAC (Exome Aggregation Consortium)INTS3 (select the gene name)
Genetic variants : HAPMAP65123
Genomic Variants (DGV)INTS3 [DGVbeta]
DECIPHER (Syndromes)1:153700567-153746555  ENSG00000143624
CONAN: Copy Number AnalysisINTS3 
Mutations
ICGC Data PortalINTS3 
TCGA Data PortalINTS3 
Broad Tumor PortalINTS3
OASIS PortalINTS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTS3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINTS3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTS3
DgiDB (Drug Gene Interaction Database)INTS3
DoCM (Curated mutations)INTS3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTS3 (select a term)
intoGenINTS3
Cancer3DINTS3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611347   
Orphanet
MedgenINTS3
Genetic Testing Registry INTS3
NextProtQ68E01 [Medical]
TSGene65123
GENETestsINTS3
Huge Navigator INTS3 [HugePedia]
snp3D : Map Gene to Disease65123
BioCentury BCIQINTS3
ClinGenINTS3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65123
Chemical/Pharm GKB GenePA142672510
Clinical trialINTS3
Miscellaneous
canSAR (ICR)INTS3 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTS3
EVEXINTS3
GoPubMedINTS3
iHOPINTS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:05:21 CEST 2017

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