Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

JAM3 (junctional adhesion molecule 3)

Identity

Alias_symbol (synonym)JAM-C
JAMC
Other aliasJAM-2
JAM-3
HGNC (Hugo) JAM3
LocusID (NCBI) 83700
Atlas_Id 45647
Location 11q25  [Link to chromosome band 11q25]
Location_base_pair Starts at 134068925 and ends at 134151757 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
JAM3 (11q25) / EPS8L2 (11p15.5)JAM3 (11q25) / JAM3 (11q25)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)JAM3   15532
Cards
Entrez_Gene (NCBI)JAM3  83700  junctional adhesion molecule 3
AliasesJAM-2; JAM-3; JAM-C; JAMC
GeneCards (Weizmann)JAM3
Ensembl hg19 (Hinxton)ENSG00000166086 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166086 [Gene_View]  chr11:134068925-134151757 [Contig_View]  JAM3 [Vega]
ICGC DataPortalENSG00000166086
TCGA cBioPortalJAM3
AceView (NCBI)JAM3
Genatlas (Paris)JAM3
WikiGenes83700
SOURCE (Princeton)JAM3
Genetics Home Reference (NIH)JAM3
Genomic and cartography
GoldenPath hg38 (UCSC)JAM3  -     chr11:134068925-134151757 +  11q25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)JAM3  -     11q25   [Description]    (hg19-Feb_2009)
EnsemblJAM3 - 11q25 [CytoView hg19]  JAM3 - 11q25 [CytoView hg38]
Mapping of homologs : NCBIJAM3 [Mapview hg19]  JAM3 [Mapview hg38]
OMIM606871   613730   
Gene and transcription
Genbank (Entrez)AF356518 AF448478 AJ344431 AJ416101 AK027435
RefSeq transcript (Entrez)NM_001205329 NM_032801
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)JAM3
Cluster EST : UnigeneHs.150718 [ NCBI ]
CGAP (NCI)Hs.150718
Alternative Splicing GalleryENSG00000166086
Gene ExpressionJAM3 [ NCBI-GEO ]   JAM3 [ EBI - ARRAY_EXPRESS ]   JAM3 [ SEEK ]   JAM3 [ MEM ]
Gene Expression Viewer (FireBrowse)JAM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83700
GTEX Portal (Tissue expression)JAM3
Human Protein AtlasENSG00000166086-JAM3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BX67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BX67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BX67
Splice isoforms : SwissVarQ9BX67
PhosPhoSitePlusQ9BX67
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  IGv (SM00406)  
Conserved Domain (NCBI)JAM3
DMDM Disease mutations83700
Blocks (Seattle)JAM3
SuperfamilyQ9BX67
Human Protein Atlas [tissue]ENSG00000166086-JAM3 [tissue]
Peptide AtlasQ9BX67
HPRD06042
IPIIPI00902570   IPI00152850   IPI00985372   IPI00983157   IPI00985112   IPI00983247   
Protein Interaction databases
DIP (DOE-UCLA)Q9BX67
IntAct (EBI)Q9BX67
FunCoupENSG00000166086
BioGRIDJAM3
STRING (EMBL)JAM3
ZODIACJAM3
Ontologies - Pathways
QuickGOQ9BX67
Ontology : AmiGOangiogenesis  neutrophil homeostasis  adaptive immune response  myeloid progenitor cell differentiation  leukocyte migration involved in inflammatory response  integrin binding  protein binding  extracellular space  plasma membrane  bicellular tight junction  cell-matrix adhesion  spermatid development  integral component of membrane  transmission of nerve impulse  establishment of cell polarity  desmosome  extracellular matrix organization  axon regeneration  paranodal junction  myelination  protein homodimerization activity  Schmidt-Lanterman incisure  cell-cell contact zone  protein heterodimerization activity  leukocyte migration  regulation of neutrophil chemotaxis  regulation of actin cytoskeleton organization by cell-cell adhesion  
Ontology : EGO-EBIangiogenesis  neutrophil homeostasis  adaptive immune response  myeloid progenitor cell differentiation  leukocyte migration involved in inflammatory response  integrin binding  protein binding  extracellular space  plasma membrane  bicellular tight junction  cell-matrix adhesion  spermatid development  integral component of membrane  transmission of nerve impulse  establishment of cell polarity  desmosome  extracellular matrix organization  axon regeneration  paranodal junction  myelination  protein homodimerization activity  Schmidt-Lanterman incisure  cell-cell contact zone  protein heterodimerization activity  leukocyte migration  regulation of neutrophil chemotaxis  regulation of actin cytoskeleton organization by cell-cell adhesion  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Epithelial cell signaling in Helicobacter pylori infection   
NDEx NetworkJAM3
Atlas of Cancer Signalling NetworkJAM3
Wikipedia pathwaysJAM3
Orthology - Evolution
OrthoDB83700
GeneTree (enSembl)ENSG00000166086
Phylogenetic Trees/Animal Genes : TreeFamJAM3
HOVERGENQ9BX67
HOGENOMQ9BX67
Homologs : HomoloGeneJAM3
Homology/Alignments : Family Browser (UCSC)JAM3
Gene fusions - Rearrangements
Tumor Fusion PortalJAM3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerJAM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)JAM3
dbVarJAM3
ClinVarJAM3
1000_GenomesJAM3 
Exome Variant ServerJAM3
ExAC (Exome Aggregation Consortium)ENSG00000166086
GNOMAD BrowserENSG00000166086
Genetic variants : HAPMAP83700
Genomic Variants (DGV)JAM3 [DGVbeta]
DECIPHERJAM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisJAM3 
Mutations
ICGC Data PortalJAM3 
TCGA Data PortalJAM3 
Broad Tumor PortalJAM3
OASIS PortalJAM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICJAM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDJAM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch JAM3
DgiDB (Drug Gene Interaction Database)JAM3
DoCM (Curated mutations)JAM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)JAM3 (select a term)
intoGenJAM3
Cancer3DJAM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606871    613730   
Orphanet21229   
DisGeNETJAM3
MedgenJAM3
Genetic Testing Registry JAM3
NextProtQ9BX67 [Medical]
TSGene83700
GENETestsJAM3
Target ValidationJAM3
Huge Navigator JAM3 [HugePedia]
snp3D : Map Gene to Disease83700
BioCentury BCIQJAM3
ClinGenJAM3 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83700
Chemical/Pharm GKB GenePA29993
Clinical trialJAM3
Miscellaneous
canSAR (ICR)JAM3 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineJAM3
EVEXJAM3
GoPubMedJAM3
iHOPJAM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:18:22 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.