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ISCA2 (iron-sulfur cluster assembly 2)

Identity

Alias_namesHBLD1
HesB like domain containing 1
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
Alias_symbol (synonym)ISA2
Other aliasMMDS4
c14_5557
HGNC (Hugo) ISCA2
LocusID (NCBI) 122961
Atlas_Id 64668
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 74493720 and ends at 74495568 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ISCA2   19857
Cards
Entrez_Gene (NCBI)ISCA2  122961  iron-sulfur cluster assembly 2
AliasesHBLD1; ISA2; MMDS4; c14_5557
GeneCards (Weizmann)ISCA2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14:74493720-74495568 [Contig_View]  ISCA2 [Vega]
TCGA cBioPortalISCA2
AceView (NCBI)ISCA2
Genatlas (Paris)ISCA2
WikiGenes122961
SOURCE (Princeton)ISCA2
Genetics Home Reference (NIH)ISCA2
Genomic and cartography
GoldenPath hg38 (UCSC)ISCA2  -     chr14:74493720-74495568 +  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ISCA2  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblISCA2 - 14q24.3 [CytoView hg19]  ISCA2 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBIISCA2 [Mapview hg19]  ISCA2 [Mapview hg38]
OMIM615317   616370   
Gene and transcription
Genbank (Entrez)AK290728 BC015771 BC032893 BX114918 BX248252
RefSeq transcript (Entrez)NM_001272007 NM_194279
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ISCA2
Cluster EST : UnigeneHs.291079 [ NCBI ]
CGAP (NCI)Hs.291079
Gene ExpressionISCA2 [ NCBI-GEO ]   ISCA2 [ EBI - ARRAY_EXPRESS ]   ISCA2 [ SEEK ]   ISCA2 [ MEM ]
Gene Expression Viewer (FireBrowse)ISCA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122961
GTEX Portal (Tissue expression)ISCA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86U28   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86U28  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86U28
Splice isoforms : SwissVarQ86U28
PhosPhoSitePlusQ86U28
Domaine pattern : Prosite (Expaxy)HESB (PS01152)   
Domains : Interpro (EBI)FeS_biogenesis    FeS_cluster_insertion    FeS_cluster_insertion_CS   
Domain families : Pfam (Sanger)Fe-S_biosyn (PF01521)   
Domain families : Pfam (NCBI)pfam01521   
Conserved Domain (NCBI)ISCA2
DMDM Disease mutations122961
Blocks (Seattle)ISCA2
SuperfamilyQ86U28
Peptide AtlasQ86U28
HPRD17090
IPIIPI00376195   IPI01026411   IPI01026525   
Protein Interaction databases
DIP (DOE-UCLA)Q86U28
IntAct (EBI)Q86U28
BioGRIDISCA2
STRING (EMBL)ISCA2
ZODIACISCA2
Ontologies - Pathways
QuickGOQ86U28
Ontology : AmiGOstructural molecule activity  iron ion binding  protein binding  mitochondrion  iron-sulfur cluster assembly  2 iron, 2 sulfur cluster binding  4 iron, 4 sulfur cluster binding  protein maturation  protein maturation by iron-sulfur cluster transfer  
Ontology : EGO-EBIstructural molecule activity  iron ion binding  protein binding  mitochondrion  iron-sulfur cluster assembly  2 iron, 2 sulfur cluster binding  4 iron, 4 sulfur cluster binding  protein maturation  protein maturation by iron-sulfur cluster transfer  
NDEx NetworkISCA2
Atlas of Cancer Signalling NetworkISCA2
Wikipedia pathwaysISCA2
Orthology - Evolution
OrthoDB122961
Phylogenetic Trees/Animal Genes : TreeFamISCA2
HOVERGENQ86U28
HOGENOMQ86U28
Homologs : HomoloGeneISCA2
Homology/Alignments : Family Browser (UCSC)ISCA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerISCA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ISCA2
dbVarISCA2
ClinVarISCA2
1000_GenomesISCA2 
Exome Variant ServerISCA2
ExAC (Exome Aggregation Consortium)ISCA2 (select the gene name)
Genetic variants : HAPMAP122961
Genomic Variants (DGV)ISCA2 [DGVbeta]
DECIPHERISCA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisISCA2 
Mutations
ICGC Data PortalISCA2 
TCGA Data PortalISCA2 
Broad Tumor PortalISCA2
OASIS PortalISCA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICISCA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDISCA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ISCA2
DgiDB (Drug Gene Interaction Database)ISCA2
DoCM (Curated mutations)ISCA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ISCA2 (select a term)
intoGenISCA2
Cancer3DISCA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615317    616370   
Orphanet23727   
MedgenISCA2
Genetic Testing Registry ISCA2
NextProtQ86U28 [Medical]
TSGene122961
GENETestsISCA2
Target ValidationISCA2
Huge Navigator ISCA2 [HugePedia]
snp3D : Map Gene to Disease122961
BioCentury BCIQISCA2
ClinGenISCA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD122961
Chemical/Pharm GKB GenePA162392315
Clinical trialISCA2
Miscellaneous
canSAR (ICR)ISCA2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineISCA2
EVEXISCA2
GoPubMedISCA2
iHOPISCA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:53:42 CEST 2017

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