| CIRBP-AS1 (19p13.3) / ITPK1 (14q32.12) | ITPK1 (14q32.12) / ACO1 (9p21.1) | ITPK1 (14q32.12) / ADH5 (4q23) |
|
ITPK1 (14q32.12) / BTBD7 (14q32.12) | ITPK1 (14q32.12) / CEP170B (14q32.33) | ITPK1 (14q32.12) / EHBP1L1 (11q13.1) |
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ITPK1 (14q32.12) / ISM2 (14q24.3) | ITPK1 (14q32.12) / KLHL29 (2p24.1) | SYNE2 (14q23.2) / ITPK1 (14q32.12) |
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ITPK1 ACO1 | ITPK1 BTBD7 | ITPK1 KIAA0284 |
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| Nomenclature |
HGNC (Hugo) | ITPK1 6177 |
| Cards |
Entrez_Gene (NCBI) | ITPK1 inositol-tetrakisphosphate 1-kinase |
Aliases | ITRPK1 |
GeneCards (Weizmann) | ITPK1 |
Ensembl hg19 (Hinxton) | ENSG00000100605 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000100605 [Gene_View]  ENSG00000100605 [Sequence] chr14:92939723-93115919 [Contig_View] ITPK1 [Vega] |
ICGC DataPortal | ENSG00000100605 |
TCGA cBioPortal | ITPK1 |
AceView (NCBI) | ITPK1 |
Genatlas (Paris) | ITPK1 |
SOURCE (Princeton) | ITPK1 |
Genetics Home Reference (NIH) | ITPK1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | ITPK1 - chr14:92939723-93115919 - 14q32.12 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | ITPK1 - 14q32.12 [Description] (hg19-Feb_2009) |
GoldenPath | ITPK1 - 14q32.12 [CytoView hg19] ITPK1 - 14q32.12 [CytoView hg38] |
ImmunoBase | ENSG00000100605 |
genome Data Viewer NCBI | ITPK1 [Mapview hg19] |
OMIM | 601838 |
| Gene and transcription |
Genbank (Entrez) | AA770154 AF279372 AK293515 AY129028 BC003622 |
RefSeq transcript (Entrez) | NM_001142593 NM_001142594 NM_001363707 NM_014216 |
RefSeq genomic (Entrez) | NC_000014 NG_051071 NT_187601 |
Consensus coding sequences : CCDS (NCBI) | ITPK1 |
Alternative Splicing Gallery | ENSG00000100605 |
Gene Expression | ITPK1 [ NCBI-GEO ] ITPK1 [ EBI - ARRAY_EXPRESS ]
ITPK1 [ SEEK ] ITPK1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | ITPK1 [ Firebrowse - Broad ] |
Genevisible | Expression of ITPK1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 3705 |
GTEX Portal (Tissue expression) | ITPK1 |
Human Protein Atlas | ENSG00000100605-ITPK1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q13572 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q13572 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q13572 |
Splice isoforms : SwissVar | Q13572 |
Catalytic activity : Enzyme | 2.7.1.134 [ Enzyme-Expasy ] 2.7.1.1342.7.1.134 [ IntEnz-EBI ] 2.7.1.134 [ BRENDA ] 2.7.1.134 [ KEGG ] [ MEROPS ] |
PhosPhoSitePlus | Q13572 |
Domaine pattern : Prosite (Expaxy) | ATP_GRASP (PS50975) |
Domains : Interpro (EBI) | ATP-grasp Inositol_tetrakis-P_1-kinase InsP(3)kin_ATP-grasp ITPK1_N |
Domain families : Pfam (Sanger) | Ins134_P3_kin (PF05770) Ins134_P3_kin_N (PF17927) |
Domain families : Pfam (NCBI) | pfam05770 pfam17927 |
Conserved Domain (NCBI) | ITPK1 |
Blocks (Seattle) | ITPK1 |
PDB (RSDB) | 2ODT 2Q7D 2QB5 |
PDB Europe | 2ODT 2Q7D 2QB5 |
PDB (PDBSum) | 2ODT 2Q7D 2QB5 |
PDB (IMB) | 2ODT 2Q7D 2QB5 |
Structural Biology KnowledgeBase | 2ODT 2Q7D 2QB5 |
SCOP (Structural Classification of Proteins) | 2ODT 2Q7D 2QB5 |
CATH (Classification of proteins structures) | 2ODT 2Q7D 2QB5 |
Superfamily | Q13572 |
Human Protein Atlas [tissue] | ENSG00000100605-ITPK1 [tissue] |
Peptide Atlas | Q13572 |
HPRD | 03501 |
IPI | IPI00100329 IPI00953716 IPI00165371 IPI00296589 IPI01026041 IPI01025710 IPI01025837 IPI01025489 IPI01025373 IPI00977107 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q13572 |
IntAct (EBI) | Q13572 |
BioGRID | ITPK1 |
STRING (EMBL) | ITPK1 |
