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IWS1 (IWS1, SUPT6H interacting protein)

Identity

Alias_namesIWS1 homolog (S. cerevisiae)
Alias_symbol (synonym)DKFZp761G0123
FLJ10006
FLJ14655
FLJ32319
Other alias-
HGNC (Hugo) IWS1
LocusID (NCBI) 55677
Atlas_Id 53884
Location 2q14.3  [Link to chromosome band 2q14]
Location_base_pair Starts at 127480807 and ends at 127526511 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DPYSL2 (8p21.2) / IWS1 (2q14.3)IWS1 (2q14.3) / IWS1 (2q14.3)IWS1 (2q14.3) / SREK1 (5q12.3)
MAP3K2 (2q14.3) / IWS1 (2q14.3)MAP3K2 2q14.3 / IWS1 2q14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IWS1   25467
Cards
Entrez_Gene (NCBI)IWS1  55677  IWS1, SUPT6H interacting protein
Aliases
GeneCards (Weizmann)IWS1
Ensembl hg19 (Hinxton)ENSG00000163166 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163166 [Gene_View]  chr2:127480807-127526511 [Contig_View]  IWS1 [Vega]
ICGC DataPortalENSG00000163166
TCGA cBioPortalIWS1
AceView (NCBI)IWS1
Genatlas (Paris)IWS1
WikiGenes55677
SOURCE (Princeton)IWS1
Genetics Home Reference (NIH)IWS1
Genomic and cartography
GoldenPath hg38 (UCSC)IWS1  -     chr2:127480807-127526511 -  2q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IWS1  -     2q14.3   [Description]    (hg19-Feb_2009)
EnsemblIWS1 - 2q14.3 [CytoView hg19]  IWS1 - 2q14.3 [CytoView hg38]
Mapping of homologs : NCBIIWS1 [Mapview hg19]  IWS1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI638093 AK000868 AK001717 AK027561 AK056881
RefSeq transcript (Entrez)NM_017969
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IWS1
Cluster EST : UnigeneHs.679491 [ NCBI ]
CGAP (NCI)Hs.679491
Alternative Splicing GalleryENSG00000163166
Gene ExpressionIWS1 [ NCBI-GEO ]   IWS1 [ EBI - ARRAY_EXPRESS ]   IWS1 [ SEEK ]   IWS1 [ MEM ]
Gene Expression Viewer (FireBrowse)IWS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55677
GTEX Portal (Tissue expression)IWS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96ST2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96ST2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96ST2
Splice isoforms : SwissVarQ96ST2
PhosPhoSitePlusQ96ST2
Domaine pattern : Prosite (Expaxy)TFIIS_N (PS51319)   
Domains : Interpro (EBI)TFIIS_N   
Domain families : Pfam (Sanger)Med26 (PF08711)   
Domain families : Pfam (NCBI)pfam08711   
Conserved Domain (NCBI)IWS1
DMDM Disease mutations55677
Blocks (Seattle)IWS1
SuperfamilyQ96ST2
Human Protein AtlasENSG00000163166
Peptide AtlasQ96ST2
HPRD07639
IPIIPI00296432   IPI00386012   IPI00908727   IPI00658007   IPI00909451   IPI00448939   IPI00916917   IPI00926021   
Protein Interaction databases
DIP (DOE-UCLA)Q96ST2
IntAct (EBI)Q96ST2
FunCoupENSG00000163166
BioGRIDIWS1
STRING (EMBL)IWS1
ZODIACIWS1
Ontologies - Pathways
QuickGOQ96ST2
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  mRNA processing  RNA splicing  regulation of mRNA export from nucleus  regulation of DNA-templated transcription, elongation  regulation of mRNA processing  mRNA transport  regulation of histone H4 acetylation  regulation of histone H3-K36 trimethylation  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  mRNA processing  RNA splicing  regulation of mRNA export from nucleus  regulation of DNA-templated transcription, elongation  regulation of mRNA processing  mRNA transport  regulation of histone H4 acetylation  regulation of histone H3-K36 trimethylation  
NDEx NetworkIWS1
Atlas of Cancer Signalling NetworkIWS1
Wikipedia pathwaysIWS1
Orthology - Evolution
OrthoDB55677
GeneTree (enSembl)ENSG00000163166
Phylogenetic Trees/Animal Genes : TreeFamIWS1
HOVERGENQ96ST2
HOGENOMQ96ST2
Homologs : HomoloGeneIWS1
Homology/Alignments : Family Browser (UCSC)IWS1
Gene fusions - Rearrangements
Fusion : MitelmanMAP3K2/IWS1 [2q14.3/2q14.3]  [t(2;2)(q14;q14)]  
Fusion: TCGAMAP3K2 2q14.3 IWS1 2q14.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIWS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IWS1
dbVarIWS1
ClinVarIWS1
1000_GenomesIWS1 
Exome Variant ServerIWS1
ExAC (Exome Aggregation Consortium)IWS1 (select the gene name)
Genetic variants : HAPMAP55677
Genomic Variants (DGV)IWS1 [DGVbeta]
DECIPHERIWS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIWS1 
Mutations
ICGC Data PortalIWS1 
TCGA Data PortalIWS1 
Broad Tumor PortalIWS1
OASIS PortalIWS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIWS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIWS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IWS1
DgiDB (Drug Gene Interaction Database)IWS1
DoCM (Curated mutations)IWS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IWS1 (select a term)
intoGenIWS1
Cancer3DIWS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenIWS1
Genetic Testing Registry IWS1
NextProtQ96ST2 [Medical]
TSGene55677
GENETestsIWS1
Target ValidationIWS1
Huge Navigator IWS1 [HugePedia]
snp3D : Map Gene to Disease55677
BioCentury BCIQIWS1
ClinGenIWS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55677
Chemical/Pharm GKB GenePA144596419
Clinical trialIWS1
Miscellaneous
canSAR (ICR)IWS1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIWS1
EVEXIWS1
GoPubMedIWS1
iHOPIWS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:39:02 CEST 2017

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