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IRF9 (interferon regulatory factor 9)

Identity

Alias_namesISGF3G
interferon-stimulated transcription factor 3, gamma (48kD)
interferon-stimulated transcription factor 3, gamma 48kDa
Other aliasIRF-9
ISGF3
p48
HGNC (Hugo) IRF9
LocusID (NCBI) 10379
Atlas_Id 51547
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24161213 and ends at 24166566 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IRF9   6131
Cards
Entrez_Gene (NCBI)IRF9  10379  interferon regulatory factor 9
AliasesIRF-9; ISGF3; ISGF3G; p48
GeneCards (Weizmann)IRF9
Ensembl hg19 (Hinxton)ENSG00000213928 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213928 [Gene_View]  chr14:24161213-24166566 [Contig_View]  IRF9 [Vega]
ICGC DataPortalENSG00000213928
TCGA cBioPortalIRF9
AceView (NCBI)IRF9
Genatlas (Paris)IRF9
WikiGenes10379
SOURCE (Princeton)IRF9
Genetics Home Reference (NIH)IRF9
Genomic and cartography
GoldenPath hg38 (UCSC)IRF9  -     chr14:24161213-24166566 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IRF9  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblIRF9 - 14q12 [CytoView hg19]  IRF9 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIIRF9 [Mapview hg19]  IRF9 [Mapview hg38]
OMIM147574   
Gene and transcription
Genbank (Entrez)AK295467 AK308347 BC035716 BI497082 BI919023
RefSeq transcript (Entrez)NM_006084
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IRF9
Cluster EST : UnigeneHs.1706 [ NCBI ]
CGAP (NCI)Hs.1706
Alternative Splicing GalleryENSG00000213928
Gene ExpressionIRF9 [ NCBI-GEO ]   IRF9 [ EBI - ARRAY_EXPRESS ]   IRF9 [ SEEK ]   IRF9 [ MEM ]
Gene Expression Viewer (FireBrowse)IRF9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10379
GTEX Portal (Tissue expression)IRF9
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ00978   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00978  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00978
Splice isoforms : SwissVarQ00978
PhosPhoSitePlusQ00978
Domaine pattern : Prosite (Expaxy)IRF_1 (PS00601)    IRF_2 (PS51507)   
Domains : Interpro (EBI)Interferon_reg_fac_CS    Interferon_reg_fact_DNA-bd_dom    Interferon_reg_factor-3    SMAD_dom-like    SMAD_FHA_domain    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)IRF (PF00605)    IRF-3 (PF10401)   
Domain families : Pfam (NCBI)pfam00605    pfam10401   
Domain families : Smart (EMBL)IRF (SM00348)  IRF-3 (SM01243)  
Conserved Domain (NCBI)IRF9
DMDM Disease mutations10379
Blocks (Seattle)IRF9
SuperfamilyQ00978
Human Protein AtlasENSG00000213928
Peptide AtlasQ00978
HPRD00960
IPIIPI00025478   IPI00797479   
Protein Interaction databases
DIP (DOE-UCLA)Q00978
IntAct (EBI)Q00978
FunCoupENSG00000213928
BioGRIDIRF9
STRING (EMBL)IRF9
ZODIACIRF9
Ontologies - Pathways
QuickGOQ00978
Ontology : AmiGOcore promoter binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  cell surface receptor signaling pathway  defense response to virus  interferon-gamma-mediated signaling pathway  type I interferon signaling pathway  
Ontology : EGO-EBIcore promoter binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  cell surface receptor signaling pathway  defense response to virus  interferon-gamma-mediated signaling pathway  type I interferon signaling pathway  
Pathways : BIOCARTABone Remodelling [Genes]    IFN alpha signaling pathway [Genes]   
Pathways : KEGGOsteoclast differentiation    Jak-STAT signaling pathway    Hepatitis C    Measles    Influenza A    Herpes simplex infection    Viral carcinogenesis   
NDEx NetworkIRF9
Atlas of Cancer Signalling NetworkIRF9
Wikipedia pathwaysIRF9
Orthology - Evolution
OrthoDB10379
GeneTree (enSembl)ENSG00000213928
Phylogenetic Trees/Animal Genes : TreeFamIRF9
HOVERGENQ00978
HOGENOMQ00978
Homologs : HomoloGeneIRF9
Homology/Alignments : Family Browser (UCSC)IRF9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIRF9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IRF9
dbVarIRF9
ClinVarIRF9
1000_GenomesIRF9 
Exome Variant ServerIRF9
ExAC (Exome Aggregation Consortium)IRF9 (select the gene name)
Genetic variants : HAPMAP10379
Genomic Variants (DGV)IRF9 [DGVbeta]
DECIPHERIRF9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIRF9 
Mutations
ICGC Data PortalIRF9 
TCGA Data PortalIRF9 
Broad Tumor PortalIRF9
OASIS PortalIRF9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIRF9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIRF9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IRF9
DgiDB (Drug Gene Interaction Database)IRF9
DoCM (Curated mutations)IRF9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IRF9 (select a term)
intoGenIRF9
Cancer3DIRF9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147574   
Orphanet
MedgenIRF9
Genetic Testing Registry IRF9
NextProtQ00978 [Medical]
TSGene10379
GENETestsIRF9
Target ValidationIRF9
Huge Navigator IRF9 [HugePedia]
snp3D : Map Gene to Disease10379
BioCentury BCIQIRF9
ClinGenIRF9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10379
Chemical/Pharm GKB GenePA162392259
Clinical trialIRF9
Miscellaneous
canSAR (ICR)IRF9 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIRF9
EVEXIRF9
GoPubMedIRF9
iHOPIRF9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:38:48 CEST 2017

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