ZODIAC | ITPK1 |
| Ontologies - Pathways |
QuickGO | Q13572 |
Ontology : AmiGO | magnesium ion binding inositol tetrakisphosphate 6-kinase activity catalytic activity ATP binding cytoplasm cytosol signal transduction blood coagulation apical plasma membrane hydrolase activity isomerase activity neural tube development inositol trisphosphate metabolic process inositol phosphate metabolic process inositol tetrakisphosphate 1-kinase activity inositol tetrakisphosphate 1-kinase activity inositol-1,3,4-trisphosphate 6-kinase activity inositol-1,3,4-trisphosphate 6-kinase activity inositol-1,3,4-trisphosphate 5-kinase activity inositol-1,3,4-trisphosphate 5-kinase activity inositol phosphorylation necroptotic process |
Ontology : EGO-EBI | magnesium ion binding inositol tetrakisphosphate 6-kinase activity catalytic activity ATP binding cytoplasm cytosol signal transduction blood coagulation apical plasma membrane hydrolase activity isomerase activity neural tube development inositol trisphosphate metabolic process inositol phosphate metabolic process inositol tetrakisphosphate 1-kinase activity inositol tetrakisphosphate 1-kinase activity inositol-1,3,4-trisphosphate 6-kinase activity inositol-1,3,4-trisphosphate 6-kinase activity inositol-1,3,4-trisphosphate 5-kinase activity inositol-1,3,4-trisphosphate 5-kinase activity inositol phosphorylation necroptotic process |
NDEx Network | ITPK1 |
Atlas of Cancer Signalling Network | ITPK1 |
Wikipedia pathways | ITPK1 |
| Orthology - Evolution |
OrthoDB | 3705 |
GeneTree (enSembl) | ENSG00000100605 |
Phylogenetic Trees/Animal Genes : TreeFam | ITPK1 |
HOGENOM | Q13572 |
Homologs : HomoloGene | ITPK1 |
Homology/Alignments : Family Browser (UCSC) | ITPK1 |
| Gene fusions - Rearrangements |
Fusion Portal | ITPK1 ACO1 |
Fusion Portal | ITPK1 BTBD7 |
Fusion Portal | ITPK1 KIAA0284 |
Fusion : Quiver | ITPK1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | ITPK1 [hg38] |
dbVar | ITPK1 |
ClinVar | ITPK1 |
Monarch | ITPK1 |
1000_Genomes | ITPK1 |
Exome Variant Server | ITPK1 |
GNOMAD Browser | ENSG00000100605 |
Varsome Browser | ITPK1 |
Genomic Variants (DGV) | ITPK1 [DGVbeta] |
DECIPHER | ITPK1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | ITPK1 |
| Mutations |
ICGC Data Portal | ITPK1 |
TCGA Data Portal | ITPK1 |
Broad Tumor Portal | ITPK1 |
OASIS Portal | ITPK1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | ITPK1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | ITPK1 |
Mutations and Diseases : HGMD | ITPK1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search ITPK1 |
DgiDB (Drug Gene Interaction Database) | ITPK1 |
DoCM (Curated mutations) | ITPK1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | ITPK1 (select a term) |
intoGen | ITPK1 |
Cancer3D | ITPK1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 601838 |
Orphanet | |
DisGeNET | ITPK1 |
Medgen | ITPK1 |
Genetic Testing Registry | ITPK1
|
NextProt | Q13572 [Medical] |
GENETests | ITPK1 |
Target Validation | ITPK1 |
Huge Navigator |
ITPK1 [HugePedia] |
ClinGen | ITPK1 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | ITPK1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA29974 |
Clinical trial | ITPK1 |
| Miscellaneous |
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canSAR (ICR) | ITPK1 (select the gene name) |
Harmonizome | ITPK1 |
DataMed Index | ITPK1 |
| Probes |
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| Litterature |
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PubMed | 32 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | ITPK1 |
EVEX | ITPK1 |
GoPubMed | ITPK1 |