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INTS8 (integrator complex subunit 8)

Identity

Alias_namesC8orf52
chromosome 8 open reading frame 52
Alias_symbol (synonym)FLJ20530
INT8
MGC131633
Other alias
HGNC (Hugo) INTS8
LocusID (NCBI) 55656
Atlas_Id 64632
Location 8q22.1  [Link to chromosome band 8q22]
Location_base_pair Starts at 94823290 and ends at 94880493 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
INTS8 (8q22.1) / DPY19L4 (8q22.1)INTS8 (8q22.1) / EZR (6q25.3)INTS8 (8q22.1) / RP11-219B4.5 ()
INTS8 (8q22.1) / TALDO1 (11p15.5)INTS8 DPY19L4INTS8 RP11-219B4.5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTS8   26048
Cards
Entrez_Gene (NCBI)INTS8  55656  integrator complex subunit 8
AliasesC8orf52; INT8
GeneCards (Weizmann)INTS8
Ensembl hg19 (Hinxton)ENSG00000164941 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164941 [Gene_View]  chr8:94823290-94880493 [Contig_View]  INTS8 [Vega]
ICGC DataPortalENSG00000164941
TCGA cBioPortalINTS8
AceView (NCBI)INTS8
Genatlas (Paris)INTS8
WikiGenes55656
SOURCE (Princeton)INTS8
Genetics Home Reference (NIH)INTS8
Genomic and cartography
GoldenPath hg38 (UCSC)INTS8  -     chr8:94823290-94880493 +  8q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTS8  -     8q22.1   [Description]    (hg19-Feb_2009)
EnsemblINTS8 - 8q22.1 [CytoView hg19]  INTS8 - 8q22.1 [CytoView hg38]
Mapping of homologs : NCBIINTS8 [Mapview hg19]  INTS8 [Mapview hg38]
OMIM611351   
Gene and transcription
Genbank (Entrez)AB161944 AK000537 AK001403 AK091278 AK225533
RefSeq transcript (Entrez)NM_017864
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INTS8
Cluster EST : UnigeneHs.727669 [ NCBI ]
CGAP (NCI)Hs.727669
Alternative Splicing GalleryENSG00000164941
Gene ExpressionINTS8 [ NCBI-GEO ]   INTS8 [ EBI - ARRAY_EXPRESS ]   INTS8 [ SEEK ]   INTS8 [ MEM ]
Gene Expression Viewer (FireBrowse)INTS8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55656
GTEX Portal (Tissue expression)INTS8
Human Protein AtlasENSG00000164941-INTS8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ75QN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ75QN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ75QN2
Splice isoforms : SwissVarQ75QN2
PhosPhoSitePlusQ75QN2
Domains : Interpro (EBI)TPR-like_helical_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)INTS8
DMDM Disease mutations55656
Blocks (Seattle)INTS8
SuperfamilyQ75QN2
Human Protein Atlas [tissue]ENSG00000164941-INTS8 [tissue]
Peptide AtlasQ75QN2
HPRD08626
IPIIPI00375653   IPI00797345   IPI00981328   IPI00973738   IPI00979170   IPI00974267   IPI00981803   IPI00980667   IPI00984573   IPI00976989   
Protein Interaction databases
DIP (DOE-UCLA)Q75QN2
IntAct (EBI)Q75QN2
FunCoupENSG00000164941
BioGRIDINTS8
STRING (EMBL)INTS8
ZODIACINTS8
Ontologies - Pathways
QuickGOQ75QN2
Ontology : AmiGOprotein binding  nucleoplasm  snRNA processing  integrator complex  snRNA transcription from RNA polymerase II promoter  
Ontology : EGO-EBIprotein binding  nucleoplasm  snRNA processing  integrator complex  snRNA transcription from RNA polymerase II promoter  
NDEx NetworkINTS8
Atlas of Cancer Signalling NetworkINTS8
Wikipedia pathwaysINTS8
Orthology - Evolution
OrthoDB55656
GeneTree (enSembl)ENSG00000164941
Phylogenetic Trees/Animal Genes : TreeFamINTS8
HOVERGENQ75QN2
HOGENOMQ75QN2
Homologs : HomoloGeneINTS8
Homology/Alignments : Family Browser (UCSC)INTS8
Gene fusions - Rearrangements
Fusion: TCGAINTS8 DPY19L4
Fusion: TCGAINTS8 RP11-219B4.5
Fusion: Tumor Portal INTS8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTS8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTS8
dbVarINTS8
ClinVarINTS8
1000_GenomesINTS8 
Exome Variant ServerINTS8
ExAC (Exome Aggregation Consortium)ENSG00000164941
GNOMAD BrowserENSG00000164941
Genetic variants : HAPMAP55656
Genomic Variants (DGV)INTS8 [DGVbeta]
DECIPHERINTS8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTS8 
Mutations
ICGC Data PortalINTS8 
TCGA Data PortalINTS8 
Broad Tumor PortalINTS8
OASIS PortalINTS8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTS8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINTS8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTS8
DgiDB (Drug Gene Interaction Database)INTS8
DoCM (Curated mutations)INTS8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTS8 (select a term)
intoGenINTS8
Cancer3DINTS8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611351   
Orphanet
MedgenINTS8
Genetic Testing Registry INTS8
NextProtQ75QN2 [Medical]
TSGene55656
GENETestsINTS8
Target ValidationINTS8
Huge Navigator INTS8 [HugePedia]
snp3D : Map Gene to Disease55656
BioCentury BCIQINTS8
ClinGenINTS8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55656
Chemical/Pharm GKB GenePA142672371
Clinical trialINTS8
Miscellaneous
canSAR (ICR)INTS8 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTS8
EVEXINTS8
GoPubMedINTS8
iHOPINTS8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:51:38 CET 2017

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