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ISLR (immunoglobulin superfamily containing leucine-rich repeat)

Identity

Alias_symbol (synonym)HsT17563
Other alias
HGNC (Hugo) ISLR
LocusID (NCBI) 3671
Atlas_Id 64671
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 74466087 and ends at 74469212 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CHST15 (10q26.13) / ISLR (15q24.1)FAM219A (9p13.3) / ISLR (15q24.1)ISLR (15q24.1) / FAM219A (9p13.3)
PLEKHA2 (8p11.22) / ISLR (15q24.1)SPG11 (15q21.1) / ISLR (15q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ISLR   6133
Cards
Entrez_Gene (NCBI)ISLR  3671  immunoglobulin superfamily containing leucine-rich repeat
AliasesHsT17563
GeneCards (Weizmann)ISLR
Ensembl hg19 (Hinxton)ENSG00000129009 [Gene_View]  chr15:74466087-74469212 [Contig_View]  ISLR [Vega]
Ensembl hg38 (Hinxton)ENSG00000129009 [Gene_View]  chr15:74466087-74469212 [Contig_View]  ISLR [Vega]
ICGC DataPortalENSG00000129009
TCGA cBioPortalISLR
AceView (NCBI)ISLR
Genatlas (Paris)ISLR
WikiGenes3671
SOURCE (Princeton)ISLR
Genetics Home Reference (NIH)ISLR
Genomic and cartography
GoldenPath hg19 (UCSC)ISLR  -     chr15:74466087-74469212 +  15q24.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ISLR  -     15q24.1   [Description]    (hg38-Dec_2013)
EnsemblISLR - 15q24.1 [CytoView hg19]  ISLR - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBIISLR [Mapview hg19]  ISLR [Mapview hg38]
OMIM602059   
Gene and transcription
Genbank (Entrez)AB003184 AB024536 AK000817 AK074668 AK223267
RefSeq transcript (Entrez)NM_005545 NM_201526
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)ISLR
Cluster EST : UnigeneHs.745166 [ NCBI ]
CGAP (NCI)Hs.745166
Alternative Splicing GalleryENSG00000129009
Gene ExpressionISLR [ NCBI-GEO ]   ISLR [ EBI - ARRAY_EXPRESS ]   ISLR [ SEEK ]   ISLR [ MEM ]
Gene Expression Viewer (FireBrowse)ISLR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3671
GTEX Portal (Tissue expression)ISLR
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14498   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14498  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14498
Splice isoforms : SwissVarO14498
PhosPhoSitePlusO14498
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam07679    pfam13855   
Domain families : Smart (EMBL)IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)ISLR
DMDM Disease mutations3671
Blocks (Seattle)ISLR
SuperfamilyO14498
Human Protein AtlasENSG00000129009
Peptide AtlasO14498
HPRD03636
IPIIPI00023648   
Protein Interaction databases
DIP (DOE-UCLA)O14498
IntAct (EBI)O14498
FunCoupENSG00000129009
BioGRIDISLR
STRING (EMBL)ISLR
ZODIACISLR
Ontologies - Pathways
QuickGOO14498
Ontology : AmiGOcell adhesion  extracellular exosome  
Ontology : EGO-EBIcell adhesion  extracellular exosome  
NDEx NetworkISLR
Atlas of Cancer Signalling NetworkISLR
Wikipedia pathwaysISLR
Orthology - Evolution
OrthoDB3671
GeneTree (enSembl)ENSG00000129009
Phylogenetic Trees/Animal Genes : TreeFamISLR
HOVERGENO14498
HOGENOMO14498
Homologs : HomoloGeneISLR
Homology/Alignments : Family Browser (UCSC)ISLR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerISLR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ISLR
dbVarISLR
ClinVarISLR
1000_GenomesISLR 
Exome Variant ServerISLR
ExAC (Exome Aggregation Consortium)ISLR (select the gene name)
Genetic variants : HAPMAP3671
Genomic Variants (DGV)ISLR [DGVbeta]
DECIPHER (Syndromes)15:74466087-74469212  ENSG00000129009
CONAN: Copy Number AnalysisISLR 
Mutations
ICGC Data PortalISLR 
TCGA Data PortalISLR 
Broad Tumor PortalISLR
OASIS PortalISLR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICISLR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDISLR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ISLR
DgiDB (Drug Gene Interaction Database)ISLR
DoCM (Curated mutations)ISLR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ISLR (select a term)
intoGenISLR
Cancer3DISLR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602059   
Orphanet
MedgenISLR
Genetic Testing Registry ISLR
NextProtO14498 [Medical]
TSGene3671
GENETestsISLR
Huge Navigator ISLR [HugePedia]
snp3D : Map Gene to Disease3671
BioCentury BCIQISLR
ClinGenISLR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3671
Chemical/Pharm GKB GenePA29933
Clinical trialISLR
Miscellaneous
canSAR (ICR)ISLR (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineISLR
EVEXISLR
GoPubMedISLR
iHOPISLR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:09:03 CET 2017

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