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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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ITM2B (integral membrane protein 2B)

Identity

Other namesABRI
BRI
BRI2
BRICD2B
E25B
E3-16
FBD
imBRI2
HGNC (Hugo) ITM2B
LocusID (NCBI) 9445
Location 13q14.2
Location_base_pair Starts at 48807274 and ends at 48836232 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ITM2B   6174
Cards
Entrez_Gene (NCBI)ITM2B  9445  integral membrane protein 2B
GeneCards (Weizmann)ITM2B
Ensembl hg19 (Hinxton)ENSG00000136156 [Gene_View]  chr13:48807274-48836232 [Contig_View]  ITM2B [Vega]
Ensembl hg38 (Hinxton)ENSG00000136156 [Gene_View]  chr13:48807274-48836232 [Contig_View]  ITM2B [Vega]
ICGC DataPortalENSG00000136156
cBioPortalITM2B
AceView (NCBI)ITM2B
Genatlas (Paris)ITM2B
WikiGenes9445
SOURCE (Princeton)ITM2B
Genomic and cartography
GoldenPath hg19 (UCSC)ITM2B  -     chr13:48807274-48836232 +  13q14.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ITM2B  -     13q14.2   [Description]    (hg38-Dec_2013)
EnsemblITM2B - 13q14.2 [CytoView hg19]  ITM2B - 13q14.2 [CytoView hg38]
Mapping of homologs : NCBIITM2B [Mapview hg19]  ITM2B [Mapview hg38]
OMIM117300   176500   603904   
Gene and transcription
Genbank (Entrez)AF086918 AF092128 AF136973 AF152462 AF246221
RefSeq transcript (Entrez)NM_021999
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NG_013069 NT_024524 NW_001838074 NW_004929388
Consensus coding sequences : CCDS (NCBI)ITM2B
Cluster EST : UnigeneHs.643683 [ NCBI ]
CGAP (NCI)Hs.643683
Alternative Splicing : Fast-db (Paris)GSHG0008104
Alternative Splicing GalleryENSG00000136156
Gene ExpressionITM2B [ NCBI-GEO ]     ITM2B [ SEEK ]   ITM2B [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y287 (Uniprot)
NextProtQ9Y287  [Medical]
With graphics : InterProQ9Y287
Splice isoforms : SwissVarQ9Y287 (Swissvar)
Domaine pattern : Prosite (Expaxy)BRICHOS (PS50869)   
Domains : Interpro (EBI)BRICHOS_dom   
Related proteins : CluSTrQ9Y287
Domain families : Pfam (Sanger)BRICHOS (PF04089)   
Domain families : Pfam (NCBI)pfam04089   
Domain families : Smart (EMBL)BRICHOS (SM01039)  
DMDM Disease mutations9445
Blocks (Seattle)Q9Y287
Human Protein AtlasENSG00000136156
Peptide AtlasQ9Y287
HPRD04878
IPIIPI00031821   IPI00477987   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y287
IntAct (EBI)Q9Y287
FunCoupENSG00000136156
BioGRIDITM2B
IntegromeDBITM2B
STRING (EMBL)ITM2B
Ontologies - Pathways
QuickGOQ9Y287
Ontology : AmiGObeta-amyloid binding  protein binding  ATP binding  extracellular region  extracellular space  Golgi apparatus  plasma membrane  nervous system development  endosome membrane  membrane  Golgi-associated vesicle membrane  integral component of organelle membrane  negative regulation of amyloid precursor protein biosynthetic process  intracellular membrane-bounded organelle  extracellular vesicular exosome  extrinsic apoptotic signaling pathway in absence of ligand  
Ontology : EGO-EBIbeta-amyloid binding  protein binding  ATP binding  extracellular region  extracellular space  Golgi apparatus  plasma membrane  nervous system development  endosome membrane  membrane  Golgi-associated vesicle membrane  integral component of organelle membrane  negative regulation of amyloid precursor protein biosynthetic process  intracellular membrane-bounded organelle  extracellular vesicular exosome  extrinsic apoptotic signaling pathway in absence of ligand  
Protein Interaction DatabaseITM2B
DoCM (Curated mutations)ITM2B
Wikipedia pathwaysITM2B
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerITM2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ITM2B
dbVarITM2B
ClinVarITM2B
1000_GenomesITM2B 
Exome Variant ServerITM2B
SNP (GeneSNP Utah)ITM2B
SNP : HGBaseITM2B
Genetic variants : HAPMAPITM2B
Genomic Variants (DGV)ITM2B [DGVbeta]
Mutations
ICGC Data PortalENSG00000136156 
Somatic Mutations in Cancer : COSMICITM2B 
CONAN: Copy Number AnalysisITM2B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)13:48807274-48836232
Mutations and Diseases : HGMDITM2B
OMIM117300    176500    603904   
MedgenITM2B
NextProtQ9Y287 [Medical]
GENETestsITM2B
Disease Genetic AssociationITM2B
Huge Navigator ITM2B [HugePedia]  ITM2B [HugeCancerGEM]
snp3D : Map Gene to Disease9445
DGIdb (Drug Gene Interaction db)ITM2B
General knowledge
Homologs : HomoloGeneITM2B
Homology/Alignments : Family Browser (UCSC)ITM2B
Phylogenetic Trees/Animal Genes : TreeFamITM2B
Chemical/Protein Interactions : CTD9445
Chemical/Pharm GKB GenePA29971
Clinical trialITM2B
Cancer Resource (Charite)ENSG00000136156
Other databases
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
CoreMineITM2B
GoPubMedITM2B
iHOPITM2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 16:22:48 CET 2015

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