IP6K3 (inositol hexakisphosphate kinase 3)

2004-04-01  

Identity

HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
IHPK3,INSP6K3

Other Information

Locus ID:

NCBI: 117283
MIM: 606993
HGNC: 17269
Ensembl: ENSG00000161896

Variants:

dbSNP: 117283
ClinVar: 117283
TCGA: ENSG00000161896
COSMIC: IP6K3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161896ENST00000293756Q96PC2
ENSG00000161896ENST00000293756Q5TAQ4
ENSG00000161896ENST00000451316Q96PC2
ENSG00000161896ENST00000451316Q5TAQ4
ENSG00000161896ENST00000634274A0A0U1RRE0

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Phosphatidylinositol signaling systemKEGGko04070
Phosphatidylinositol signaling systemKEGGhsa04070
MetabolismREACTOMER-HSA-1430728
Inositol phosphate metabolismREACTOMER-HSA-1483249
Synthesis of pyrophosphates in the cytosolREACTOMER-HSA-1855167

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
275771082016Inositol Hexakisphosphate Kinase 3 Regulates Metabolism and Lifespan in Mice.14
273452652016Contribution of polymorphic variation of inositol hexakisphosphate kinase 3 (IP6K3) gene promoter to the susceptibility to late onset Alzheimer's disease.8

Citation

Dessen P

IP6K3 (inositol hexakisphosphate kinase 3)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/40937/ip6k3