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ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2)

Identity

Alias_namesinter-alpha (globulin) inhibitor
Alias_symbol (synonym)H2P
Other aliasSHAP
HGNC (Hugo) ITIH2
LocusID (NCBI) 3698
Atlas_Id 50300
Location 10p14  [Link to chromosome band 10p14]
Location_base_pair Starts at 7703273 and ends at 7749520 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ITIH2   6167
Cards
Entrez_Gene (NCBI)ITIH2  3698  inter-alpha-trypsin inhibitor heavy chain 2
AliasesH2P; SHAP
GeneCards (Weizmann)ITIH2
Ensembl hg19 (Hinxton)ENSG00000151655 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151655 [Gene_View]  chr10:7703273-7749520 [Contig_View]  ITIH2 [Vega]
ICGC DataPortalENSG00000151655
TCGA cBioPortalITIH2
AceView (NCBI)ITIH2
Genatlas (Paris)ITIH2
WikiGenes3698
SOURCE (Princeton)ITIH2
Genetics Home Reference (NIH)ITIH2
Genomic and cartography
GoldenPath hg38 (UCSC)ITIH2  -     chr10:7703273-7749520 +  10p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ITIH2  -     10p14   [Description]    (hg19-Feb_2009)
EnsemblITIH2 - 10p14 [CytoView hg19]  ITIH2 - 10p14 [CytoView hg38]
Mapping of homologs : NCBIITIH2 [Mapview hg19]  ITIH2 [Mapview hg38]
OMIM146640   
Gene and transcription
Genbank (Entrez)AA406494 AK225277 AK225329 AK291379 AK297334
RefSeq transcript (Entrez)NM_002216
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ITIH2
Cluster EST : UnigeneHs.75285 [ NCBI ]
CGAP (NCI)Hs.75285
Alternative Splicing GalleryENSG00000151655
Gene ExpressionITIH2 [ NCBI-GEO ]   ITIH2 [ EBI - ARRAY_EXPRESS ]   ITIH2 [ SEEK ]   ITIH2 [ MEM ]
Gene Expression Viewer (FireBrowse)ITIH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3698
GTEX Portal (Tissue expression)ITIH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19823   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19823  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19823
Splice isoforms : SwissVarP19823
PhosPhoSitePlusP19823
Domaine pattern : Prosite (Expaxy)VIT (PS51468)    VWFA (PS50234)   
Domains : Interpro (EBI)ITI_HC_C    VIT    VWF_A   
Domain families : Pfam (Sanger)ITI_HC_C (PF06668)    VIT (PF08487)    VWA (PF00092)   
Domain families : Pfam (NCBI)pfam06668    pfam08487    pfam00092   
Domain families : Smart (EMBL)VIT (SM00609)  VWA (SM00327)  
Conserved Domain (NCBI)ITIH2
DMDM Disease mutations3698
Blocks (Seattle)ITIH2
SuperfamilyP19823
Human Protein AtlasENSG00000151655
Peptide AtlasP19823
HPRD00890
IPIIPI00910636   IPI00305461   IPI00645038   IPI00514159   
Protein Interaction databases
DIP (DOE-UCLA)P19823
IntAct (EBI)P19823
FunCoupENSG00000151655
BioGRIDITIH2
STRING (EMBL)ITIH2
ZODIACITIH2
Ontologies - Pathways
QuickGOP19823
Ontology : AmiGOendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  hyaluronan metabolic process  extracellular exosome  blood microparticle  
Ontology : EGO-EBIendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  hyaluronan metabolic process  extracellular exosome  blood microparticle  
NDEx NetworkITIH2
Atlas of Cancer Signalling NetworkITIH2
Wikipedia pathwaysITIH2
Orthology - Evolution
OrthoDB3698
GeneTree (enSembl)ENSG00000151655
Phylogenetic Trees/Animal Genes : TreeFamITIH2
HOVERGENP19823
HOGENOMP19823
Homologs : HomoloGeneITIH2
Homology/Alignments : Family Browser (UCSC)ITIH2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerITIH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ITIH2
dbVarITIH2
ClinVarITIH2
1000_GenomesITIH2 
Exome Variant ServerITIH2
ExAC (Exome Aggregation Consortium)ITIH2 (select the gene name)
Genetic variants : HAPMAP3698
Genomic Variants (DGV)ITIH2 [DGVbeta]
DECIPHERITIH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisITIH2 
Mutations
ICGC Data PortalITIH2 
TCGA Data PortalITIH2 
Broad Tumor PortalITIH2
OASIS PortalITIH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICITIH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDITIH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ITIH2
DgiDB (Drug Gene Interaction Database)ITIH2
DoCM (Curated mutations)ITIH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ITIH2 (select a term)
intoGenITIH2
Cancer3DITIH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146640   
Orphanet
MedgenITIH2
Genetic Testing Registry ITIH2
NextProtP19823 [Medical]
TSGene3698
GENETestsITIH2
Target ValidationITIH2
Huge Navigator ITIH2 [HugePedia]
snp3D : Map Gene to Disease3698
BioCentury BCIQITIH2
ClinGenITIH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3698
Chemical/Pharm GKB GenePA29965
Clinical trialITIH2
Miscellaneous
canSAR (ICR)ITIH2 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineITIH2
EVEXITIH2
GoPubMedITIH2
iHOPITIH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:04:18 CEST 2017

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