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IRX1 (iroquois homeobox 1)

Identity

Alias_symbol (synonym)IRX-5
Other aliasIRXA1
HGNC (Hugo) IRX1
LocusID (NCBI) 79192
Atlas_Id 50333
Location 5p15.33  [Link to chromosome band 5p15]
Location_base_pair Starts at 3596054 and ends at 3601403 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IRX1   14358
Cards
Entrez_Gene (NCBI)IRX1  79192  iroquois homeobox 1
AliasesIRX-5; IRXA1
GeneCards (Weizmann)IRX1
Ensembl hg19 (Hinxton)ENSG00000170549 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170549 [Gene_View]  chr5:3596054-3601403 [Contig_View]  IRX1 [Vega]
ICGC DataPortalENSG00000170549
TCGA cBioPortalIRX1
AceView (NCBI)IRX1
Genatlas (Paris)IRX1
WikiGenes79192
SOURCE (Princeton)IRX1
Genetics Home Reference (NIH)IRX1
Genomic and cartography
GoldenPath hg38 (UCSC)IRX1  -     chr5:3596054-3601403 +  5p15.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IRX1  -     5p15.33   [Description]    (hg19-Feb_2009)
EnsemblIRX1 - 5p15.33 [CytoView hg19]  IRX1 - 5p15.33 [CytoView hg38]
Mapping of homologs : NCBIIRX1 [Mapview hg19]  IRX1 [Mapview hg38]
OMIM606197   
Gene and transcription
Genbank (Entrez)AY335938 BC029160 BC166635 U90307
RefSeq transcript (Entrez)NM_024337
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IRX1
Cluster EST : UnigeneHs.424156 [ NCBI ]
CGAP (NCI)Hs.424156
Alternative Splicing GalleryENSG00000170549
Gene ExpressionIRX1 [ NCBI-GEO ]   IRX1 [ EBI - ARRAY_EXPRESS ]   IRX1 [ SEEK ]   IRX1 [ MEM ]
Gene Expression Viewer (FireBrowse)IRX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79192
GTEX Portal (Tissue expression)IRX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78414   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78414  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78414
Splice isoforms : SwissVarP78414
PhosPhoSitePlusP78414
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_KN_domain    Iroquois_homeo   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  IRO (SM00548)  
Conserved Domain (NCBI)IRX1
DMDM Disease mutations79192
Blocks (Seattle)IRX1
SuperfamilyP78414
Human Protein AtlasENSG00000170549
Peptide AtlasP78414
HPRD16203
IPIIPI00375629   
Protein Interaction databases
DIP (DOE-UCLA)P78414
IntAct (EBI)P78414
FunCoupENSG00000170549
BioGRIDIRX1
STRING (EMBL)IRX1
ZODIACIRX1
Ontologies - Pathways
QuickGOP78414
Ontology : AmiGOnucleus  regulation of transcription, DNA-templated  sequence-specific DNA binding  specification of loop of Henle identity  proximal/distal pattern formation involved in metanephric nephron development  
Ontology : EGO-EBInucleus  regulation of transcription, DNA-templated  sequence-specific DNA binding  specification of loop of Henle identity  proximal/distal pattern formation involved in metanephric nephron development  
NDEx NetworkIRX1
Atlas of Cancer Signalling NetworkIRX1
Wikipedia pathwaysIRX1
Orthology - Evolution
OrthoDB79192
GeneTree (enSembl)ENSG00000170549
Phylogenetic Trees/Animal Genes : TreeFamIRX1
HOVERGENP78414
HOGENOMP78414
Homologs : HomoloGeneIRX1
Homology/Alignments : Family Browser (UCSC)IRX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIRX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IRX1
dbVarIRX1
ClinVarIRX1
1000_GenomesIRX1 
Exome Variant ServerIRX1
ExAC (Exome Aggregation Consortium)IRX1 (select the gene name)
Genetic variants : HAPMAP79192
Genomic Variants (DGV)IRX1 [DGVbeta]
DECIPHERIRX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIRX1 
Mutations
ICGC Data PortalIRX1 
TCGA Data PortalIRX1 
Broad Tumor PortalIRX1
OASIS PortalIRX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIRX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIRX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IRX1
DgiDB (Drug Gene Interaction Database)IRX1
DoCM (Curated mutations)IRX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IRX1 (select a term)
intoGenIRX1
Cancer3DIRX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606197   
Orphanet
MedgenIRX1
Genetic Testing Registry IRX1
NextProtP78414 [Medical]
TSGene79192
GENETestsIRX1
Target ValidationIRX1
Huge Navigator IRX1 [HugePedia]
snp3D : Map Gene to Disease79192
BioCentury BCIQIRX1
ClinGenIRX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79192
Chemical/Pharm GKB GenePA29924
Clinical trialIRX1
Miscellaneous
canSAR (ICR)IRX1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIRX1
EVEXIRX1
GoPubMedIRX1
iHOPIRX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:13:39 CEST 2017

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