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IRX6 (iroquois homeobox 6)

Identity

Alias_namesIRX7
iroquois homeobox protein 7
iroquois homeobox protein 6
Alias_symbol (synonym)IRX-3
Other aliasIRXB3
HGNC (Hugo) IRX6
LocusID (NCBI) 79190
Atlas_Id 64666
Location 16q12.2  [Link to chromosome band 16q12]
Location_base_pair Starts at 55324559 and ends at 55330760 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IRX6 (16q12.2) / HLA-DRB1 (6p21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IRX6   14675
Cards
Entrez_Gene (NCBI)IRX6  79190  iroquois homeobox 6
AliasesIRX-3; IRX7; IRXB3
GeneCards (Weizmann)IRX6
Ensembl hg19 (Hinxton)ENSG00000159387 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159387 [Gene_View]  chr16:55324559-55330760 [Contig_View]  IRX6 [Vega]
ICGC DataPortalENSG00000159387
TCGA cBioPortalIRX6
AceView (NCBI)IRX6
Genatlas (Paris)IRX6
WikiGenes79190
SOURCE (Princeton)IRX6
Genetics Home Reference (NIH)IRX6
Genomic and cartography
GoldenPath hg38 (UCSC)IRX6  -     chr16:55324559-55330760 +  16q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IRX6  -     16q12.2   [Description]    (hg19-Feb_2009)
EnsemblIRX6 - 16q12.2 [CytoView hg19]  IRX6 - 16q12.2 [CytoView hg38]
Mapping of homologs : NCBIIRX6 [Mapview hg19]  IRX6 [Mapview hg38]
OMIM606196   
Gene and transcription
Genbank (Entrez)AK125053 AK309149 AW449920 AY335937 BC136573
RefSeq transcript (Entrez)NM_024335
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IRX6
Cluster EST : UnigeneHs.369907 [ NCBI ]
CGAP (NCI)Hs.369907
Alternative Splicing GalleryENSG00000159387
Gene ExpressionIRX6 [ NCBI-GEO ]   IRX6 [ EBI - ARRAY_EXPRESS ]   IRX6 [ SEEK ]   IRX6 [ MEM ]
Gene Expression Viewer (FireBrowse)IRX6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79190
GTEX Portal (Tissue expression)IRX6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78412   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78412  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78412
Splice isoforms : SwissVarP78412
PhosPhoSitePlusP78412
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_KN_domain    Iroquois_homeo   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  IRO (SM00548)  
Conserved Domain (NCBI)IRX6
DMDM Disease mutations79190
Blocks (Seattle)IRX6
SuperfamilyP78412
Human Protein AtlasENSG00000159387
Peptide AtlasP78412
HPRD12091
IPIIPI00400792   
Protein Interaction databases
DIP (DOE-UCLA)P78412
IntAct (EBI)P78412
FunCoupENSG00000159387
BioGRIDIRX6
STRING (EMBL)IRX6
ZODIACIRX6
Ontologies - Pathways
QuickGOP78412
Ontology : AmiGOnucleus  regulation of transcription, DNA-templated  sequence-specific DNA binding  
Ontology : EGO-EBInucleus  regulation of transcription, DNA-templated  sequence-specific DNA binding  
NDEx NetworkIRX6
Atlas of Cancer Signalling NetworkIRX6
Wikipedia pathwaysIRX6
Orthology - Evolution
OrthoDB79190
GeneTree (enSembl)ENSG00000159387
Phylogenetic Trees/Animal Genes : TreeFamIRX6
HOVERGENP78412
HOGENOMP78412
Homologs : HomoloGeneIRX6
Homology/Alignments : Family Browser (UCSC)IRX6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIRX6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IRX6
dbVarIRX6
ClinVarIRX6
1000_GenomesIRX6 
Exome Variant ServerIRX6
ExAC (Exome Aggregation Consortium)IRX6 (select the gene name)
Genetic variants : HAPMAP79190
Genomic Variants (DGV)IRX6 [DGVbeta]
DECIPHERIRX6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIRX6 
Mutations
ICGC Data PortalIRX6 
TCGA Data PortalIRX6 
Broad Tumor PortalIRX6
OASIS PortalIRX6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIRX6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIRX6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IRX6
DgiDB (Drug Gene Interaction Database)IRX6
DoCM (Curated mutations)IRX6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IRX6 (select a term)
intoGenIRX6
Cancer3DIRX6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606196   
Orphanet
MedgenIRX6
Genetic Testing Registry IRX6
NextProtP78412 [Medical]
TSGene79190
GENETestsIRX6
Target ValidationIRX6
Huge Navigator IRX6 [HugePedia]
snp3D : Map Gene to Disease79190
BioCentury BCIQIRX6
ClinGenIRX6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79190
Chemical/Pharm GKB GenePA29929
Clinical trialIRX6
Miscellaneous
canSAR (ICR)IRX6 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIRX6
EVEXIRX6
GoPubMedIRX6
iHOPIRX6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:20 CEST 2017

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