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ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2)

Identity

Alias_symbol (synonym)KIAA1465
Other aliasLINX
HGNC (Hugo) ISLR2
LocusID (NCBI) 57611
Atlas_Id 64672
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 74129374 and ends at 74136802 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ISLR2 (15q24.1) / FRMPD4 (Xp22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ISLR2   29286
Cards
Entrez_Gene (NCBI)ISLR2  57611  immunoglobulin superfamily containing leucine rich repeat 2
AliasesLINX
GeneCards (Weizmann)ISLR2
Ensembl hg19 (Hinxton)ENSG00000167178 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167178 [Gene_View]  chr15:74129374-74136802 [Contig_View]  ISLR2 [Vega]
ICGC DataPortalENSG00000167178
TCGA cBioPortalISLR2
AceView (NCBI)ISLR2
Genatlas (Paris)ISLR2
WikiGenes57611
SOURCE (Princeton)ISLR2
Genetics Home Reference (NIH)ISLR2
Genomic and cartography
GoldenPath hg38 (UCSC)ISLR2  -     chr15:74129374-74136802 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ISLR2  -     15q24.1   [Description]    (hg19-Feb_2009)
EnsemblISLR2 - 15q24.1 [CytoView hg19]  ISLR2 - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBIISLR2 [Mapview hg19]  ISLR2 [Mapview hg38]
OMIM614179   
Gene and transcription
Genbank (Entrez)AB040898 AK092297 AK092302 AK096602 AK290467
RefSeq transcript (Entrez)NM_001130136 NM_001130137 NM_001130138 NM_020851
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ISLR2
Cluster EST : UnigeneHs.254775 [ NCBI ]
CGAP (NCI)Hs.254775
Alternative Splicing GalleryENSG00000167178
Gene ExpressionISLR2 [ NCBI-GEO ]   ISLR2 [ EBI - ARRAY_EXPRESS ]   ISLR2 [ SEEK ]   ISLR2 [ MEM ]
Gene Expression Viewer (FireBrowse)ISLR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57611
GTEX Portal (Tissue expression)ISLR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXK2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXK2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXK2
Splice isoforms : SwissVarQ6UXK2
PhosPhoSitePlusQ6UXK2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)ISLR2
DMDM Disease mutations57611
Blocks (Seattle)ISLR2
SuperfamilyQ6UXK2
Human Protein AtlasENSG00000167178
Peptide AtlasQ6UXK2
HPRD13865
IPIIPI00479654   IPI00744941   
Protein Interaction databases
DIP (DOE-UCLA)Q6UXK2
IntAct (EBI)Q6UXK2
FunCoupENSG00000167178
BioGRIDISLR2
STRING (EMBL)ISLR2
ZODIACISLR2
Ontologies - Pathways
QuickGOQ6UXK2
Ontology : AmiGOplasma membrane  cell surface  cell surface  integral component of membrane  positive regulation of axon extension  positive regulation of axon extension  
Ontology : EGO-EBIplasma membrane  cell surface  cell surface  integral component of membrane  positive regulation of axon extension  positive regulation of axon extension  
NDEx NetworkISLR2
Atlas of Cancer Signalling NetworkISLR2
Wikipedia pathwaysISLR2
Orthology - Evolution
OrthoDB57611
GeneTree (enSembl)ENSG00000167178
Phylogenetic Trees/Animal Genes : TreeFamISLR2
HOVERGENQ6UXK2
HOGENOMQ6UXK2
Homologs : HomoloGeneISLR2
Homology/Alignments : Family Browser (UCSC)ISLR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerISLR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ISLR2
dbVarISLR2
ClinVarISLR2
1000_GenomesISLR2 
Exome Variant ServerISLR2
ExAC (Exome Aggregation Consortium)ISLR2 (select the gene name)
Genetic variants : HAPMAP57611
Genomic Variants (DGV)ISLR2 [DGVbeta]
DECIPHERISLR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisISLR2 
Mutations
ICGC Data PortalISLR2 
TCGA Data PortalISLR2 
Broad Tumor PortalISLR2
OASIS PortalISLR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICISLR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDISLR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ISLR2
DgiDB (Drug Gene Interaction Database)ISLR2
DoCM (Curated mutations)ISLR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ISLR2 (select a term)
intoGenISLR2
Cancer3DISLR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614179   
Orphanet
MedgenISLR2
Genetic Testing Registry ISLR2
NextProtQ6UXK2 [Medical]
TSGene57611
GENETestsISLR2
Target ValidationISLR2
Huge Navigator ISLR2 [HugePedia]
snp3D : Map Gene to Disease57611
BioCentury BCIQISLR2
ClinGenISLR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57611
Chemical/Pharm GKB GenePA143485505
Clinical trialISLR2
Miscellaneous
canSAR (ICR)ISLR2 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineISLR2
EVEXISLR2
GoPubMedISLR2
iHOPISLR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:21 CEST 2017

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