ITGB1BP1 (integrin subunit beta 1 binding protein 1)

2007-04-01  

Identity

HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
ICAP-1A,ICAP-1B,ICAP-1alpha,ICAP1,ICAP1A,ICAP1B
FUSION GENES

Other Information

Locus ID:

NCBI: 9270
MIM: 607153
HGNC: 23927
Ensembl: ENSG00000119185

Variants:

dbSNP: 9270
ClinVar: 9270
TCGA: ENSG00000119185
COSMIC: ITGB1BP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119185ENST00000238091O14713
ENSG00000119185ENST00000355346O14713
ENSG00000119185ENST00000359712A8MPU2
ENSG00000119185ENST00000360635O14713
ENSG00000119185ENST00000456913A8MPU2
ENSG00000119185ENST00000460001C9J6Y2
ENSG00000119185ENST00000464228F8WF20
ENSG00000119185ENST00000467606C9JZ07
ENSG00000119185ENST00000483795G3V1A3
ENSG00000119185ENST00000484735C9J0J6
ENSG00000119185ENST00000488451O14713
ENSG00000119185ENST00000492079C9JBU8
ENSG00000119185ENST00000494563C9J5T5
ENSG00000119185ENST00000497105C9IZZ8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

References

Pubmed IDYearTitleCitations
151662382004Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway.121
118541712002KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis.63
233175062013Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation.40
206163132010Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis.25
227363992012Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.25
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.22
188129692008Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation.19
117419082002Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.16
157032142005Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.13
171333552007MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha.8

Citation

Dessen P

ITGB1BP1 (integrin subunit beta 1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47086/itgb1bp1