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ITGA1 (integrin, alpha 1)

Identity

Other namesCD49a
VLA1
HGNC (Hugo) ITGA1
LocusID (NCBI) 3672
Location 5q11.2
Location_base_pair Starts at 52084136 and ends at 52249485 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ITGA1   6134
Entrez_Gene (NCBI)ITGA1  3672  integrin, alpha 1
Cards
GeneCards (Weizmann)ITGA1
Ensembl (Hinxton) [Gene_View]  chr5:52084136-52249485 [Contig_View]  ITGA1 [Vega]
AceView (NCBI)ITGA1
Genatlas (Paris)ITGA1
SOURCE (Stanford)NM_181501
Genomic and cartography
GoldenPath (UCSC)ITGA1  -  5q11.2   chr5:52084136-52249485 +  5q11.2   [Description]    (hg19-Feb_2009)
EnsemblITGA1 - 5q11.2 [CytoView]
Mapping of homologs : NCBIITGA1 [Mapview]
OMIM192968   
Gene and transcription
Genbank (Entrez)AK300423 BC050277 BC137121 BC137122 X68742
RefSeq transcript (SRS)NM_181501
RefSeq transcript (Entrez)NM_181501
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NT_006713 NW_001838934 NW_004078023
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NT_006713 NW_001838934 NW_004078023
Consensus coding sequences : CCDS (NCBI)ITGA1
Cluster EST : UnigeneHs.644352 [ SRS ] Hs.644352 [ NCBI ]
CGAP (NCI)Hs.644352
Alternative Splicing : Fast-db (Paris)GSHG0023924
Gene ExpressionITGA1 [ NCBI-GEO ]   ITGA1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56199 (SRS) P56199 (Uniprot)
NextProtP56199
With graphics : InterProP56199
Splice isoforms : SwissVarP56199(Swissvar)
Domaine pattern : Prosite (SRS)FG_GAP (PS51470)    INTEGRIN_ALPHA (PS00242)    VWFA (PS50234)   
Domaine pattern : Prosite (Expaxy)FG_GAP (PS51470)    INTEGRIN_ALPHA (PS00242)    VWFA (PS50234)   
Domains : Interpro (SRS)FG-GAP    Int_alpha_beta-p    Integrin_alpha    Integrin_alpha-2    Integrin_alpha_C_CS    VWF_A   
Domains : Interpro (EBI)FG-GAP    Int_alpha_beta-p    Integrin_alpha    Integrin_alpha-2    Integrin_alpha_C_CS    VWF_A   
Related proteins : CluSTrP56199
Domain families : Pfam (SRS)FG-GAP (PF01839)    Integrin_alpha2 (PF08441)    VWA (PF00092)   
Domain families : Pfam (Sanger)FG-GAP (PF01839)    Integrin_alpha2 (PF08441)    VWA (PF00092)   
Domain families : Pfam (NCBI)pfam01839    pfam08441    pfam00092   
Domain families : Smart (EMBL)Int_alpha (SM00191)  VWA (SM00327)  
DMDM3672
Blocks (Seattle)P56199
PDB (SRS)1PT6    1QC5    1QCY    2L8S    4A0Q   
PDB (PDBSum)1PT6    1QC5    1QCY    2L8S    4A0Q   
PDB (IMB)1PT6    1QC5    1QCY    2L8S    4A0Q   
PDB (RSDB)1PT6    1QC5    1QCY    2L8S    4A0Q   
HPRD01892
IPIIPI00743104   
Protein Interaction databases
DIP (DOE-UCLA)P56199
IntAct (EBI)P56199
REACTOMEITGA1
Protein Interaction Database3672
BioGRIDITGA1
InParanoidP56199
Interologous Interaction database P56199
IntegromeDBITGA1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ITGA1
SNP (GeneSNP Utah)ITGA1
SNP : HGBaseITGA1
Genetic variants : HAPMAPITGA1
Somatic Mutations in Cancer : COSMICITGA1 
CONAN: Copy Number AnalysisITGA1 
Mutations and Diseases : HGMDITGA1
OMIM192968   
GENETests192968   
Disease Genetic AssociationITGA1
Huge Navigator ITGA1 [HugePedia]  ITGA1 [HugeCancerGEM]
Genomic VariantsITGA1  ITGA1 [DGVbeta]
ClinVarITGA1
snp3D : Map Gene to Disease3672
General knowledge
Homologs : HomoloGeneITGA1
Homology/Alignments : Family Browser (UCSC)ITGA1
Phylogenetic Trees/Animal Genes : TreeFamITGA1
Chemical/Protein Interactions : CTD3672
Chemical/Pharm GKB GenePA29935
Clinical trialITGA1
Ontology : AmiGOactivation of MAPK activity  acrosomal vesicle  integrin binding  protein binding  collagen binding  plasma membrane  muscle contraction  cell-matrix adhesion  integrin-mediated signaling pathway  axon guidance  integrin complex  external side of plasma membrane  neutrophil chemotaxis  vasodilation  neuron projection  perikaryon  positive regulation of neuron apoptotic process  membrane raft  cellular extravasation  basal part of cell  metal ion binding  protein heterodimerization activity  
Ontology : EGO-EBIactivation of MAPK activity  acrosomal vesicle  integrin binding  protein binding  collagen binding  plasma membrane  muscle contraction  cell-matrix adhesion  integrin-mediated signaling pathway  axon guidance  integrin complex  external side of plasma membrane  neutrophil chemotaxis  vasodilation  neuron projection  perikaryon  positive regulation of neuron apoptotic process  membrane raft  cellular extravasation  basal part of cell  metal ion binding  protein heterodimerization activity  
Other databases
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
PubGeneITGA1
iHOPITGA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:43:47 CEST 2013
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