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JAM2 (junctional adhesion molecule 2)

Identity

Alias_namesC21orf43
Alias_symbol (synonym)VE-JAM
JAM-B
JAMB
CD322
Other aliasPRO245
VEJAM
HGNC (Hugo) JAM2
LocusID (NCBI) 58494
Atlas_Id 53483
Location 21q21.3  [Link to chromosome band 21q21]
Location_base_pair Starts at 25639282 and ends at 25717562 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL1A2 (7q21.3) / JAM2 (21q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)JAM2   14686
Cards
Entrez_Gene (NCBI)JAM2  58494  junctional adhesion molecule 2
AliasesC21orf43; CD322; JAM-B; JAMB; 
PRO245; VE-JAM; VEJAM
GeneCards (Weizmann)JAM2
Ensembl hg19 (Hinxton)ENSG00000154721 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154721 [Gene_View]  chr21:25639282-25717562 [Contig_View]  JAM2 [Vega]
ICGC DataPortalENSG00000154721
TCGA cBioPortalJAM2
AceView (NCBI)JAM2
Genatlas (Paris)JAM2
WikiGenes58494
SOURCE (Princeton)JAM2
Genetics Home Reference (NIH)JAM2
Genomic and cartography
GoldenPath hg38 (UCSC)JAM2  -     chr21:25639282-25717562 +  21q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)JAM2  -     21q21.3   [Description]    (hg19-Feb_2009)
EnsemblJAM2 - 21q21.3 [CytoView hg19]  JAM2 - 21q21.3 [CytoView hg38]
Mapping of homologs : NCBIJAM2 [Mapview hg19]  JAM2 [Mapview hg38]
OMIM606870   
Gene and transcription
Genbank (Entrez)AF255910 AI742752 AK056079 AK294769 AK312708
RefSeq transcript (Entrez)NM_001270407 NM_001270408 NM_021219
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)JAM2
Cluster EST : UnigeneHs.517227 [ NCBI ]
CGAP (NCI)Hs.517227
Alternative Splicing GalleryENSG00000154721
Gene ExpressionJAM2 [ NCBI-GEO ]   JAM2 [ EBI - ARRAY_EXPRESS ]   JAM2 [ SEEK ]   JAM2 [ MEM ]
Gene Expression Viewer (FireBrowse)JAM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58494
GTEX Portal (Tissue expression)JAM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57087   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57087  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57087
Splice isoforms : SwissVarP57087
PhosPhoSitePlusP57087
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)JAM2
DMDM Disease mutations58494
Blocks (Seattle)JAM2
SuperfamilyP57087
Human Protein AtlasENSG00000154721
Peptide AtlasP57087
HPRD06041
IPIIPI00299083   IPI00790678   IPI00909219   IPI00789441   IPI00790020   IPI00979051   IPI00978356   
Protein Interaction databases
DIP (DOE-UCLA)P57087
IntAct (EBI)P57087
FunCoupENSG00000154721
BioGRIDJAM2
STRING (EMBL)JAM2
ZODIACJAM2
Ontologies - Pathways
QuickGOP57087
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  bicellular tight junction  negative regulation of cell adhesion  single organismal cell-cell adhesion  extracellular matrix organization  protein heterodimerization activity  leukocyte migration  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  bicellular tight junction  negative regulation of cell adhesion  single organismal cell-cell adhesion  extracellular matrix organization  protein heterodimerization activity  leukocyte migration  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Epithelial cell signaling in Helicobacter pylori infection   
NDEx NetworkJAM2
Atlas of Cancer Signalling NetworkJAM2
Wikipedia pathwaysJAM2
Orthology - Evolution
OrthoDB58494
GeneTree (enSembl)ENSG00000154721
Phylogenetic Trees/Animal Genes : TreeFamJAM2
HOVERGENP57087
HOGENOMP57087
Homologs : HomoloGeneJAM2
Homology/Alignments : Family Browser (UCSC)JAM2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerJAM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)JAM2
dbVarJAM2
ClinVarJAM2
1000_GenomesJAM2 
Exome Variant ServerJAM2
ExAC (Exome Aggregation Consortium)JAM2 (select the gene name)
Genetic variants : HAPMAP58494
Genomic Variants (DGV)JAM2 [DGVbeta]
DECIPHERJAM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisJAM2 
Mutations
ICGC Data PortalJAM2 
TCGA Data PortalJAM2 
Broad Tumor PortalJAM2
OASIS PortalJAM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICJAM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDJAM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch JAM2
DgiDB (Drug Gene Interaction Database)JAM2
DoCM (Curated mutations)JAM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)JAM2 (select a term)
intoGenJAM2
Cancer3DJAM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606870   
Orphanet
MedgenJAM2
Genetic Testing Registry JAM2
NextProtP57087 [Medical]
TSGene58494
GENETestsJAM2
Huge Navigator JAM2 [HugePedia]
snp3D : Map Gene to Disease58494
BioCentury BCIQJAM2
ClinGenJAM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58494
Chemical/Pharm GKB GenePA29992
Clinical trialJAM2
Miscellaneous
canSAR (ICR)JAM2 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineJAM2
EVEXJAM2
GoPubMedJAM2
iHOPJAM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:21:01 CEST 2017

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