Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IRGC (immunity related GTPase cinema)

Identity

Alias_namesIRGC1
immunity-related GTPase family, cinema 1
Alias_symbol (synonym)Iigp5
CINEMA
Other aliasIFGGE
R30953_1
HGNC (Hugo) IRGC
LocusID (NCBI) 56269
Atlas_Id 64664
Location 19q13.31  [Link to chromosome band 19q13]
Location_base_pair Starts at 43716062 and ends at 43720017 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IRGC   28835
Cards
Entrez_Gene (NCBI)IRGC  56269  immunity related GTPase cinema
AliasesCINEMA; IFGGE; IRGC1; Iigp5; 
R30953_1
GeneCards (Weizmann)IRGC
Ensembl hg19 (Hinxton)ENSG00000124449 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124449 [Gene_View]  chr19:43716062-43720017 [Contig_View]  IRGC [Vega]
ICGC DataPortalENSG00000124449
TCGA cBioPortalIRGC
AceView (NCBI)IRGC
Genatlas (Paris)IRGC
WikiGenes56269
SOURCE (Princeton)IRGC
Genetics Home Reference (NIH)IRGC
Genomic and cartography
GoldenPath hg38 (UCSC)IRGC  -     chr19:43716062-43720017 +  19q13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IRGC  -     19q13.31   [Description]    (hg19-Feb_2009)
EnsemblIRGC - 19q13.31 [CytoView hg19]  IRGC - 19q13.31 [CytoView hg38]
Mapping of homologs : NCBIIRGC [Mapview hg19]  IRGC [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC033853 BC066939
RefSeq transcript (Entrez)NM_019612
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IRGC
Cluster EST : UnigeneHs.515444 [ NCBI ]
CGAP (NCI)Hs.515444
Alternative Splicing GalleryENSG00000124449
Gene ExpressionIRGC [ NCBI-GEO ]   IRGC [ EBI - ARRAY_EXPRESS ]   IRGC [ SEEK ]   IRGC [ MEM ]
Gene Expression Viewer (FireBrowse)IRGC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56269
GTEX Portal (Tissue expression)IRGC
Human Protein AtlasENSG00000124449-IRGC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6NXR0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6NXR0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6NXR0
Splice isoforms : SwissVarQ6NXR0
Catalytic activity : Enzyme3.6.5.- [ Enzyme-Expasy ]   3.6.5.-3.6.5.- [ IntEnz-EBI ]   3.6.5.- [ BRENDA ]   3.6.5.- [ KEGG ]   
PhosPhoSitePlusQ6NXR0
Domaine pattern : Prosite (Expaxy)G_IRG (PS51716)   
Domains : Interpro (EBI)G_IRG_dom    Immunity-related_GTPase-like    P-loop_NTPase   
Domain families : Pfam (Sanger)IIGP (PF05049)   
Domain families : Pfam (NCBI)pfam05049   
Conserved Domain (NCBI)IRGC
DMDM Disease mutations56269
Blocks (Seattle)IRGC
SuperfamilyQ6NXR0
Human Protein Atlas [tissue]ENSG00000124449-IRGC [tissue]
Peptide AtlasQ6NXR0
HPRD15200
IPIIPI00021328   
Protein Interaction databases
DIP (DOE-UCLA)Q6NXR0
IntAct (EBI)Q6NXR0
FunCoupENSG00000124449
BioGRIDIRGC
STRING (EMBL)IRGC
ZODIACIRGC
Ontologies - Pathways
QuickGOQ6NXR0
Ontology : AmiGOGTPase activity  GTP binding  membrane  
Ontology : EGO-EBIGTPase activity  GTP binding  membrane  
NDEx NetworkIRGC
Atlas of Cancer Signalling NetworkIRGC
Wikipedia pathwaysIRGC
Orthology - Evolution
OrthoDB56269
GeneTree (enSembl)ENSG00000124449
Phylogenetic Trees/Animal Genes : TreeFamIRGC
HOVERGENQ6NXR0
HOGENOMQ6NXR0
Homologs : HomoloGeneIRGC
Homology/Alignments : Family Browser (UCSC)IRGC
Gene fusions - Rearrangements
Tumor Fusion PortalIRGC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIRGC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IRGC
dbVarIRGC
ClinVarIRGC
1000_GenomesIRGC 
Exome Variant ServerIRGC
ExAC (Exome Aggregation Consortium)ENSG00000124449
GNOMAD BrowserENSG00000124449
Genetic variants : HAPMAP56269
Genomic Variants (DGV)IRGC [DGVbeta]
DECIPHERIRGC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIRGC 
Mutations
ICGC Data PortalIRGC 
TCGA Data PortalIRGC 
Broad Tumor PortalIRGC
OASIS PortalIRGC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIRGC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIRGC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IRGC
DgiDB (Drug Gene Interaction Database)IRGC
DoCM (Curated mutations)IRGC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IRGC (select a term)
intoGenIRGC
Cancer3DIRGC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETIRGC
MedgenIRGC
Genetic Testing Registry IRGC
NextProtQ6NXR0 [Medical]
TSGene56269
GENETestsIRGC
Target ValidationIRGC
Huge Navigator IRGC [HugePedia]
snp3D : Map Gene to Disease56269
BioCentury BCIQIRGC
ClinGenIRGC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56269
Chemical/Pharm GKB GenePA142671651
Clinical trialIRGC
Miscellaneous
canSAR (ICR)IRGC (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIRGC
EVEXIRGC
GoPubMedIRGC
iHOPIRGC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:38:44 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.