ISYNA1 (inositol-3-phosphate synthase 1)

2003-12-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
INO1,INOS,IPS,IPS
FUSION GENES

Other Information

Locus ID:

NCBI: 51477
MIM: 611670
HGNC: 29821
Ensembl: ENSG00000105655

Variants:

dbSNP: 51477
ClinVar: 51477
TCGA: ENSG00000105655
COSMIC: ISYNA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105655ENST00000338128Q9NPH2
ENSG00000105655ENST00000338128A0A140VK73
ENSG00000105655ENST00000457269Q9NPH2
ENSG00000105655ENST00000577820J3QKW9
ENSG00000105655ENST00000578352J3KRH4
ENSG00000105655ENST00000578963Q9NPH2
ENSG00000105655ENST00000581672J3QS51
ENSG00000105655ENST00000581800J3QLD7
ENSG00000105655ENST00000582770J3QRH1
ENSG00000105655ENST00000582811J3QKW9
ENSG00000105655ENST00000583534J3QRY0

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
Inositol phosphate metabolismKEGGko00562
Inositol phosphate metabolismKEGGhsa00562
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Inositol phosphate metabolismREACTOMER-HSA-1483249
Synthesis of IP2, IP, and Ins in the cytosolREACTOMER-HSA-1855183

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
239027602013Phosphorylation regulates myo-inositol-3-phosphate synthase: a novel regulatory mechanism of inositol biosynthesis.17
154647312004E2F1 regulation of the human myo-inositol 1-phosphate synthase (ISYNA1) gene promoter.5
227070962012L-myo-inositol-1-phosphate synthase expressed in developing organ: isolation and characterisation of the enzyme from human fetal liver.1
308616502019[Clinicopathological significance of ISYNA1 expression in pancreatic ductal adenocarcinoma].0
314954922019ISYNA1 is overexpressed in bladder carcinoma and regulates cell proliferation and apoptosis.0

Citation

Dessen P

ISYNA1 (inositol-3-phosphate synthase 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40998/isyna1