IPO4 (importin 4)

2010-11-01 Affiliation

Identity

HGNC

IPO4

LOCATION

14q12

LOCUSID

79711

ALIAS

Imp4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79711
HGNC: 19426
Ensembl: ENSG00000196497

Variants:

dbSNP: 79711
ClinVar: 79711
TCGA: ENSG00000196497
COSMIC: IPO4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196497	ENST00000354464	Q8TEX9
ENSG00000196497	ENST00000558046	H0YKG5
ENSG00000196497	ENST00000558233	H0YN07
ENSG00000196497	ENST00000558780	H0YL92
ENSG00000196497	ENST00000559253	H0YLV0
ENSG00000196497	ENST00000560155	H0YN14
ENSG00000196497	ENST00000561034	H0YK93
ENSG00000196497	ENST00000561462	H0YMR4
ENSG00000196497	ENST00000625289	H0YLV0

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19788888	2009	Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.	21
20805509	2010	CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.	16
16207705	2005	Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor.	13
27528606	2016	Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.	12
28254634	2017	Competitive regulation of IPO4 transcription by ELK1 and GABP.	2

Citation

Dessen P

IPO4 (importin 4)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51761/ipo4