ITGB8 (integrin, beta 8)

Identity

Other names	-
HGNC	ITGB8
Location	7p15.3
Location_base_pair	Starts at 20337250 and ends at 20421907 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ITGB8   6163
Entrez_Gene	ITGB8  3696  integrin, beta 8
	Cards
GeneCards	ITGB8
Ensembl	ITGB8 [Search_View]   ENSG00000105855 [Gene_View]
Genatlas	ITGB8
GeneLynx	ITGB8
eGenome	ITGB8
euGene	3696
	Genomic and cartography
GoldenPath	ITGB8  -  7p15.3   chr7:20337250-20421907 +  7p15.3   [Description]    (hg18-March_2006)
Ensembl	ITGB8 - 7p15.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ITGB8
	Gene and transcription
Genbank	AB209429 [ ENTREZ ]
Genbank	AW516961 [ ENTREZ ]
Genbank	BC002630 [ ENTREZ ]
Genbank	BC042028 [ ENTREZ ]
Genbank	BI861225 [ ENTREZ ]
RefSeq	NM_002214 [ SRS ]    NM_002214 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001839003 [ SRS ]    NW_001839003 [ ENTREZ ]
RefSeq	NW_923240 [ SRS ]    NW_923240 [ ENTREZ ]
AceView	ITGB8 AceView - NCBI
Unigene	Hs.592171 [ SRS ]    Hs.592171 [ NCBI ]     HS592171 [ spliceNest ]
Fast-db	2409 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P26012 [ SRS]    P26012 [ EXPASY ]     P26012 [ INTERPRO ]     P26012 [ UNIPROT ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS00243 INTEGRIN_BETA [ SRS ]    PS00243 INTEGRIN_BETA [ Expasy ]
Prosite	PS50234 VWFA [ SRS ]    PS50234 VWFA [ Expasy ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR013111 EGF_extracell [ SRS ]    IPR013111 EGF_extracell [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR015812 Integrin_bsu [ SRS ]    IPR015812 Integrin_bsu [ EBI ]
Interpro	IPR015442 Integrin_bsu-8-like_C [ SRS ]    IPR015442 Integrin_bsu-8-like_C [ EBI ]
Interpro	IPR001169 Integrin_bsu_C [ SRS ]    IPR001169 Integrin_bsu_C [ EBI ]
Interpro	IPR002369 Integrin_bsu_N [ SRS ]    IPR002369 Integrin_bsu_N [ EBI ]
Interpro	IPR012012 Integrin_bsu_subgr [ SRS ]    IPR012012 Integrin_bsu_subgr [ EBI ]
Interpro	IPR003659 Plexin-like [ SRS ]    IPR003659 Plexin-like [ EBI ]
Interpro	IPR002035 VWF_A [ SRS ]    IPR002035 VWF_A [ EBI ]
CluSTr	P26012
Pfam	PF07974 EGF_2 [ SRS ]    PF07974 EGF_2 [ Sanger ]    pfam07974 [ NCBI-CDD ]
Pfam	PF00362 Integrin_beta [ SRS ]    PF00362 Integrin_beta [ Sanger ]    pfam00362 [ NCBI-CDD ]
Smart	SM00181 EGF [EMBL]
Smart	SM00187 INB [EMBL]
Smart	SM00423 PSI [EMBL]
Smart	SM00327 VWA [EMBL]
Blocks	P26012
HPRD	05001
	Protein Interaction databases
DIP	P26012
IntAct	P26012
	Polymorphism : SNP, mutations, diseases
OMIM	604160    [ map ]
GENECLINICS	604160
SNP	ITGB8 [dbSNP-NCBI]
SNP	NM_002214 [SNP-NCI]
SNP	ITGB8 [GeneSNPs - Utah]  ITGB8] [HGBASE - SRS]
HAPMAP	ITGB8 [HAPMAP]
COSMIC	ITGB8 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ITGB8
	General knowledge
Family Browser	ITGB8 [UCSC Family Browser]
SOURCE	NM_002214
SMD	Hs.592171
SAGE	Hs.592171
GO	ganglioside metabolic process [Amigo]  ganglioside metabolic process
GO	receptor activity [Amigo]  receptor activity
GO	binding [Amigo]  binding
GO	protein binding [Amigo]  protein binding
GO	cell adhesion [Amigo]  cell adhesion
GO	cell adhesion [Amigo]  cell adhesion
GO	cell-matrix adhesion [Amigo]  cell-matrix adhesion
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	integrin complex [Amigo]  integrin complex
GO	integrin complex [Amigo]  integrin complex
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
KEGG	Focal adhesion
KEGG	ECM-receptor interaction
KEGG	Cell adhesion molecules (CAMs)
KEGG	Regulation of actin cytoskeleton
PubGene	ITGB8
TreeFam	ITGB8
CTD	3696 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ITGB8 Related clones (RZPD - Berlin)
	PubMed
PubMed	14 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:47:09 2008