INTS8 (integrator complex subunit 8)

2014-11-01  

Identity

HGNC
INTS8
LOCATION
8q22.1
LOCUSID
55656
ALIAS
C8orf52,INT8,NEDCHS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55656
MIM: 611351
HGNC: 26048
Ensembl: ENSG00000164941

Variants:

dbSNP: 55656
ClinVar: 55656
TCGA: ENSG00000164941
COSMIC: INTS8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164941ENST00000343161J3KNV5
ENSG00000164941ENST00000519053E5RJL5
ENSG00000164941ENST00000519457E5RJF0
ENSG00000164941ENST00000520315H0YC12
ENSG00000164941ENST00000520526H0YBS1
ENSG00000164941ENST00000521860H0YBQ1
ENSG00000164941ENST00000522171E5RIN8
ENSG00000164941ENST00000523206E5RG48
ENSG00000164941ENST00000523731Q75QN2
ENSG00000164941ENST00000523808E5RH10
ENSG00000164941ENST00000524333E5RG48

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
285421702017Human mutations in integrator complex subunits link transcriptome integrity to brain development.15

Citation

Dessen P

INTS8 (integrator complex subunit 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64632/ints8