ITGA8 (integrin, alpha 8)

Identity

Other names	-
HGNC	ITGA8
Location	10p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ITGA8   6144
Entrez_Gene	ITGA8  8516  integrin, alpha 8
	Cards
GeneCards	ITGA8
Ensembl	ITGA8 [Search_View]   ENSG00000077943 [Gene_View]
Genatlas	ITGA8
GeneLynx	ITGA8
eGenome	ITGA8
euGene	8516
	Genomic and cartography
GoldenPath	ITGA8  -  10p13   chr10:15599094-15801776 -  10p13   [Description]    (hg18-March_2006)
Ensembl	ITGA8 - 10p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ITGA8
	Gene and transcription
Genbank	AK297740 [ ENTREZ ]
Genbank	AK308240 [ ENTREZ ]
Genbank	BC148352 [ ENTREZ ]
Genbank	L36531 [ ENTREZ ]
RefSeq	NM_003638 [ SRS ]    NM_003638 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_077569 [ SRS ]    NT_077569 [ ENTREZ ]
RefSeq	NW_001837931 [ SRS ]    NW_001837931 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
AceView	ITGA8 AceView - NCBI
Unigene	Hs.171311 [ SRS ]    Hs.171311 [ NCBI ]     HS171311 [ spliceNest ]
Fast-db	3793 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P53708 [ SRS]    P53708 [ EXPASY ]     P53708 [ INTERPRO ]     P53708 [ UNIPROT ]
Prosite	PS00242 INTEGRIN_ALPHA [ SRS ]    PS00242 INTEGRIN_ALPHA [ Expasy ]
Interpro	IPR013517 FG-GAP [ SRS ]    IPR013517 FG-GAP [ EBI ]
Interpro	IPR013519 Int_alpha_beta-p [ SRS ]    IPR013519 Int_alpha_beta-p [ EBI ]
Interpro	IPR000413 Integrin_alpha [ SRS ]    IPR000413 Integrin_alpha [ EBI ]
Interpro	IPR013649 Integrin_alpha-2 [ SRS ]    IPR013649 Integrin_alpha-2 [ EBI ]
Interpro	IPR013513 Integrin_alpha_C [ SRS ]    IPR013513 Integrin_alpha_C [ EBI ]
CluSTr	P53708
Pfam	PF01839 FG-GAP [ SRS ]    PF01839 FG-GAP [ Sanger ]    pfam01839 [ NCBI-CDD ]
Pfam	PF00357 Integrin_alpha [ SRS ]    PF00357 Integrin_alpha [ Sanger ]    pfam00357 [ NCBI-CDD ]
Pfam	PF08441 Integrin_alpha2 [ SRS ]    PF08441 Integrin_alpha2 [ Sanger ]    pfam08441 [ NCBI-CDD ]
Smart	SM00191 Int_alpha [EMBL]
Blocks	P53708
HPRD	10361
	Protein Interaction databases
DIP	P53708
IntAct	P53708
	Polymorphism : SNP, mutations, diseases
OMIM	604063    [ map ]
GENECLINICS	604063
SNP	ITGA8 [dbSNP-NCBI]
SNP	NM_003638 [SNP-NCI]
SNP	ITGA8 [GeneSNPs - Utah]  ITGA8] [HGBASE - SRS]
HAPMAP	ITGA8 [HAPMAP]
COSMIC	ITGA8 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ITGA8
	General knowledge
Family Browser	ITGA8 [UCSC Family Browser]
SOURCE	NM_003638
SMD	Hs.171311
SAGE	Hs.171311
GO	metanephros development [Amigo]  metanephros development
GO	receptor activity [Amigo]  receptor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	cell-matrix adhesion [Amigo]  cell-matrix adhesion
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	nervous system development [Amigo]  nervous system development
GO	memory [Amigo]  memory
GO	integrin complex [Amigo]  integrin complex
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	cell-cell adhesion [Amigo]  cell-cell adhesion
GO	cell projection organization and biogenesis [Amigo]  cell projection organization and biogenesis
GO	cell differentiation [Amigo]  cell differentiation
GO	extracellular matrix organization and biogenesis [Amigo]  extracellular matrix organization and biogenesis
GO	positive regulation of transforming growth factor beta receptor signaling pathway [Amigo]  positive regulation of transforming growth factor beta receptor signaling pathway
GO	inner ear morphogenesis [Amigo]  inner ear morphogenesis
GO	apical part of cell [Amigo]  apical part of cell
KEGG	Focal adhesion
KEGG	ECM-receptor interaction
KEGG	Cell adhesion molecules (CAMs)
KEGG	Regulation of actin cytoskeleton
PubGene	ITGA8
TreeFam	ITGA8
CTD	8516 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ITGA8 Related clones (RZPD - Berlin)
	PubMed
PubMed	14 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:16:33 2008