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IRF2BPL (interferon regulatory factor 2 binding protein like)

Identity

Alias_namesC14orf4
chromosome 14 open reading frame 4
interferon regulatory factor 2 binding protein-like
Alias_symbol (synonym)EAP1
KIAA1865
Other alias
HGNC (Hugo) IRF2BPL
LocusID (NCBI) 64207
Atlas_Id 64663
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 77024543 and ends at 77028699 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IRF2BPL   14282
Cards
Entrez_Gene (NCBI)IRF2BPL  64207  interferon regulatory factor 2 binding protein like
AliasesC14orf4; EAP1
GeneCards (Weizmann)IRF2BPL
Ensembl hg19 (Hinxton)ENSG00000119669 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119669 [Gene_View]  chr14:77024543-77028699 [Contig_View]  IRF2BPL [Vega]
ICGC DataPortalENSG00000119669
TCGA cBioPortalIRF2BPL
AceView (NCBI)IRF2BPL
Genatlas (Paris)IRF2BPL
WikiGenes64207
SOURCE (Princeton)IRF2BPL
Genetics Home Reference (NIH)IRF2BPL
Genomic and cartography
GoldenPath hg38 (UCSC)IRF2BPL  -     chr14:77024543-77028699 -  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IRF2BPL  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblIRF2BPL - 14q24.3 [CytoView hg19]  IRF2BPL - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBIIRF2BPL [Mapview hg19]  IRF2BPL [Mapview hg38]
OMIM611720   
Gene and transcription
Genbank (Entrez)AB058768 AF063597 AF075110 AI377523 AI821684
RefSeq transcript (Entrez)NM_024496
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IRF2BPL
Cluster EST : UnigeneHs.745194 [ NCBI ]
CGAP (NCI)Hs.745194
Alternative Splicing GalleryENSG00000119669
Gene ExpressionIRF2BPL [ NCBI-GEO ]   IRF2BPL [ EBI - ARRAY_EXPRESS ]   IRF2BPL [ SEEK ]   IRF2BPL [ MEM ]
Gene Expression Viewer (FireBrowse)IRF2BPL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64207
GTEX Portal (Tissue expression)IRF2BPL
Human Protein AtlasENSG00000119669-IRF2BPL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1B7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1B7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1B7
Splice isoforms : SwissVarQ9H1B7
PhosPhoSitePlusQ9H1B7
Domains : Interpro (EBI)Interferon_reg_fac2-bd1_2_Znf   
Domain families : Pfam (Sanger)IRF-2BP1_2 (PF11261)   
Domain families : Pfam (NCBI)pfam11261   
Conserved Domain (NCBI)IRF2BPL
DMDM Disease mutations64207
Blocks (Seattle)IRF2BPL
PDB (SRS)2B9G    2CS3   
PDB (PDBSum)2B9G    2CS3   
PDB (IMB)2B9G    2CS3   
PDB (RSDB)2B9G    2CS3   
Structural Biology KnowledgeBase2B9G    2CS3   
SCOP (Structural Classification of Proteins)2B9G    2CS3   
CATH (Classification of proteins structures)2B9G    2CS3   
SuperfamilyQ9H1B7
Human Protein Atlas [tissue]ENSG00000119669-IRF2BPL [tissue]
Peptide AtlasQ9H1B7
HPRD10713
IPIIPI00019205   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1B7
IntAct (EBI)Q9H1B7
FunCoupENSG00000119669
BioGRIDIRF2BPL
STRING (EMBL)IRF2BPL
ZODIACIRF2BPL
Ontologies - Pathways
QuickGOQ9H1B7
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  molecular_function  extracellular space  nucleus  nucleus  nucleoplasm  zinc ion binding  positive regulation of transcription from RNA polymerase II promoter  development of secondary female sexual characteristics  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  molecular_function  extracellular space  nucleus  nucleus  nucleoplasm  zinc ion binding  positive regulation of transcription from RNA polymerase II promoter  development of secondary female sexual characteristics  
NDEx NetworkIRF2BPL
Atlas of Cancer Signalling NetworkIRF2BPL
Wikipedia pathwaysIRF2BPL
Orthology - Evolution
OrthoDB64207
GeneTree (enSembl)ENSG00000119669
Phylogenetic Trees/Animal Genes : TreeFamIRF2BPL
HOVERGENQ9H1B7
HOGENOMQ9H1B7
Homologs : HomoloGeneIRF2BPL
Homology/Alignments : Family Browser (UCSC)IRF2BPL
Gene fusions - Rearrangements
Fusion: Tumor Portal IRF2BPL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIRF2BPL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IRF2BPL
dbVarIRF2BPL
ClinVarIRF2BPL
1000_GenomesIRF2BPL 
Exome Variant ServerIRF2BPL
ExAC (Exome Aggregation Consortium)ENSG00000119669
GNOMAD BrowserENSG00000119669
Genetic variants : HAPMAP64207
Genomic Variants (DGV)IRF2BPL [DGVbeta]
DECIPHERIRF2BPL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIRF2BPL 
Mutations
ICGC Data PortalIRF2BPL 
TCGA Data PortalIRF2BPL 
Broad Tumor PortalIRF2BPL
OASIS PortalIRF2BPL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIRF2BPL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIRF2BPL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IRF2BPL
DgiDB (Drug Gene Interaction Database)IRF2BPL
DoCM (Curated mutations)IRF2BPL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IRF2BPL (select a term)
intoGenIRF2BPL
Cancer3DIRF2BPL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611720   
Orphanet
MedgenIRF2BPL
Genetic Testing Registry IRF2BPL
NextProtQ9H1B7 [Medical]
TSGene64207
GENETestsIRF2BPL
Target ValidationIRF2BPL
Huge Navigator IRF2BPL [HugePedia]
snp3D : Map Gene to Disease64207
BioCentury BCIQIRF2BPL
ClinGenIRF2BPL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64207
Chemical/Pharm GKB GenePA25516
Clinical trialIRF2BPL
Miscellaneous
canSAR (ICR)IRF2BPL (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIRF2BPL
EVEXIRF2BPL
GoPubMedIRF2BPL
iHOPIRF2BPL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:51:44 CET 2017

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