Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

INTU (inturned planar cell polarity protein)

Identity

Alias_namesPDZK6
PDZD6
PDZ domain containing 6
inturned planar cell polarity effector homolog (Drosophila)
Alias_symbol (synonym)KIAA1284
Other aliasINT
HGNC (Hugo) INTU
LocusID (NCBI) 27152
Atlas_Id 56034
Location 4q28.1  [Link to chromosome band 4q28]
Location_base_pair Starts at 127632932 and ends at 127716779 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INTU   29239
Cards
Entrez_Gene (NCBI)INTU  27152  inturned planar cell polarity protein
AliasesINT; PDZD6; PDZK6
GeneCards (Weizmann)INTU
Ensembl hg19 (Hinxton)ENSG00000164066 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164066 [Gene_View]  chr4:127632932-127716779 [Contig_View]  INTU [Vega]
ICGC DataPortalENSG00000164066
TCGA cBioPortalINTU
AceView (NCBI)INTU
Genatlas (Paris)INTU
WikiGenes27152
SOURCE (Princeton)INTU
Genetics Home Reference (NIH)INTU
Genomic and cartography
GoldenPath hg38 (UCSC)INTU  -     chr4:127632932-127716779 +  4q28.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)INTU  -     4q28.1   [Description]    (hg19-Feb_2009)
EnsemblINTU - 4q28.1 [CytoView hg19]  INTU - 4q28.1 [CytoView hg38]
Mapping of homologs : NCBIINTU [Mapview hg19]  INTU [Mapview hg38]
OMIM610621   
Gene and transcription
Genbank (Entrez)AB033110 AK123320 AK291481 BC051698 BC130611
RefSeq transcript (Entrez)NM_015693
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)INTU
Cluster EST : UnigeneHs.391481 [ NCBI ]
CGAP (NCI)Hs.391481
Alternative Splicing GalleryENSG00000164066
Gene ExpressionINTU [ NCBI-GEO ]   INTU [ EBI - ARRAY_EXPRESS ]   INTU [ SEEK ]   INTU [ MEM ]
Gene Expression Viewer (FireBrowse)INTU [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27152
GTEX Portal (Tissue expression)INTU
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULD6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULD6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULD6
Splice isoforms : SwissVarQ9ULD6
PhosPhoSitePlusQ9ULD6
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)PDZ   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)INTU
DMDM Disease mutations27152
Blocks (Seattle)INTU
SuperfamilyQ9ULD6
Human Protein AtlasENSG00000164066
Peptide AtlasQ9ULD6
HPRD15113
IPIIPI00384458   IPI00008057   IPI00964653   IPI00967211   IPI00967518   IPI00965704   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULD6
IntAct (EBI)Q9ULD6
FunCoupENSG00000164066
BioGRIDINTU
STRING (EMBL)INTU
ZODIACINTU
Ontologies - Pathways
QuickGOQ9ULD6
Ontology : AmiGOprotein binding  cytoplasm  nervous system development  regulation of smoothened signaling pathway  cell surface  negative regulation of keratinocyte proliferation  spinal cord dorsal/ventral patterning  neural tube development  keratinocyte differentiation  regulation of ossification  hair follicle morphogenesis  motile cilium  ciliary basal body  embryonic digit morphogenesis  motile cilium assembly  positive regulation of smoothened signaling pathway  negative regulation of cell division  limb development  cilium assembly  non-motile cilium assembly  
Ontology : EGO-EBIprotein binding  cytoplasm  nervous system development  regulation of smoothened signaling pathway  cell surface  negative regulation of keratinocyte proliferation  spinal cord dorsal/ventral patterning  neural tube development  keratinocyte differentiation  regulation of ossification  hair follicle morphogenesis  motile cilium  ciliary basal body  embryonic digit morphogenesis  motile cilium assembly  positive regulation of smoothened signaling pathway  negative regulation of cell division  limb development  cilium assembly  non-motile cilium assembly  
NDEx NetworkINTU
Atlas of Cancer Signalling NetworkINTU
Wikipedia pathwaysINTU
Orthology - Evolution
OrthoDB27152
GeneTree (enSembl)ENSG00000164066
Phylogenetic Trees/Animal Genes : TreeFamINTU
HOVERGENQ9ULD6
HOGENOMQ9ULD6
Homologs : HomoloGeneINTU
Homology/Alignments : Family Browser (UCSC)INTU
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINTU [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INTU
dbVarINTU
ClinVarINTU
1000_GenomesINTU 
Exome Variant ServerINTU
ExAC (Exome Aggregation Consortium)INTU (select the gene name)
Genetic variants : HAPMAP27152
Genomic Variants (DGV)INTU [DGVbeta]
DECIPHERINTU [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisINTU 
Mutations
ICGC Data PortalINTU 
TCGA Data PortalINTU 
Broad Tumor PortalINTU
OASIS PortalINTU [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINTU  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINTU
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INTU
DgiDB (Drug Gene Interaction Database)INTU
DoCM (Curated mutations)INTU (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INTU (select a term)
intoGenINTU
Cancer3DINTU(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610621   
Orphanet
MedgenINTU
Genetic Testing Registry INTU
NextProtQ9ULD6 [Medical]
TSGene27152
GENETestsINTU
Target ValidationINTU
Huge Navigator INTU [HugePedia]
snp3D : Map Gene to Disease27152
BioCentury BCIQINTU
ClinGenINTU
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27152
Chemical/Pharm GKB GenePA162392193
Clinical trialINTU
Miscellaneous
canSAR (ICR)INTU (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINTU
EVEXINTU
GoPubMedINTU
iHOPINTU
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:38:41 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.