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ITIH5 (inter-alpha-trypsin inhibitor heavy chain family member 5)

Identity

Alias_namesinter-alpha (globulin) inhibitor H5
inter-alpha-trypsin inhibitor heavy chain family, member 5
Alias_symbol (synonym)MGC10848
Other aliasITI-HC5
PP14776
HGNC (Hugo) ITIH5
LocusID (NCBI) 80760
Atlas_Id 43692
Location 10p14  [Link to chromosome band 10p14]
Location_base_pair Starts at 7571405 and ends at 7666998 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITIH5 (10p14) / ITIH5 (10p14)ITIH5 (10p14) / PELP1 (17p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ITIH5   21449
Cards
Entrez_Gene (NCBI)ITIH5  80760  inter-alpha-trypsin inhibitor heavy chain family member 5
AliasesITI-HC5; PP14776
GeneCards (Weizmann)ITIH5
Ensembl hg19 (Hinxton)ENSG00000123243 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123243 [Gene_View]  chr10:7571405-7666998 [Contig_View]  ITIH5 [Vega]
ICGC DataPortalENSG00000123243
TCGA cBioPortalITIH5
AceView (NCBI)ITIH5
Genatlas (Paris)ITIH5
WikiGenes80760
SOURCE (Princeton)ITIH5
Genetics Home Reference (NIH)ITIH5
Genomic and cartography
GoldenPath hg38 (UCSC)ITIH5  -     chr10:7571405-7666998 -  10p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ITIH5  -     10p14   [Description]    (hg19-Feb_2009)
EnsemblITIH5 - 10p14 [CytoView hg19]  ITIH5 - 10p14 [CytoView hg38]
Mapping of homologs : NCBIITIH5 [Mapview hg19]  ITIH5 [Mapview hg38]
OMIM609783   
Gene and transcription
Genbank (Entrez)AB075833 AF318347 AK027375 AK027547 AK027831
RefSeq transcript (Entrez)NM_001001851 NM_030569 NM_032817
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ITIH5
Cluster EST : UnigeneHs.732936 [ NCBI ]
CGAP (NCI)Hs.732936
Alternative Splicing GalleryENSG00000123243
Gene ExpressionITIH5 [ NCBI-GEO ]   ITIH5 [ EBI - ARRAY_EXPRESS ]   ITIH5 [ SEEK ]   ITIH5 [ MEM ]
Gene Expression Viewer (FireBrowse)ITIH5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80760
GTEX Portal (Tissue expression)ITIH5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UX2
Splice isoforms : SwissVarQ86UX2
PhosPhoSitePlusQ86UX2
Domaine pattern : Prosite (Expaxy)VIT (PS51468)    VWFA (PS50234)   
Domains : Interpro (EBI)ITI_HC_C    VIT    VWF_A   
Domain families : Pfam (Sanger)ITI_HC_C (PF06668)    VIT (PF08487)    VWA_3 (PF13768)   
Domain families : Pfam (NCBI)pfam06668    pfam08487    pfam13768   
Domain families : Smart (EMBL)VIT (SM00609)  VWA (SM00327)  
Conserved Domain (NCBI)ITIH5
DMDM Disease mutations80760
Blocks (Seattle)ITIH5
SuperfamilyQ86UX2
Human Protein AtlasENSG00000123243
Peptide AtlasQ86UX2
HPRD07865
IPIIPI00292452   IPI00872582   IPI00939912   IPI00428234   IPI00328829   IPI00451977   IPI00945408   
Protein Interaction databases
DIP (DOE-UCLA)Q86UX2
IntAct (EBI)Q86UX2
FunCoupENSG00000123243
BioGRIDITIH5
STRING (EMBL)ITIH5
ZODIACITIH5
Ontologies - Pathways
QuickGOQ86UX2
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  hyaluronan metabolic process  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  hyaluronan metabolic process  
NDEx NetworkITIH5
Atlas of Cancer Signalling NetworkITIH5
Wikipedia pathwaysITIH5
Orthology - Evolution
OrthoDB80760
GeneTree (enSembl)ENSG00000123243
Phylogenetic Trees/Animal Genes : TreeFamITIH5
HOVERGENQ86UX2
HOGENOMQ86UX2
Homologs : HomoloGeneITIH5
Homology/Alignments : Family Browser (UCSC)ITIH5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerITIH5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ITIH5
dbVarITIH5
ClinVarITIH5
1000_GenomesITIH5 
Exome Variant ServerITIH5
ExAC (Exome Aggregation Consortium)ITIH5 (select the gene name)
Genetic variants : HAPMAP80760
Genomic Variants (DGV)ITIH5 [DGVbeta]
DECIPHERITIH5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisITIH5 
Mutations
ICGC Data PortalITIH5 
TCGA Data PortalITIH5 
Broad Tumor PortalITIH5
OASIS PortalITIH5 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDITIH5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ITIH5
DgiDB (Drug Gene Interaction Database)ITIH5
DoCM (Curated mutations)ITIH5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ITIH5 (select a term)
intoGenITIH5
Cancer3DITIH5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609783   
Orphanet
MedgenITIH5
Genetic Testing Registry ITIH5
NextProtQ86UX2 [Medical]
TSGene80760
GENETestsITIH5
Target ValidationITIH5
Huge Navigator ITIH5 [HugePedia]
snp3D : Map Gene to Disease80760
BioCentury BCIQITIH5
ClinGenITIH5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80760
Chemical/Pharm GKB GenePA134899668
Clinical trialITIH5
Miscellaneous
canSAR (ICR)ITIH5 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineITIH5
EVEXITIH5
GoPubMedITIH5
iHOPITIH5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:38:58 CEST 2017

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