Identity
HGNC
LOCATION
10p14
LOCUSID
ALIAS
ITI-HC5,PP14776
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80760
MIM: 609783
HGNC: 21449
Ensembl: ENSG00000123243
Variants:
dbSNP: 80760
ClinVar: 80760
TCGA: ENSG00000123243
COSMIC: ITIH5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000123243 | ENST00000397145 | G5E9D8 |
| ENSG00000123243 | ENST00000397146 | C9J2H1 |
| ENSG00000123243 | ENST00000461751 | H7C5A6 |
| ENSG00000123243 | ENST00000613909 | A0A096LP62 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38375974 | 2024 | ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration. | 0 |
| 38375974 | 2024 | ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration. | 0 |
| 33024269 | 2021 | Suppression of pancreatic cancer liver metastasis by secretion-deficient ITIH5. | 8 |
| 33924987 | 2021 | The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells. | 8 |
| 33935281 | 2021 | ITIH5, a p53-responsive gene, inhibits the growth and metastasis of melanoma cells by downregulating the transcriptional activity of KLF4. | 10 |
| 33024269 | 2021 | Suppression of pancreatic cancer liver metastasis by secretion-deficient ITIH5. | 8 |
| 33924987 | 2021 | The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells. | 8 |
| 33935281 | 2021 | ITIH5, a p53-responsive gene, inhibits the growth and metastasis of melanoma cells by downregulating the transcriptional activity of KLF4. | 10 |
| 31887566 | 2020 | Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. | 17 |
| 32799206 | 2020 | Inter-α-Trypsin Inhibitor Heavy Chain 5 (ITIH5) Is a Natural Stabilizer of Hyaluronan That Modulates Biological Processes in the Skin. | 11 |
| 31887566 | 2020 | Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. | 17 |
| 32799206 | 2020 | Inter-α-Trypsin Inhibitor Heavy Chain 5 (ITIH5) Is a Natural Stabilizer of Hyaluronan That Modulates Biological Processes in the Skin. | 11 |
| 28940371 | 2018 | ITIH5 induces a shift in TGF-β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death. | 15 |
| 29626357 | 2018 | Aberrant expression of LncRNA-MIR31HG regulates cell migration and proliferation by affecting miR-31 and miR-31* in Hirschsprung's disease. | 19 |
| 28940371 | 2018 | ITIH5 induces a shift in TGF-β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death. | 15 |
Citation
Dessen P
ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43692/itih5
