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ISCA1 (iron-sulfur cluster assembly 1)

Identity

Alias_namesHBLD2
HESB like domain containing 2
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
Alias_symbol (synonym)MGC4276
ISA1
hIscA
Other alias
HGNC (Hugo) ISCA1
LocusID (NCBI) 81689
Atlas_Id 64667
Location 9q21.33  [Link to chromosome band 9q21]
Location_base_pair Starts at 86264548 and ends at 86282575 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ISCA1   28660
Cards
Entrez_Gene (NCBI)ISCA1  81689  iron-sulfur cluster assembly 1
AliasesHBLD2; ISA1; hIscA
GeneCards (Weizmann)ISCA1
Ensembl hg19 (Hinxton)ENSG00000135070 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135070 [Gene_View]  chr9:86264548-86282575 [Contig_View]  ISCA1 [Vega]
ICGC DataPortalENSG00000135070
TCGA cBioPortalISCA1
AceView (NCBI)ISCA1
Genatlas (Paris)ISCA1
WikiGenes81689
SOURCE (Princeton)ISCA1
Genetics Home Reference (NIH)ISCA1
Genomic and cartography
GoldenPath hg38 (UCSC)ISCA1  -     chr9:86264548-86282575 -  9q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ISCA1  -     9q21.33   [Description]    (hg19-Feb_2009)
EnsemblISCA1 - 9q21.33 [CytoView hg19]  ISCA1 - 9q21.33 [CytoView hg38]
Mapping of homologs : NCBIISCA1 [Mapview hg19]  ISCA1 [Mapview hg38]
OMIM611006   
Gene and transcription
Genbank (Entrez)AA745613 AF038186 AF284752 AI436792 AK055643
RefSeq transcript (Entrez)NM_030940
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ISCA1
Cluster EST : UnigeneHs.449291 [ NCBI ]
CGAP (NCI)Hs.449291
Alternative Splicing GalleryENSG00000135070
Gene ExpressionISCA1 [ NCBI-GEO ]   ISCA1 [ EBI - ARRAY_EXPRESS ]   ISCA1 [ SEEK ]   ISCA1 [ MEM ]
Gene Expression Viewer (FireBrowse)ISCA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81689
GTEX Portal (Tissue expression)ISCA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUE6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUE6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUE6
Splice isoforms : SwissVarQ9BUE6
PhosPhoSitePlusQ9BUE6
Domaine pattern : Prosite (Expaxy)HESB (PS01152)   
Domains : Interpro (EBI)FeS_biogenesis    FeS_cluster_insertion    FeS_cluster_insertion_CS   
Domain families : Pfam (Sanger)Fe-S_biosyn (PF01521)   
Domain families : Pfam (NCBI)pfam01521   
Conserved Domain (NCBI)ISCA1
DMDM Disease mutations81689
Blocks (Seattle)ISCA1
SuperfamilyQ9BUE6
Human Protein AtlasENSG00000135070
Peptide AtlasQ9BUE6
HPRD17091
IPIIPI00939800   IPI00329615   IPI00642289   IPI00640761   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUE6
IntAct (EBI)Q9BUE6
FunCoupENSG00000135070
BioGRIDISCA1
STRING (EMBL)ISCA1
ZODIACISCA1
Ontologies - Pathways
QuickGOQ9BUE6
Ontology : AmiGOstructural molecule activity  mitochondrial matrix  ferrous iron binding  iron-sulfur cluster assembly  2 iron, 2 sulfur cluster binding  protein maturation by iron-sulfur cluster transfer  
Ontology : EGO-EBIstructural molecule activity  mitochondrial matrix  ferrous iron binding  iron-sulfur cluster assembly  2 iron, 2 sulfur cluster binding  protein maturation by iron-sulfur cluster transfer  
NDEx NetworkISCA1
Atlas of Cancer Signalling NetworkISCA1
Wikipedia pathwaysISCA1
Orthology - Evolution
OrthoDB81689
GeneTree (enSembl)ENSG00000135070
Phylogenetic Trees/Animal Genes : TreeFamISCA1
HOVERGENQ9BUE6
HOGENOMQ9BUE6
Homologs : HomoloGeneISCA1
Homology/Alignments : Family Browser (UCSC)ISCA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerISCA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ISCA1
dbVarISCA1
ClinVarISCA1
1000_GenomesISCA1 
Exome Variant ServerISCA1
ExAC (Exome Aggregation Consortium)ISCA1 (select the gene name)
Genetic variants : HAPMAP81689
Genomic Variants (DGV)ISCA1 [DGVbeta]
DECIPHERISCA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisISCA1 
Mutations
ICGC Data PortalISCA1 
TCGA Data PortalISCA1 
Broad Tumor PortalISCA1
OASIS PortalISCA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICISCA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDISCA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ISCA1
DgiDB (Drug Gene Interaction Database)ISCA1
DoCM (Curated mutations)ISCA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ISCA1 (select a term)
intoGenISCA1
Cancer3DISCA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611006   
Orphanet
MedgenISCA1
Genetic Testing Registry ISCA1
NextProtQ9BUE6 [Medical]
TSGene81689
GENETestsISCA1
Target ValidationISCA1
Huge Navigator ISCA1 [HugePedia]
snp3D : Map Gene to Disease81689
BioCentury BCIQISCA1
ClinGenISCA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81689
Chemical/Pharm GKB GenePA162392301
Clinical trialISCA1
Miscellaneous
canSAR (ICR)ISCA1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineISCA1
EVEXISCA1
GoPubMedISCA1
iHOPISCA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:53:41 CEST 2017

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