| Nomenclature | | HGNC (Hugo) | ITPR2 6181 |
| Entrez_Gene (NCBI) | ITPR2 3709 inositol 1,4,5-trisphosphate receptor, type 2 |
| Cards | | GeneCards (Weizmann) | ITPR2 |
| Ensembl (Hinxton) | ENSG00000123104 [Gene_View] chr12:26488285-26986131 [Contig_View] ITPR2 [Vega] |
| AceView (NCBI) | ITPR2 |
| Genatlas (Paris) | ITPR2 |
| SOURCE (Stanford) | NM_002223 |
| Genomic and cartography | | GoldenPath (UCSC) | ITPR2 - 12p12.1 chr12:26488285-26986131 - 12p12.1 [Description] (hg19-Feb_2009) |
| Ensembl | ITPR2 - 12p12.1 [CytoView] |
| Mapping of homologs : NCBI | ITPR2 [Mapview] |
| OMIM | 600144 |
| Gene and transcription |
| Genbank (Entrez) | AB012610 AK307686 AK307712 AK310504 AL711179 |
| RefSeq transcript (SRS) | NM_002223 |
| RefSeq transcript (Entrez) | NM_002223 |
| RefSeq genomic (SRS) | AC_000144 NC_000012 NC_018923 NT_009714 NW_001838052 NW_004078074 |
| RefSeq genomic (Entrez) | AC_000144 NC_000012 NC_018923 NT_009714 NW_001838052 NW_004078074 |
| Consensus coding sequences : CCDS (NCBI) | ITPR2 |
| Cluster EST : Unigene | Hs.512235 [ SRS ] Hs.512235 [ NCBI ] |
| CGAP (NCI) | Hs.512235 |
| Alternative Splicing : Fast-db (Paris) | GSHG0007339 |
| Alternative Splicing Gallery | ENSG00000123104 |
| Gene Expression | ITPR2 [ NCBI-GEO ] ITPR2 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q14571 (SRS) Q14571 (Uniprot) |
| NextProt | Q14571 |
| With graphics : InterPro | Q14571 |
| Splice isoforms : SwissVar | Q14571(Swissvar) |
| Domaine pattern : Prosite (SRS) | MIR (PS50919) |
| Domaine pattern : Prosite (Expaxy) | MIR (PS50919) |
| Domains : Interpro (SRS) | Ca-rel_channel Ins145_P3_rcpt InsP3_rcpt-bd Ion_trans_dom MIR_motif RIH_assoc-dom Ryanodine_recept-rel |
| Domains : Interpro (EBI) | Ca-rel_channel Ins145_P3_rcpt InsP3_rcpt-bd Ion_trans_dom MIR_motif RIH_assoc-dom Ryanodine_recept-rel |
| Related proteins : CluSTr | Q14571 |
| Domain families : Pfam (SRS) | Ins145_P3_rec (PF08709) Ion_trans (PF00520) MIR (PF02815) RIH_assoc (PF08454) RYDR_ITPR (PF01365) |
| Domain families : Pfam (Sanger) | Ins145_P3_rec (PF08709) Ion_trans (PF00520) MIR (PF02815) RIH_assoc (PF08454) RYDR_ITPR (PF01365) |
| Domain families : Pfam (NCBI) | pfam08709 pfam00520 pfam02815 pfam08454 pfam01365 |
| Domain families : Smart (EMBL) | MIR (SM00472) |
| DMDM | 3709 |
| Blocks (Seattle) | Q14571 |
| Human Protein Atlas | ENSG00000123104 |
| HPRD | 02536 |
| IPI | IPI00031545 IPI00218668 IPI00790132 IPI01014569 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q14571 |
| IntAct (EBI) | Q14571 |
| FunCoup | ENSG00000123104 |
| REACTOME | ITPR2 |
| Protein Interaction Database | 3709 |
| BioGRID | ITPR2 |
| InParanoid | Q14571 |
| Interologous Interaction database | Q14571 |
| IntegromeDB | ITPR2 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | ITPR2 |
| SNP (GeneSNP Utah) | ITPR2 |
| SNP : HGBase | ITPR2 |
| Genetic variants : HAPMAP | ITPR2 |
| Somatic Mutations in Cancer : COSMIC | ITPR2 |
| CONAN: Copy Number Analysis | ITPR2 |
| Translocation Breakpoints in Cancer : TICdb | ITPR2 |
| Mutations and Diseases : HGMD | ITPR2 |
| OMIM | 600144 |
| GENETests | 600144 |
| Disease Genetic Association | ITPR2 |
| Huge Navigator |
ITPR2 [HugePedia] ITPR2 [HugeCancerGEM] |
| Genomic Variants | ITPR2 ITPR2 [DGVbeta] |
| snp3D : Map Gene to Disease | 3709 |
| General knowledge |
|---|
| Homologs : HomoloGene | ITPR2 |
| Homology/Alignments : Family Browser (UCSC) | ITPR2 |
| Phylogenetic Trees/Animal Genes : TreeFam | ITPR2 |
| Chemical/Protein Interactions : CTD | 3709 |
| Chemical/Pharm GKB Gene | PA29979 |
| Clinical trial | ITPR2 |
| Cancer Resource (Charite) | ENSG00000123104 |
| Ontology : AmiGO | response to hypoxia inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity endoplasmic reticulum membrane plasma membrane cell cortex energy reserve metabolic process transport signal transduction epidermal growth factor receptor signaling pathway activation of phospholipase C activity blood coagulation fibroblast growth factor receptor signaling pathway calcium ion transmembrane transporter activity integral to membrane platelet activation platelet dense tubular network membrane sarcoplasmic reticulum membrane phosphatidylinositol binding small molecule metabolic process nerve growth factor receptor signaling pathway regulation of insulin secretion cellular response to cAMP |
| Ontology : EGO-EBI | response to hypoxia inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity endoplasmic reticulum membrane plasma membrane cell cortex energy reserve metabolic process transport signal transduction epidermal growth factor receptor signaling pathway activation of phospholipase C activity blood coagulation fibroblast growth factor receptor signaling pathway calcium ion transmembrane transporter activity integral to membrane platelet activation platelet dense tubular network membrane sarcoplasmic reticulum membrane phosphatidylinositol binding small molecule metabolic process nerve growth factor receptor signaling pathway regulation of insulin secretion cellular response to cAMP |
| Pathways : KEGG | Long-term depressionCalcium signaling pathwayGnRH signaling pathwayLong-term potentiationGap junctionPhosphatidylinositol signaling system |
| Other databases | | Probes |
|---|
| Litterature | | PubMed | 39 Pubmed reference(s) in Entrez |
| PubGene | ITPR2 |
| iHOP | ITPR2 |
