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ITGA10 (integrin subunit alpha 10)

Identity

Alias_namesintegrin
Other aliasPRO827
HGNC (Hugo) ITGA10
LocusID (NCBI) 8515
Atlas_Id 41000
Location 1q21.1  [Link to chromosome band 1q21]
Location_base_pair Starts at 145891208 and ends at 145910189 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITGA10 (1q21.1) / MSL1 (17q21.1)ITGA10 (1q21.1) / NTN1 (17p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ITGA10   6135
Cards
Entrez_Gene (NCBI)ITGA10  8515  integrin subunit alpha 10
AliasesPRO827
GeneCards (Weizmann)ITGA10
Ensembl hg19 (Hinxton)ENSG00000143127 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143127 [Gene_View]  chr1:145891208-145910189 [Contig_View]  ITGA10 [Vega]
ICGC DataPortalENSG00000143127
TCGA cBioPortalITGA10
AceView (NCBI)ITGA10
Genatlas (Paris)ITGA10
WikiGenes8515
SOURCE (Princeton)ITGA10
Genetics Home Reference (NIH)ITGA10
Genomic and cartography
GoldenPath hg38 (UCSC)ITGA10  -     chr1:145891208-145910189 -  1q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ITGA10  -     1q21.1   [Description]    (hg19-Feb_2009)
EnsemblITGA10 - 1q21.1 [CytoView hg19]  ITGA10 - 1q21.1 [CytoView hg38]
Mapping of homologs : NCBIITGA10 [Mapview hg19]  ITGA10 [Mapview hg38]
OMIM604042   
Gene and transcription
Genbank (Entrez)AF074015 AF112345 AK304155 AK304183 AK314255
RefSeq transcript (Entrez)NM_001303040 NM_001303041 NM_003637
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ITGA10
Cluster EST : UnigeneHs.158237 [ NCBI ]
CGAP (NCI)Hs.158237
Alternative Splicing GalleryENSG00000143127
Gene ExpressionITGA10 [ NCBI-GEO ]   ITGA10 [ EBI - ARRAY_EXPRESS ]   ITGA10 [ SEEK ]   ITGA10 [ MEM ]
Gene Expression Viewer (FireBrowse)ITGA10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8515
GTEX Portal (Tissue expression)ITGA10
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75578   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75578  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75578
Splice isoforms : SwissVarO75578
PhosPhoSitePlusO75578
Domaine pattern : Prosite (Expaxy)FG_GAP (PS51470)    VWFA (PS50234)   
Domains : Interpro (EBI)FG-GAP    Int_alpha_beta-p    Integrin_alpha    Integrin_alpha-2    Integrin_dom    VWF_A   
Domain families : Pfam (Sanger)FG-GAP (PF01839)    Integrin_alpha2 (PF08441)    VWA (PF00092)   
Domain families : Pfam (NCBI)pfam01839    pfam08441    pfam00092   
Domain families : Smart (EMBL)Int_alpha (SM00191)  VWA (SM00327)  
Conserved Domain (NCBI)ITGA10
DMDM Disease mutations8515
Blocks (Seattle)ITGA10
SuperfamilyO75578
Human Protein AtlasENSG00000143127
Peptide AtlasO75578
HPRD04952
IPIIPI00026165   IPI00554717   IPI01015243   IPI01010343   IPI01014801   
Protein Interaction databases
DIP (DOE-UCLA)O75578
IntAct (EBI)O75578
FunCoupENSG00000143127
BioGRIDITGA10
STRING (EMBL)ITGA10
ZODIACITGA10
Ontologies - Pathways
QuickGOO75578
Ontology : AmiGOcollagen binding  plasma membrane  cell-matrix adhesion  integrin-mediated signaling pathway  integrin complex  extracellular matrix organization  integrin alpha10-beta1 complex  metal ion binding  collagen binding involved in cell-matrix adhesion  
Ontology : EGO-EBIcollagen binding  plAsma }eíbrane  cell-matrix adhesion  integrin-mediated signaling pathway  integrin complex  extracellular matrix organization  integrin alpha10-beta1 complex  metal ion binding  collagen binding involved in cell-matrix adhesion  
Pathways : KEGG   
NDEx NetworkITGA10
Atlas of Cancer Signalling NetworkITGA10
Wikipedia pathwaysITGA10
Orthology - Evolution
OrthoDB8515
GeneTree (enSembl)ENSG00000143127
Phylogenetic Trees/Animal Genes : TreeFamITGA10
HOVERGENO75578
HOGENOMO75578
Homologs : HomoloGeneITGA10
Homology/Alignments : Family Browser (UCSC)ITGA10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerITGA10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ITGA10
dbVarITGA10
ClinVarITGA10
1000_GenomesITGA10 
Exome Variant ServerITGA10
ExAC (Exome Aggregation Consortium)ITGA10 (select the gene name)
Genetic variants : HAPMAP8515
Genomic Variants (DGV)ITGA10 [DGVbeta]
DECIPHERITGA10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisITGA10 
Mutations
ICGC Data PortalITGA10 
TCGA Data PortalITGA10 
Broad Tumor PortalITGA10
OASIS PortalITGA10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICITGA10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDITGA10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ITGA10
DgiDB (Drug Gene Interaction Database)ITGA10
DoCM (Curated mutations)ITGA10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ITGA10 (select a term)
intoGenITGA10
Cancer3DITGA10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604042   
Orphanet
MedgenITGA10
Genetic Testing Registry ITGA10
NextProtO75578 [Medical]
TSGene8515
GENETestsITGA10
Target ValidationITGA10
Huge Navigator ITGA10 [HugePedia]
snp3D : Map Gene to Disease8515
BioCentury BCIQITGA10
ClinGenITGA10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8515
Chemical/Pharm GKB GenePA29936
Clinical trialITGA10
Miscellaneous
canSAR (ICR)ITGA10 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineITGA10
EVEXITGA10
GoPubMedITGA10
iHOPITGA10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:56:36 CEST 2017

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